Strauss JS, Krowchuk DP, Leyden JJ, Lucky AW, Shalita AR, Siegfried EC, Thiboutot DM, Van Voorhees AS, Beutner KA, Sieck CK, Bhushan R (abril de 2007). «Guidelines of care for acne vulgaris management». Journal of the American Academy of Dermatology. 56 (4): 651–63. PMID17276540. doi:10.1016/j.jaad.2006.08.048
Sehgal VN, Srivastava G, Sardana K (junho de 2006). «Isotretinoin--unapproved indications/uses and dosage: a physician's reference». International Journal of Dermatology. 45 (6): 772–7. PMID16796650. doi:10.1111/j.1365-4632.2006.02830.x
David M, Hodak E, Lowe NJ (1988). «Adverse effects of retinoids». Medical Toxicology and Adverse Drug Experience. 3 (4): 273–88. PMID3054426. doi:10.1007/bf03259940
DiGiovanna JJ (novembro de 2001). «Isotretinoin effects on bone». Journal of the American Academy of Dermatology. 45 (5): S176-82. PMID11606950. doi:10.1067/mjd.2001.113721
Ellis CN, Madison KC, Pennes DR, Martel W, Voorhees JJ (1984). «Isotretinoin therapy is associated with early skeletal radiographic changes». Journal of the American Academy of Dermatology. 10 (6): 1024–9. PMID6588057. doi:10.1016/S0190-9622(84)80329-1
Lambert RW, Smith RE (março de 1989). «Effects of 13-cis-retinoic acid on the hamster meibomian gland». The Journal of Investigative Dermatology. 92 (3): 321–5. PMID2918239. doi:10.1111/1523-1747.ep12277122
Fraunfelder FT, Fraunfelder FW, Edwards R (setembro de 2001). «Ocular side effects possibly associated with isotretinoin usage». American Journal of Ophthalmology. 132 (3): 299–305. PMID11530040. doi:10.1016/S0002-9394(01)01024-8
Borovaya A, Olisova O, Ruzicka T, Sárdy M (setembro de 2013). «Does isotretinoin therapy of acne cure or cause depression?». International Journal of Dermatology. 52 (9): 1040–52. PMID23962262. doi:10.1111/ijd.12169
Goodfield MJ, Cox NH, Bowser A, McMillan JC, Millard LG, Simpson NB, Ormerod AD (junho de 2010). «Advice on the safe introduction and continued use of isotretinoin in acne in the U.K. 2010». The British Journal of Dermatology. 162 (6): 1172–9. PMID21250961. doi:10.1111/j.1365-2133.2010.09836.x
Rowe C, Spelman L, Oziemski M, Ryan A, Manoharan S, Wilson P, Daubney M, Scott J (maio de 2014). «Isotretinoin and mental health in adolescents: Australian consensus». The Australasian Journal of Dermatology (Review). 55 (2): 162–7. PMID24283385. doi:10.1111/ajd.12117
Goodman AB (março de 1994). «Retinoid dysregulation as a cause of schizophrenia». The American Journal of Psychiatry. 151 (3): 452–3. PMID8109664. doi:10.1176/ajp.151.3.452b
Goodman AB (maio de 1996). «Congenital anomalies in relatives of schizophrenic probands may indicate a retinoid pathology». Schizophrenia Research. 19 (2–3): 163–70. PMID8789914. doi:10.1016/0920-9964(96)88523-9
Goodman AB (julho de 2005). «Microarray results suggest altered transport and lowered synthesis of retinoic acid in schizophrenia». Molecular Psychiatry. 10 (7): 620–1. PMID15838536. doi:10.1038/sj.mp.4001668
Lowenstein EB, Lowenstein EJ (2011). «Isotretinoin systemic therapy and the shadow cast upon dermatology's downtrodden hero». Clinics in Dermatology. 29 (6): 652–61. PMID22014987. doi:10.1016/j.clindermatol.2011.08.026
Kremer I, Gaton DD, David M, Gaton E, Shapiro A (1994). «Toxic effects of systemic retinoids on meibomian glands». Ophthalmic Research. 26 (2): 124–8. PMID8196934. doi:10.1159/000267402
Griffin JN, Pinali D, Olds K, Lu N, Appleby L, Doan L, Lane MA (novembro de 2010). «13-Cis-retinoic acid decreases hypothalamic cell number in vitro». Neuroscience Research. 68 (3): 185–90. PMID20708044. doi:10.1016/j.neures.2010.08.003
Sakai Y, Crandall JE, Brodsky J, McCaffery P (junho de 2004). «13-cis Retinoic acid (accutane) suppresses hippocampal cell survival in mice». Annals of the New York Academy of Sciences. 1021 (1): 436–40. Bibcode:2004NYASA1021..436S. PMID15251924. doi:10.1196/annals.1308.059
