Clayton T, Chen JL, Ernst M, Richter L, Cromer BA, Morton CJ, Ng H, Kaczorowski CC, Helmstetter FJ, Furtmüller R, Ecker G, Parker MW, Sieghart W, Cook JM (2007). «An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models». Curr. Med. Chem. 14 (26): 2755–75. PMID18045122. doi:10.2174/092986707782360097 !CS1 manut: Nomes múltiplos: lista de autores (link)
Campagna-Slater V, Weaver DF (2007). «Molecular modelling of the GABAA ion channel protein». J. Mol. Graph. Model. 25 (5): 721–30. PMID16877018. doi:10.1016/j.jmgm.2006.06.001
Sancar F, Ericksen SS, Kucken AM, Teissére JA, Czajkowski C (2007). «Structural determinants for high-affinity zolpidem binding to GABA-A receptors». Mol. Pharmacol. 71 (1): 38–46. PMID17012619. doi:10.1124/mol.106.029595 !CS1 manut: Nomes múltiplos: lista de autores (link)
Chen K, Li HZ, Ye N, Zhang J, Wang JJ (2005). «Role of GABAB receptors in GABA and baclofen-induced inhibition of adult rat cerebellar interpositus nucleus neurons in vitro». Brain Res Bull. 67 (4): 310–8. PMID16182939. doi:10.1016/j.brainresbull.2005.07.004 !CS1 manut: Nomes múltiplos: lista de autores (link)
Cossart R, Bernard C, Ben-Ari Y (2005). «Multiple facets of GABAergic neurons and synapses: multiple fates of GABA signalling in epilepsies». Trends Neurosci. 28 (2): 108–15. PMID15667934. doi:10.1016/j.tins.2004.11.011 !CS1 manut: Nomes múltiplos: lista de autores (link)
Colquhoun D, Sivilotti LG (2004). «Function and structure in glycine receptors and some of their relatives». Trends Neurosci. 27 (6): 337–44. PMID15165738. doi:10.1016/j.tins.2004.04.010
(a) Herd MB, Belelli D, Lambert JJ (2007). «Neurosteroid modulation of synaptic and extrasynaptic GABAA receptors». Pharmacology & Therapeutics. 116. 20 páginas. PMID17531325. doi:10.1016/j.pharmthera.2007.03.007 !CS1 manut: Nomes múltiplos: lista de autores (link); (b) Hosie AM, Wilkins ME, da Silva HM, Smart TG (2006). «Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites». Nature. 444 (7118): 486–9. PMID17108970. doi:10.1038/nature05324 !CS1 manut: Nomes múltiplos: lista de autores (link); (c) Agís-Balboa RC, Pinna G, Zhubi A, Maloku E, Veldic M, Costa E, Guidotti A (2006). «Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis». Proc. Natl. Acad. Sci. U.S.A. 103 (39): 14602–7. PMID16984997. doi:10.1073/pnas.0606544103 !CS1 manut: Nomes múltiplos: lista de autores (link); (d) Akk G, Shu HJ, Wang C, Steinbach JH, Zorumski CF, Covey DF, Mennerick S (2005). «Neurosteroid access to the GABAA receptor». J. Neurosci. 25 (50): 11605–13. PMID16354918. doi:10.1523/JNEUROSCI.4173-05.2005 !CS1 manut: Nomes múltiplos: lista de autores (link); (e) Belelli D, Lambert JJ (2005). «Neurosteroids: endogenous regulators of the GABAA receptor». Nat. Rev. Neurosci. 6 (7): 565–75. PMID15959466. doi:10.1038/nrn1703; (f) Pinna G, Costa E, Guidotti A (2006). «Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake». Psychopharmacology (Berl.). 186 (3): 362–72. PMID16432684. doi:10.1007/s00213-005-0213-2 !CS1 manut: Nomes múltiplos: lista de autores (link); (g) Dubrovsky BO (2005). «Steroids, neuroactive steroids and neurosteroids in psychopathology». Prog. Neuropsychopharmacol. Biol. Psychiatry. 29 (2): 169–92. PMID15694225. doi:10.1016/j.pnpbp.2004.11.001; (h) Mellon SH, Griffin LD (2002). «Neurosteroids: biochemistry and clinical significance». Trends Endocrinol. Metab. 13 (1): 35–43. PMID11750861. doi:10.1016/S1043-2760(01)00503-3; (i) Puia G, Santi MR, Vicini S, Pritchett DB, Purdy RH, Paul SM, Seeburg PH, Costa E (1990). «Neurosteroids act on recombinant human GABAA receptors». Neuron. 4 (5): 759–65. PMID2160838 !CS1 manut: Nomes múltiplos: lista de autores (link); (j) Majewska MD, Harrison NL, Schwartz RD, Barker JL, Paul SM (1986). «Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor». Science. 232 (4753): 1004–7. PMID2422758. doi:10.1126/science.2422758 !CS1 manut: Nomes múltiplos: lista de autores (link)
