References analysis of the Wikipedia article "리간드 (생화학)" in the Korean version

archives-ouvertes.fr

hal.archives-ouvertes.fr

Soulier JL, Russo O, Giner M, Rivail L, Berthouze M, Ongeri S, Maigret B, Fischmeister R, Lezoualc'h F, Sicsic S, Berque-Bestel I (October 2005). “Design and synthesis of specific probes for human 5-HT4 receptor dimerization studies” (PDF). 《Journal of Medicinal Chemistry》 48 (20): 6220–6228. doi:10.1021/jm050234z. PMID 16190749.

doi.org

dx.doi.org

Teif VB (October 2005). “Ligand-induced DNA condensation: choosing the model”. 《Biophysical Journal》 89 (4): 2574–2587. Bibcode:2005BpJ....89.2574T. doi:10.1529/biophysj.105.063909. PMC 1366757. PMID 16085765.

Teif VB, Rippe K (October 2010). “Statistical-mechanical lattice models for protein-DNA binding in chromatin”. 《Journal of Physics: Condensed Matter》 22 (41): 414105. arXiv:1004.5514. Bibcode:2010JPCM...22O4105T. doi:10.1088/0953-8984/22/41/414105. PMID 21386588. S2CID 103345.

Baron R, Setny P, McCammon JA (September 2010). “Water in cavity-ligand recognition”. 《Journal of the American Chemical Society》 132 (34): 12091–12097. doi:10.1021/ja1050082. PMC 2933114. PMID 20695475.

Baaske P, Wienken CJ, Reineck P, Duhr S, Braun D (March 2010). “Optical thermophoresis for quantifying the buffer dependence of aptamer binding”. 《Angewandte Chemie》 49 (12): 2238–2241. doi:10.1002/anie.200903998. PMID 20186894.