Nelson AM, Gilliland KL, Cong Z, Thiboutot DM (outubro de 2006). «13-cis Retinoic acid induces apoptosis and cell cycle arrest in human SEB-1 sebocytes». The Journal of Investigative Dermatology. 126 (10): 2178–89. PMID16575387. doi:10.1038/sj.jid.5700289
Wachter K (2009). «Isotretinoin's Mechanism of Action Explored». Skin & Allergy News. 40 (11). 32 páginas. doi:10.1016/S0037-6337(09)70553-4
Peck GL, Olsen TG, Yoder FW, Strauss JS, Downing DT, Pandya M, Butkus D, Arnaud-Battandier J (fevereiro de 1979). «Prolonged remissions of cystic and conglobate acne with 13-cis-retinoic acid». The New England Journal of Medicine. 300 (7): 329–33. PMID153472. doi:10.1056/NEJM197902153000701
Shalita A (2001). «The integral role of topical and oral retinoids in the early treatment of acne». Journal of the European Academy of Dermatology and Venereology. 15: 43–9. PMID11843233. doi:10.1046/j.0926-9959.2001.00012.x
Toyoda M, Nakamura M, Makino T, Kagoura M, Morohashi M (junho de 2002). «Sebaceous glands in acne patients express high levels of neutral endopeptidase». Experimental Dermatology. 11 (3): 241–7. PMID12102663. doi:10.1034/j.1600-0625.2002.110307.x
Wysowski DK, Swartz L (maio de 2005). «Relationship between headache and depression in users of isotretinoin». Archives of Dermatology (em inglês). 141 (5): 640–1. PMID15897395. doi:10.1001/archderm.141.5.640
Ng CH, Schweitzer I (fevereiro de 2003). «The association between depression and isotretinoin use in acne». The Australian and New Zealand Journal of Psychiatry (em inglês). 37 (1): 78–84. PMID12534661. doi:10.1046/j.1440-1614.2003.01111.x
Sakai Y, Crandall JE, Brodsky J, McCaffery P (junho de 2004). «13-cis Retinoic acid (accutane) suppresses hippocampal cell survival in mice». Annals of the New York Academy of Sciences. 1021 (1): 436–40. Bibcode:2004NYASA1021..436S. PMID15251924. doi:10.1196/annals.1308.059
Strauss JS, Krowchuk DP, Leyden JJ, Lucky AW, Shalita AR, Siegfried EC, Thiboutot DM, Van Voorhees AS, Beutner KA, Sieck CK, Bhushan R (abril de 2007). «Guidelines of care for acne vulgaris management». Journal of the American Academy of Dermatology. 56 (4): 651–63. PMID17276540. doi:10.1016/j.jaad.2006.08.048
Sehgal VN, Srivastava G, Sardana K (junho de 2006). «Isotretinoin--unapproved indications/uses and dosage: a physician's reference». International Journal of Dermatology. 45 (6): 772–7. PMID16796650. doi:10.1111/j.1365-4632.2006.02830.x
David M, Hodak E, Lowe NJ (1988). «Adverse effects of retinoids». Medical Toxicology and Adverse Drug Experience. 3 (4): 273–88. PMID3054426. doi:10.1007/bf03259940
DiGiovanna JJ (novembro de 2001). «Isotretinoin effects on bone». Journal of the American Academy of Dermatology. 45 (5): S176-82. PMID11606950. doi:10.1067/mjd.2001.113721
Ellis CN, Madison KC, Pennes DR, Martel W, Voorhees JJ (1984). «Isotretinoin therapy is associated with early skeletal radiographic changes». Journal of the American Academy of Dermatology. 10 (6): 1024–9. PMID6588057. doi:10.1016/S0190-9622(84)80329-1
Lambert RW, Smith RE (março de 1989). «Effects of 13-cis-retinoic acid on the hamster meibomian gland». The Journal of Investigative Dermatology. 92 (3): 321–5. PMID2918239. doi:10.1111/1523-1747.ep12277122
Fraunfelder FT, Fraunfelder FW, Edwards R (setembro de 2001). «Ocular side effects possibly associated with isotretinoin usage». American Journal of Ophthalmology. 132 (3): 299–305. PMID11530040. doi:10.1016/S0002-9394(01)01024-8
Scheinfeld N, Bangalore S (maio de 2006). «Facial edema induced by isotretinoin use: a case and a review of the side effects of isotretinoin». Journal of Drugs in Dermatology. 5 (5): 467–8. PMID16703787
