Klaus W.K.W.BeyenbachKlaus W.K.W., HelmutH.WieczorekHelmutH., The V-type H+ ATPase: molecular structure and function, physiological roles and regulation, „The Journal of Experimental Biology”, 209 (4), 2006, s. 577–589, DOI: 10.1242/jeb.02014, PMID: 16449553 [dostęp 2021-04-26], Cytat: The V-type H+ ATPase is now thought to be present in virtually every eukaryotic cell. The proton pump occupies intracellular membranes such as those of clathrin-coated vesicles, synaptic vesicles, endosomes, storage vesicles, Golgi vesicles, secretory vesicles, lysosomes and their partner organelle in plants and fungi, the central vacuole (Stevens and Forgac, 1997). Best known are the contributions made by the V-type H+ ATPase to the acidification of intracellular compartments. In lysosomes and in vacuoles of plants and fungi, a pH of about 5 serves the breakdown of macromolecules by up to 40 types of acid hydrolases including proteases, glycosidases, lipases, nucleases and phosphatases.(ang.).
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Klaus W.K.W.BeyenbachKlaus W.K.W., HelmutH.WieczorekHelmutH., The V-type H+ ATPase: molecular structure and function, physiological roles and regulation, „The Journal of Experimental Biology”, 209 (4), 2006, s. 577–589, DOI: 10.1242/jeb.02014, PMID: 16449553 [dostęp 2021-04-26], Cytat: The V-type H+ ATPase is now thought to be present in virtually every eukaryotic cell. The proton pump occupies intracellular membranes such as those of clathrin-coated vesicles, synaptic vesicles, endosomes, storage vesicles, Golgi vesicles, secretory vesicles, lysosomes and their partner organelle in plants and fungi, the central vacuole (Stevens and Forgac, 1997). Best known are the contributions made by the V-type H+ ATPase to the acidification of intracellular compartments. In lysosomes and in vacuoles of plants and fungi, a pH of about 5 serves the breakdown of macromolecules by up to 40 types of acid hydrolases including proteases, glycosidases, lipases, nucleases and phosphatases.(ang.).