Dawson GR, Maubach KA, Collinson N, Cobain M, Everitt BJ, MacLeod AM, Choudhury HI, McDonald LM, Pillai G, Rycroft W, Smith AJ, Sternfeld F, Tattersall FD, Wafford KA, Reynolds DS, Seabrook GR, Atack JR (2006). «An inverse agonist selective for alpha5 subunit-containing GABAA receptors enhances cognition». J. Pharmacol. Exp. Ther. 316 (3): 1335–45. PMID16326923. doi:10.1124/jpet.105.092320 !CS1 manut: Nomes múltiplos: lista de autores (link)
Sigel E (2002). «Mapping of the benzodiazepine recognition site on GABAA receptors». Curr Top Med Chem. 2 (8): 833–9. PMID12171574. doi:10.2174/1568026023393444
Akabas MH (2004). «GABAA receptor structure-function studies: a reexamination in light of new acetylcholine receptor structures». Int. Rev. Neurobiol. 62: 1–43. PMID15530567. doi:10.1016/S0074-7742(04)62001-0
Derry JM, Dunn SM, Davies M (2004). «Identification of a residue in the gamma-aminobutyric acid type A receptor alpha subunit that differentially affects diazepam-sensitive and -insensitive benzodiazepine site binding». J. Neurochem. 88 (6): 1431–8. PMID15009644. doi:10.1046/j.1471-4159.2003.02264.x !CS1 manut: Nomes múltiplos: lista de autores (link)
Hanson SM, Czajkowski C (2008). «Structural mechanisms underlying benzodiazepine modulation of the GABA(A) receptor». J. Neurosci. 28 (13): 3490–9. PMID18367615. doi:10.1523/JNEUROSCI.5727-07.2008
Twyman RE, Rogers CJ, Macdonald RL (1989). «Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbital». Ann. Neurol. 25 (3): 213–20. PMID2471436. doi:10.1002/ana.410250302 !CS1 manut: Nomes múltiplos: lista de autores (link)
nih.gov
ncbi.nlm.nih.gov
Clayton T, Chen JL, Ernst M, Richter L, Cromer BA, Morton CJ, Ng H, Kaczorowski CC, Helmstetter FJ, Furtmüller R, Ecker G, Parker MW, Sieghart W, Cook JM (2007). «An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models». Curr. Med. Chem. 14 (26): 2755–75. PMID18045122. doi:10.2174/092986707782360097 !CS1 manut: Nomes múltiplos: lista de autores (link)
Campagna-Slater V, Weaver DF (2007). «Molecular modelling of the GABAA ion channel protein». J. Mol. Graph. Model. 25 (5): 721–30. PMID16877018. doi:10.1016/j.jmgm.2006.06.001
Sancar F, Ericksen SS, Kucken AM, Teissére JA, Czajkowski C (2007). «Structural determinants for high-affinity zolpidem binding to GABA-A receptors». Mol. Pharmacol. 71 (1): 38–46. PMID17012619. doi:10.1124/mol.106.029595 !CS1 manut: Nomes múltiplos: lista de autores (link)
Chen K, Li HZ, Ye N, Zhang J, Wang JJ (2005). «Role of GABAB receptors in GABA and baclofen-induced inhibition of adult rat cerebellar interpositus nucleus neurons in vitro». Brain Res Bull. 67 (4): 310–8. PMID16182939. doi:10.1016/j.brainresbull.2005.07.004 !CS1 manut: Nomes múltiplos: lista de autores (link)
Cossart R, Bernard C, Ben-Ari Y (2005). «Multiple facets of GABAergic neurons and synapses: multiple fates of GABA signalling in epilepsies». Trends Neurosci. 28 (2): 108–15. PMID15667934. doi:10.1016/j.tins.2004.11.011 !CS1 manut: Nomes múltiplos: lista de autores (link)
Colquhoun D, Sivilotti LG (2004). «Function and structure in glycine receptors and some of their relatives». Trends Neurosci. 27 (6): 337–44. PMID15165738. doi:10.1016/j.tins.2004.04.010