“A hot road to new drugs”. 《Phys.org》. 2010년 2월 24일.
Wienken CJ, Baaske P, Rothbauer U, Braun D, Duhr S (October 2010). “Protein-binding assays in biological liquids using microscale thermophoresis”. 《Nature Communications》 1 (7): 100. Bibcode:2010NatCo...1..100W. doi:10.1038/ncomms1093. PMID 20981028.
Cabanos, C; Wang, M; Han, X; Hansen, SB (2017년 8월 8일). “A Soluble Fluorescent Binding Assay Reveals PIP₂ Antagonism of TREK-1 Channels.”. 《Cell Reports》 20 (6): 1287–1294. doi:10.1016/j.celrep.2017.07.034. PMC 5586213. PMID 28793254.
Matera, Carlo; Pucci, Luca; Fiorentini, Chiara; Fucile, Sergio; Missale, Cristina; Grazioso, Giovanni; Clementi, Francesco; Zoli, Michele; De Amici, Marco (2015년 8월 28일). “Bifunctional compounds targeting both D2 and non-α7 nACh receptors: Design, synthesis and pharmacological characterization”. 《European Journal of Medicinal Chemistry》 101: 367–383. doi:10.1016/j.ejmech.2015.06.039. PMID 26164842.
Matera, Carlo; Flammini, Lisa; Quadri, Marta; Vivo, Valentina; Ballabeni, Vigilio; Holzgrabe, Ulrike; Mohr, Klaus; De Amici, Marco; Barocelli, Elisabetta (2014년 3월 21일). “Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: Synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity”. 《European Journal of Medicinal Chemistry》 75: 222–232. doi:10.1016/j.ejmech.2014.01.032. PMID 24534538.
Erez M, Takemori AE, Portoghese PS (July 1982). “Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites”. 《Journal of Medicinal Chemistry》 25 (7): 847–849. doi:10.1021/jm00349a016. PMID 7108900.
Portoghese PS, Ronsisvalle G, Larson DL, Yim CB, Sayre LM, Takemori AE (1982). “Opioid agonist and antagonist bivalent ligands as receptor probes”. 《Life Sciences》 31 (12–13): 1283–1286. doi:10.1016/0024-3205(82)90362-9. PMID 6292615.
Portoghese PS, Akgün E, Lunzer MM (January 2017). “Heteromer Induction: An Approach to Unique Pharmacology?”. 《ACS Chemical Neuroscience》 8 (3): 426–428. doi:10.1021/acschemneuro.7b00002. PMID 28139906.
Blum JJ, Conn PM (December 1982). “Gonadotropin-releasing hormone stimulation of luteinizing hormone release: A ligand-receptor-effector model”. 《Proceedings of the National Academy of Sciences of the United States of America》 79 (23): 7307–7311. Bibcode:1982PNAS...79.7307B. doi:10.1073/pnas.79.23.7307. JSTOR 13076. PMC 347328. PMID 6296828.
Conn PM, Rogers DC, Stewart JM, Niedel J, Sheffield T (April 1982). “Conversion of a gonadotropin-releasing hormone antagonist to an agonist”. 《Nature》 296 (5858): 653–655. Bibcode:1982Natur.296..653C. doi:10.1038/296653a0. PMID 6280058. S2CID 4303982.
Nimczick M, Pemp D, Darras FH, Chen X, Heilmann J, Decker M (August 2014). “Synthesis and biological evaluation of bivalent cannabinoid receptor ligands based on hCB₂R selective benzimidazoles reveal unexpected intrinsic properties”. 《Bioorganic & Medicinal Chemistry》 22 (15): 3938–3946. doi:10.1016/j.bmc.2014.06.008. PMID 24984935.
Russo O, Berthouze M, Giner M, Soulier JL, Rivail L, Sicsic S, Lezoualc'h F, Jockers R, Berque-Bestel I (September 2007). “Synthesis of specific bivalent probes that functionally interact with 5-HT(4) receptor dimers”. 《Journal of Medicinal Chemistry》 50 (18): 4482–4492. doi:10.1021/jm070552t. PMID 17676726.
Soulier JL, Russo O, Giner M, Rivail L, Berthouze M, Ongeri S, Maigret B, Fischmeister R, Lezoualc'h F, Sicsic S, Berque-Bestel I (October 2005). “Design and synthesis of specific probes for human 5-HT4 receptor dimerization studies” (PDF). 《Journal of Medicinal Chemistry》 48 (20): 6220–6228. doi:10.1021/jm050234z. PMID 16190749.
Busnelli M, Kleinau G, Muttenthaler M, Stoev S, Manning M, Bibic L, Howell LA, McCormick PJ, Di Lascio S, Braida D, Sala M, Rovati GE, Bellini T, Chini B (August 2016). “Design and Characterization of Superpotent Bivalent Ligands Targeting Oxytocin Receptor Dimers via a Channel-Like Structure”. 《Journal of Medicinal Chemistry》 59 (15): 7152–7166. doi:10.1021/acs.jmedchem.6b00564. hdl:2434/430357. PMID 27420737.