Borovaya A, Olisova O, Ruzicka T, Sárdy M (setembro de 2013). «Does isotretinoin therapy of acne cure or cause depression?». International Journal of Dermatology. 52 (9): 1040–52. PMID23962262. doi:10.1111/ijd.12169
Goodfield MJ, Cox NH, Bowser A, McMillan JC, Millard LG, Simpson NB, Ormerod AD (junho de 2010). «Advice on the safe introduction and continued use of isotretinoin in acne in the U.K. 2010». The British Journal of Dermatology. 162 (6): 1172–9. PMID21250961. doi:10.1111/j.1365-2133.2010.09836.x
Rowe C, Spelman L, Oziemski M, Ryan A, Manoharan S, Wilson P, Daubney M, Scott J (maio de 2014). «Isotretinoin and mental health in adolescents: Australian consensus». The Australasian Journal of Dermatology (Review). 55 (2): 162–7. PMID24283385. doi:10.1111/ajd.12117
Goodman AB (março de 1994). «Retinoid dysregulation as a cause of schizophrenia». The American Journal of Psychiatry. 151 (3): 452–3. PMID8109664. doi:10.1176/ajp.151.3.452b
Goodman AB (maio de 1996). «Congenital anomalies in relatives of schizophrenic probands may indicate a retinoid pathology». Schizophrenia Research. 19 (2–3): 163–70. PMID8789914. doi:10.1016/0920-9964(96)88523-9
Goodman AB (julho de 2005). «Microarray results suggest altered transport and lowered synthesis of retinoic acid in schizophrenia». Molecular Psychiatry. 10 (7): 620–1. PMID15838536. doi:10.1038/sj.mp.4001668
Lowenstein EB, Lowenstein EJ (2011). «Isotretinoin systemic therapy and the shadow cast upon dermatology's downtrodden hero». Clinics in Dermatology. 29 (6): 652–61. PMID22014987. doi:10.1016/j.clindermatol.2011.08.026
Kremer I, Gaton DD, David M, Gaton E, Shapiro A (1994). «Toxic effects of systemic retinoids on meibomian glands». Ophthalmic Research. 26 (2): 124–8. PMID8196934. doi:10.1159/000267402
Griffin JN, Pinali D, Olds K, Lu N, Appleby L, Doan L, Lane MA (novembro de 2010). «13-Cis-retinoic acid decreases hypothalamic cell number in vitro». Neuroscience Research. 68 (3): 185–90. PMID20708044. doi:10.1016/j.neures.2010.08.003
Sakai Y, Crandall JE, Brodsky J, McCaffery P (junho de 2004). «13-cis Retinoic acid (accutane) suppresses hippocampal cell survival in mice». Annals of the New York Academy of Sciences. 1021 (1): 436–40. Bibcode:2004NYASA1021..436S. PMID15251924. doi:10.1196/annals.1308.059
Nelson AM, Gilliland KL, Cong Z, Thiboutot DM (outubro de 2006). «13-cis Retinoic acid induces apoptosis and cell cycle arrest in human SEB-1 sebocytes». The Journal of Investigative Dermatology. 126 (10): 2178–89. PMID16575387. doi:10.1038/sj.jid.5700289
Peck GL, Olsen TG, Yoder FW, Strauss JS, Downing DT, Pandya M, Butkus D, Arnaud-Battandier J (fevereiro de 1979). «Prolonged remissions of cystic and conglobate acne with 13-cis-retinoic acid». The New England Journal of Medicine. 300 (7): 329–33. PMID153472. doi:10.1056/NEJM197902153000701
Shalita A (2001). «The integral role of topical and oral retinoids in the early treatment of acne». Journal of the European Academy of Dermatology and Venereology. 15: 43–9. PMID11843233. doi:10.1046/j.0926-9959.2001.00012.x
Toyoda M, Nakamura M, Makino T, Kagoura M, Morohashi M (junho de 2002). «Sebaceous glands in acne patients express high levels of neutral endopeptidase». Experimental Dermatology. 11 (3): 241–7. PMID12102663. doi:10.1034/j.1600-0625.2002.110307.x
Wysowski DK, Swartz L (maio de 2005). «Relationship between headache and depression in users of isotretinoin». Archives of Dermatology (em inglês). 141 (5): 640–1. PMID15897395. doi:10.1001/archderm.141.5.640
Ng CH, Schweitzer I (fevereiro de 2003). «The association between depression and isotretinoin use in acne». The Australian and New Zealand Journal of Psychiatry (em inglês). 37 (1): 78–84. PMID12534661. doi:10.1046/j.1440-1614.2003.01111.x