(a) Herd MB, Belelli D, Lambert JJ (2007). «Neurosteroid modulation of synaptic and extrasynaptic GABAA receptors». Pharmacology & Therapeutics. 116. 20 páginas. PMID17531325. doi:10.1016/j.pharmthera.2007.03.007 !CS1 manut: Nomes múltiplos: lista de autores (link); (b) Hosie AM, Wilkins ME, da Silva HM, Smart TG (2006). «Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites». Nature. 444 (7118): 486–9. PMID17108970. doi:10.1038/nature05324 !CS1 manut: Nomes múltiplos: lista de autores (link); (c) Agís-Balboa RC, Pinna G, Zhubi A, Maloku E, Veldic M, Costa E, Guidotti A (2006). «Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis». Proc. Natl. Acad. Sci. U.S.A. 103 (39): 14602–7. PMID16984997. doi:10.1073/pnas.0606544103 !CS1 manut: Nomes múltiplos: lista de autores (link); (d) Akk G, Shu HJ, Wang C, Steinbach JH, Zorumski CF, Covey DF, Mennerick S (2005). «Neurosteroid access to the GABAA receptor». J. Neurosci. 25 (50): 11605–13. PMID16354918. doi:10.1523/JNEUROSCI.4173-05.2005 !CS1 manut: Nomes múltiplos: lista de autores (link); (e) Belelli D, Lambert JJ (2005). «Neurosteroids: endogenous regulators of the GABAA receptor». Nat. Rev. Neurosci. 6 (7): 565–75. PMID15959466. doi:10.1038/nrn1703; (f) Pinna G, Costa E, Guidotti A (2006). «Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake». Psychopharmacology (Berl.). 186 (3): 362–72. PMID16432684. doi:10.1007/s00213-005-0213-2 !CS1 manut: Nomes múltiplos: lista de autores (link); (g) Dubrovsky BO (2005). «Steroids, neuroactive steroids and neurosteroids in psychopathology». Prog. Neuropsychopharmacol. Biol. Psychiatry. 29 (2): 169–92. PMID15694225. doi:10.1016/j.pnpbp.2004.11.001; (h) Mellon SH, Griffin LD (2002). «Neurosteroids: biochemistry and clinical significance». Trends Endocrinol. Metab. 13 (1): 35–43. PMID11750861. doi:10.1016/S1043-2760(01)00503-3; (i) Puia G, Santi MR, Vicini S, Pritchett DB, Purdy RH, Paul SM, Seeburg PH, Costa E (1990). «Neurosteroids act on recombinant human GABAA receptors». Neuron. 4 (5): 759–65. PMID2160838 !CS1 manut: Nomes múltiplos: lista de autores (link); (j) Majewska MD, Harrison NL, Schwartz RD, Barker JL, Paul SM (1986). «Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor». Science. 232 (4753): 1004–7. PMID2422758. doi:10.1126/science.2422758 !CS1 manut: Nomes múltiplos: lista de autores (link)
Dawson GR, Maubach KA, Collinson N, Cobain M, Everitt BJ, MacLeod AM, Choudhury HI, McDonald LM, Pillai G, Rycroft W, Smith AJ, Sternfeld F, Tattersall FD, Wafford KA, Reynolds DS, Seabrook GR, Atack JR (2006). «An inverse agonist selective for alpha5 subunit-containing GABAA receptors enhances cognition». J. Pharmacol. Exp. Ther. 316 (3): 1335–45. PMID16326923. doi:10.1124/jpet.105.092320 !CS1 manut: Nomes múltiplos: lista de autores (link)
Sigel E (2002). «Mapping of the benzodiazepine recognition site on GABAA receptors». Curr Top Med Chem. 2 (8): 833–9. PMID12171574. doi:10.2174/1568026023393444
Akabas MH (2004). «GABAA receptor structure-function studies: a reexamination in light of new acetylcholine receptor structures». Int. Rev. Neurobiol. 62: 1–43. PMID15530567. doi:10.1016/S0074-7742(04)62001-0
Derry JM, Dunn SM, Davies M (2004). «Identification of a residue in the gamma-aminobutyric acid type A receptor alpha subunit that differentially affects diazepam-sensitive and -insensitive benzodiazepine site binding». J. Neurochem. 88 (6): 1431–8. PMID15009644. doi:10.1046/j.1471-4159.2003.02264.x !CS1 manut: Nomes múltiplos: lista de autores (link)
Atack JR. Anxioselective compounds acting at the GABA(A) receptor benzodiazepine binding site. Current Drug Targets. CNS and Neurological Disorders. 2003 Aug;2(4):213-32. PMID 12871032
Hanson SM, Czajkowski C (2008). «Structural mechanisms underlying benzodiazepine modulation of the GABA(A) receptor». J. Neurosci. 28 (13): 3490–9. PMID18367615. doi:10.1523/JNEUROSCI.5727-07.2008
Twyman RE, Rogers CJ, Macdonald RL (1989). «Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbital». Ann. Neurol. 25 (3): 213–20. PMID2471436. doi:10.1002/ana.410250302 !CS1 manut: Nomes múltiplos: lista de autores (link)