Lensing CJ, Adank DN, Wilber SL, Freeman KT, Schnell SM, Speth RC, Zarth AT, Haskell-Luevano C (February 2017). “A Direct in Vivo Comparison of the Melanocortin Monovalent Agonist Ac-His-DPhe-Arg-Trp-NH2 versus the Bivalent Agonist Ac-His-DPhe-Arg-Trp-PEDG20-His-DPhe-Arg-Trp-NH2: A Bivalent Advantage”. 《ACS Chemical Neuroscience》 8 (6): 1262–1278. doi:10.1021/acschemneuro.6b00399. PMC 5679024. PMID 28128928.
Xu L, Josan JS, Vagner J, Caplan MR, Hruby VJ, Mash EA, Lynch RM, Morse DL, Gillies RJ (December 2012). “Heterobivalent ligands target cell-surface receptor combinations in vivo”. 《Proceedings of the National Academy of Sciences of the United States of America》 109 (52): 21295–21300. Bibcode:2012PNAS..10921295X. doi:10.1073/pnas.1211762109. JSTOR 42553664. PMC 3535626. PMID 23236171.
Lensing CJ, Freeman KT, Schnell SM, Adank DN, Speth RC, Haskell-Luevano C (April 2016). “An in Vitro and in Vivo Investigation of Bivalent Ligands That Display Preferential Binding and Functional Activity for Different Melanocortin Receptor Homodimers”. 《Journal of Medicinal Chemistry》 59 (7): 3112–3128. doi:10.1021/acs.jmedchem.5b01894. PMC 5679017. PMID 26959173.
Shonberg J, Scammells PJ, Capuano B (June 2011). “Design strategies for bivalent ligands targeting GPCRs”. 《ChemMedChem》 6 (6): 963–974. doi:10.1002/cmdc.201100101. PMID 21520422. S2CID 10561038.
Berque-Bestel I, Lezoualc'h F, Jockers R (December 2008). “Bivalent ligands as specific pharmacological tools for G protein-coupled receptor dimers”. 《Current Drug Discovery Technologies》 5 (4): 312–318. doi:10.2174/157016308786733591. PMID 19075611.
Akgün E, Javed MI, Lunzer MM, Powers MD, Sham YY, Watanabe Y, Portoghese PS (November 2015). “Inhibition of Inflammatory and Neuropathic Pain by Targeting a Mu Opioid Receptor/Chemokine Receptor5 Heteromer (MOR-CCR5)”. 《Journal of Medicinal Chemistry》 58 (21): 8647–8657. doi:10.1021/acs.jmedchem.5b01245. PMC 5055304. PMID 26451468.
Daniels DJ, Lenard NR, Etienne CL, Law PY, Roerig SC, Portoghese PS (December 2005). “Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series”. 《Proceedings of the National Academy of Sciences of the United States of America》 102 (52): 19208–19213. Bibcode:2005PNAS..10219208D. doi:10.1073/pnas.0506627102. JSTOR 4152590. PMC 1323165. PMID 16365317.
Smeester BA, Lunzer MM, Akgün E, Beitz AJ, Portoghese PS (November 2014). “Targeting putative mu opioid/metabotropic glutamate receptor-5 heteromers produces potent antinociception in a chronic murine bone cancer model”. 《European Journal of Pharmacology》 743: 48–52. doi:10.1016/j.ejphar.2014.09.008. PMC 4259840. PMID 25239072.
Abrusan G, Marsh JA (2019). “Ligand Binding Site Structure Shapes Folding, Assembly and Degradation of Homomeric Protein Complexes.”. 《Journal of Molecular Biology》 431 (19): 3871–3888. doi:10.1016/j.jmb.2019.07.014. PMC 6739599. PMID 31306664.
Abrusan G, Marsh JA (2018). “Ligand Binding Site Structure Influences the Evolution of Protein Complex Function and Topology.”. 《Cell Reports》 22 (12): 3265–3276. doi:10.1016/j.celrep.2018.02.085. PMC 5873459. PMID 29562182.
Abrusan G, Marsh JA (2019). “Ligand-Binding-Site Structure Shapes Allosteric Signal Transduction and the Evolution of Allostery in Protein Complexes.”. 《Molecular Biology and Evolution》 36 (8): 1711–1727. doi:10.1093/molbev/msz093. PMC 6657754. PMID 31004156.
Welsch ME, Snyder SA, Stockwell BR (June 2010). “Privileged scaffolds for library design and drug discovery”. 《Current Opinion in Chemical Biology》 14 (3): 347–61. doi:10.1016/j.cbpa.2010.02.018. PMC 2908274. PMID 20303320.
Kombarov R, Altieri A, Genis D, Kirpichenok M, Kochubey V, Rakitina N, Titarenko Z (February 2010). “BioCores: identification of a drug/natural product-based privileged structural motif for small-molecule lead discovery”. 《Molecular Diversity》 14 (1): 193–200. doi:10.1007/s11030-009-9157-5. PMID 19468851. S2CID 23331540.

doi.org

https://doi.org/10.1093/oso/9780199744121.003.0006

handle.net

hdl.handle.net

Busnelli M, Kleinau G, Muttenthaler M, Stoev S, Manning M, Bibic L, Howell LA, McCormick PJ, Di Lascio S, Braida D, Sala M, Rovati GE, Bellini T, Chini B (August 2016). “Design and Characterization of Superpotent Bivalent Ligands Targeting Oxytocin Receptor Dimers via a Channel-Like Structure”. 《Journal of Medicinal Chemistry》 59 (15): 7152–7166. doi:10.1021/acs.jmedchem.6b00564. hdl:2434/430357. PMID 27420737.

nih.gov

ncbi.nlm.nih.gov

“A hot road to new drugs”. 《Phys.org》. 2010년 2월 24일.
Wienken CJ, Baaske P, Rothbauer U, Braun D, Duhr S (October 2010). “Protein-binding assays in biological liquids using microscale thermophoresis”. 《Nature Communications》 1 (7): 100. Bibcode:2010NatCo...1..100W. doi:10.1038/ncomms1093. PMID 20981028.
Cabanos, C; Wang, M; Han, X; Hansen, SB (2017년 8월 8일). “A Soluble Fluorescent Binding Assay Reveals PIP₂ Antagonism of TREK-1 Channels.”. 《Cell Reports》 20 (6): 1287–1294. doi:10.1016/j.celrep.2017.07.034. PMC 5586213. PMID 28793254.
Matera, Carlo; Pucci, Luca; Fiorentini, Chiara; Fucile, Sergio; Missale, Cristina; Grazioso, Giovanni; Clementi, Francesco; Zoli, Michele; De Amici, Marco (2015년 8월 28일). “Bifunctional compounds targeting both D2 and non-α7 nACh receptors: Design, synthesis and pharmacological characterization”. 《European Journal of Medicinal Chemistry》 101: 367–383. doi:10.1016/j.ejmech.2015.06.039. PMID 26164842.
Matera, Carlo; Flammini, Lisa; Quadri, Marta; Vivo, Valentina; Ballabeni, Vigilio; Holzgrabe, Ulrike; Mohr, Klaus; De Amici, Marco; Barocelli, Elisabetta (2014년 3월 21일). “Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: Synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity”. 《European Journal of Medicinal Chemistry》 75: 222–232. doi:10.1016/j.ejmech.2014.01.032. PMID 24534538.
Erez M, Takemori AE, Portoghese PS (July 1982). “Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites”. 《Journal of Medicinal Chemistry》 25 (7): 847–849. doi:10.1021/jm00349a016. PMID 7108900.
Portoghese PS, Ronsisvalle G, Larson DL, Yim CB, Sayre LM, Takemori AE (1982). “Opioid agonist and antagonist bivalent ligands as receptor probes”. 《Life Sciences》 31 (12–13): 1283–1286. doi:10.1016/0024-3205(82)90362-9. PMID 6292615.
Portoghese PS, Akgün E, Lunzer MM (January 2017). “Heteromer Induction: An Approach to Unique Pharmacology?”. 《ACS Chemical Neuroscience》 8 (3): 426–428. doi:10.1021/acschemneuro.7b00002. PMID 28139906.
Blum JJ, Conn PM (December 1982). “Gonadotropin-releasing hormone stimulation of luteinizing hormone release: A ligand-receptor-effector model”. 《Proceedings of the National Academy of Sciences of the United States of America》 79 (23): 7307–7311. Bibcode:1982PNAS...79.7307B. doi:10.1073/pnas.79.23.7307. JSTOR 13076. PMC 347328. PMID 6296828.
Conn PM, Rogers DC, Stewart JM, Niedel J, Sheffield T (April 1982). “Conversion of a gonadotropin-releasing hormone antagonist to an agonist”. 《Nature》 296 (5858): 653–655. Bibcode:1982Natur.296..653C. doi:10.1038/296653a0. PMID 6280058. S2CID 4303982.
Nimczick M, Pemp D, Darras FH, Chen X, Heilmann J, Decker M (August 2014). “Synthesis and biological evaluation of bivalent cannabinoid receptor ligands based on hCB₂R selective benzimidazoles reveal unexpected intrinsic properties”. 《Bioorganic & Medicinal Chemistry》 22 (15): 3938–3946. doi:10.1016/j.bmc.2014.06.008. PMID 24984935.
Russo O, Berthouze M, Giner M, Soulier JL, Rivail L, Sicsic S, Lezoualc'h F, Jockers R, Berque-Bestel I (September 2007). “Synthesis of specific bivalent probes that functionally interact with 5-HT(4) receptor dimers”. 《Journal of Medicinal Chemistry》 50 (18): 4482–4492. doi:10.1021/jm070552t. PMID 17676726.
Soulier JL, Russo O, Giner M, Rivail L, Berthouze M, Ongeri S, Maigret B, Fischmeister R, Lezoualc'h F, Sicsic S, Berque-Bestel I (October 2005). “Design and synthesis of specific probes for human 5-HT4 receptor dimerization studies” (PDF). 《Journal of Medicinal Chemistry》 48 (20): 6220–6228. doi:10.1021/jm050234z. PMID 16190749.
Busnelli M, Kleinau G, Muttenthaler M, Stoev S, Manning M, Bibic L, Howell LA, McCormick PJ, Di Lascio S, Braida D, Sala M, Rovati GE, Bellini T, Chini B (August 2016). “Design and Characterization of Superpotent Bivalent Ligands Targeting Oxytocin Receptor Dimers via a Channel-Like Structure”. 《Journal of Medicinal Chemistry》 59 (15): 7152–7166. doi:10.1021/acs.jmedchem.6b00564. hdl:2434/430357. PMID 27420737.
Lensing CJ, Adank DN, Wilber SL, Freeman KT, Schnell SM, Speth RC, Zarth AT, Haskell-Luevano C (February 2017). “A Direct in Vivo Comparison of the Melanocortin Monovalent Agonist Ac-His-DPhe-Arg-Trp-NH2 versus the Bivalent Agonist Ac-His-DPhe-Arg-Trp-PEDG20-His-DPhe-Arg-Trp-NH2: A Bivalent Advantage”. 《ACS Chemical Neuroscience》 8 (6): 1262–1278. doi:10.1021/acschemneuro.6b00399. PMC 5679024. PMID 28128928.
Xu L, Josan JS, Vagner J, Caplan MR, Hruby VJ, Mash EA, Lynch RM, Morse DL, Gillies RJ (December 2012). “Heterobivalent ligands target cell-surface receptor combinations in vivo”. 《Proceedings of the National Academy of Sciences of the United States of America》 109 (52): 21295–21300. Bibcode:2012PNAS..10921295X. doi:10.1073/pnas.1211762109. JSTOR 42553664. PMC 3535626. PMID 23236171.
Lensing CJ, Freeman KT, Schnell SM, Adank DN, Speth RC, Haskell-Luevano C (April 2016). “An in Vitro and in Vivo Investigation of Bivalent Ligands That Display Preferential Binding and Functional Activity for Different Melanocortin Receptor Homodimers”. 《Journal of Medicinal Chemistry》 59 (7): 3112–3128. doi:10.1021/acs.jmedchem.5b01894. PMC 5679017. PMID 26959173.
Shonberg J, Scammells PJ, Capuano B (June 2011). “Design strategies for bivalent ligands targeting GPCRs”. 《ChemMedChem》 6 (6): 963–974. doi:10.1002/cmdc.201100101. PMID 21520422. S2CID 10561038.
Berque-Bestel I, Lezoualc'h F, Jockers R (December 2008). “Bivalent ligands as specific pharmacological tools for G protein-coupled receptor dimers”. 《Current Drug Discovery Technologies》 5 (4): 312–318. doi:10.2174/157016308786733591. PMID 19075611.
Akgün E, Javed MI, Lunzer MM, Powers MD, Sham YY, Watanabe Y, Portoghese PS (November 2015). “Inhibition of Inflammatory and Neuropathic Pain by Targeting a Mu Opioid Receptor/Chemokine Receptor5 Heteromer (MOR-CCR5)”. 《Journal of Medicinal Chemistry》 58 (21): 8647–8657. doi:10.1021/acs.jmedchem.5b01245. PMC 5055304. PMID 26451468.
Daniels DJ, Lenard NR, Etienne CL, Law PY, Roerig SC, Portoghese PS (December 2005). “Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series”. 《Proceedings of the National Academy of Sciences of the United States of America》 102 (52): 19208–19213. Bibcode:2005PNAS..10219208D. doi:10.1073/pnas.0506627102. JSTOR 4152590. PMC 1323165. PMID 16365317.
Smeester BA, Lunzer MM, Akgün E, Beitz AJ, Portoghese PS (November 2014). “Targeting putative mu opioid/metabotropic glutamate receptor-5 heteromers produces potent antinociception in a chronic murine bone cancer model”. 《European Journal of Pharmacology》 743: 48–52. doi:10.1016/j.ejphar.2014.09.008. PMC 4259840. PMID 25239072.
Abrusan G, Marsh JA (2019). “Ligand Binding Site Structure Shapes Folding, Assembly and Degradation of Homomeric Protein Complexes.”. 《Journal of Molecular Biology》 431 (19): 3871–3888. doi:10.1016/j.jmb.2019.07.014. PMC 6739599. PMID 31306664.
Abrusan G, Marsh JA (2018). “Ligand Binding Site Structure Influences the Evolution of Protein Complex Function and Topology.”. 《Cell Reports》 22 (12): 3265–3276. doi:10.1016/j.celrep.2018.02.085. PMC 5873459. PMID 29562182.
Abrusan G, Marsh JA (2019). “Ligand-Binding-Site Structure Shapes Allosteric Signal Transduction and the Evolution of Allostery in Protein Complexes.”. 《Molecular Biology and Evolution》 36 (8): 1711–1727. doi:10.1093/molbev/msz093. PMC 6657754. PMID 31004156.
Welsch ME, Snyder SA, Stockwell BR (June 2010). “Privileged scaffolds for library design and drug discovery”. 《Current Opinion in Chemical Biology》 14 (3): 347–61. doi:10.1016/j.cbpa.2010.02.018. PMC 2908274. PMID 20303320.
Kombarov R, Altieri A, Genis D, Kirpichenok M, Kochubey V, Rakitina N, Titarenko Z (February 2010). “BioCores: identification of a drug/natural product-based privileged structural motif for small-molecule lead discovery”. 《Molecular Diversity》 14 (1): 193–200. doi:10.1007/s11030-009-9157-5. PMID 19468851. S2CID 23331540.

physorg.com

“A hot road to new drugs”. 《Phys.org》. 2010년 2월 24일.

semanticscholar.org

api.semanticscholar.org

Conn PM, Rogers DC, Stewart JM, Niedel J, Sheffield T (April 1982). “Conversion of a gonadotropin-releasing hormone antagonist to an agonist”. 《Nature》 296 (5858): 653–655. Bibcode:1982Natur.296..653C. doi:10.1038/296653a0. PMID 6280058. S2CID 4303982.

Shonberg J, Scammells PJ, Capuano B (June 2011). “Design strategies for bivalent ligands targeting GPCRs”. 《ChemMedChem》 6 (6): 963–974. doi:10.1002/cmdc.201100101. PMID 21520422. S2CID 10561038.

Kombarov R, Altieri A, Genis D, Kirpichenok M, Kochubey V, Rakitina N, Titarenko Z (February 2010). “BioCores: identification of a drug/natural product-based privileged structural motif for small-molecule lead discovery”. 《Molecular Diversity》 14 (1): 193–200. doi:10.1007/s11030-009-9157-5. PMID 19468851. S2CID 23331540.

리간드 (생화학) (Korean Wikipedia)

archives-ouvertes.fr

hal.archives-ouvertes.fr

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books.google.com

doi.org

dx.doi.org

doi.org

graphpad.com

handle.net

hdl.handle.net

harvard.edu

adsabs.harvard.edu

jstor.org

nih.gov

ncbi.nlm.nih.gov

physorg.com

sciencesnail.com

semanticscholar.org

api.semanticscholar.org

ufl.edu

clesm.mae.ufl.edu

web.archive.org