Safrol (Portuguese Wikipedia)

Analysis of information sources in references of the Wikipedia article "Safrol" in Portuguese language version.

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27doi.org

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18nih.gov

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11worldcat.org

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7hathitrust.org

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2books.google.com

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1federalregister.gov

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1europa.eu

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1irrawaddy.org

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1purdue.edu

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The history of research on safrole appears in: Semmler, F.W. (1907). Die Ätherischen Öle nach ihren chemischen Bestandteilen unter Berücksichtigung der geschichtlichen Entwicklung [The volatile oils according to their chemical components with regard to their historical development] (em alemão). 4. Leipzig, Germany: Veit & Co. pp. 139–144
Ledgard, Jared (2010). Kings Chem Guide 2nd ed. [S.l.]: UVKCHEM, Inc. p. 206. ISBN 9780578058658. Consultado em 6 de setembro de 2014

doi.org

dx.doi.org

Kamdem, Donatien; Gage, Douglas (2007). «Chemical Composition of Essential Oil from the Root Bark of Sassafras albidum». Planta Medica. 61 (6): 574–5. PMID 8824955. doi:10.1055/s-2006-959379
Hickey, Michael J. (1948). «Investigation of the chemical constituents of Brazilian sassafras oil». Journal of Organic Chemistry. 13 (3): 443–6. PMID 18863852. doi:10.1021/jo01161a020
Poleck, Theodor (1884). «Ueber die chemische Constitution des Safrols» [On the chemical composition of safrole]. Berichte der Deutschen Chemischen Gesellschaft. 17 (2): 1940–1944. doi:10.1002/cber.18840170278 See structural formula on p. 1941.
Eijkman, J.F. (1885). «Sur les principes constituants de l'Illicium religiosum (Sieb.) (Shikimi-no-ki en japonais)» [On the substances composing Illicium religiosum (Sieb.) (Shikimi-no-ki in Japanese)]. Recueil des Travaux Chimiques des Pays-Bas (em francês). 4 (2): 32–54. doi:10.1002/recl.18850040202 ; see pp. 39–40.
Fittig, Rud.; Remsen, Ira (1871). «Untersuchungen über die Constitution des Piperins und seiner Spaltungsproducte Piperinsäure und Piperidin» [Investigations into the composition of piperine and its cleavage products piperic acid and piperidine]. Annalen der Chemie (em alemão). 159 (2): 129–158. doi:10.1002/jlac.18711590202 ; Veja a fórmula estrutural do Ácido piperônico na p. 155.
Poleck, Th. (1886). «Ueber die chemische Structur des Safrols» [On the chemical structure of safrole]. Berichte der Deutschen Chemischen Gesellschaft (em alemão). 19: 1094–1098. doi:10.1002/cber.188601901243
Brühl, J.W. (1888). «Untersuchungen über die Terpene und deren Abkömmlinge» [Investigations of the terpenes and their derivatives]. Berichte der Deutschen Chemischen Gesellschaft (em alemão). 21: 457–477. doi:10.1002/cber.18880210181 ; see pp. 474–477.
Perkin, William Henry; Trikojus, Victor Martin (1927). «CCXII.—A synthesis of safrole and o-safrole». Journal of the Chemical Society: 1663–1666. doi:10.1039/JR9270001663
Kamdem, Donatien; Gage, Douglas (1 de dezembro de 1995). «Chemical Composition of Essential Oil from the Root Bark of Sassafras albidum». Planta Medica (em inglês). 61 (6): 574–575. ISSN 0032-0943. PMID 8824955. doi:10.1055/s-2006-959379
Hickey, M. J. (1 de maio de 1948). «Investigation of the chemical constituents of Brazilian sassafras oil». The Journal of Organic Chemistry. 13 (3): 443–446. ISSN 0022-3263. PMID 18863852. doi:10.1021/jo01161a020
Wisneski, Harris H.; Yates, Ronald L.; Davis, Henry M. (1983). «High-performance liquid chromatographic—fluorometric determination of safrole in perfume, cologne and toilet water». Journal of Chromatography A (em inglês). 255: 455–461. doi:10.1016/s0021-9673(01)88300-x
Hung, Shan-Ling; Chen, Yu-Ling; Chen, Yen-Ting (1 de abril de 2003). «Effects of safrole on the defensive functions of human neutrophils». Journal of Periodontal Research. 38 (2): 130–134. ISSN 0022-3484. PMID 12608906. doi:10.1034/j.1600-0765.2003.01652.x
Zhao, Jing; Miao, Junying; Zhao, Baoxiang; Zhang, Shangli; Yin, Deling (1 de junho de 2005). «Safrole oxide inhibits angiogenesis by inducing apoptosis». Vascular Pharmacology. 43 (1): 69–74. ISSN 1537-1891. PMID 15936989. doi:10.1016/j.vph.2005.04.004
Perkin, William Henry; Trikojus, Victor Martin (1 de janeiro de 1927). «CCXII.—A synthesis of safrole and o-safrole». J. Chem. Soc. (em inglês): 1663–1666. ISSN 0368-1769. doi:10.1039/jr9270001663
Lima, P. C.; Lima, L. M.; da Silva, K. C.; Léda, P. H.; de Miranda, A. L.; Fraga, C. A.; Barreiro, E. J. (1 de fevereiro de 2000). «Synthesis and analgesic activity of novel N-acylarylhydrazones and isosters, derived from natural safrole». European Journal of Medicinal Chemistry. 35 (2): 187–203. ISSN 0223-5234. PMID 10758281. doi:10.1016/s0223-5234(00)00120-3
Lages, A. S.; Silva, K. C.; Miranda, A. L.; Fraga, C. A.; Barreiro, E. J. (20 de janeiro de 1998). «Synthesis and pharmacological evaluation of new flosulide analogues, synthesized from natural safrole». Bioorganic & Medicinal Chemistry Letters. 8 (2): 183–188. ISSN 0960-894X. PMID 9871651. doi:10.1016/s0960-894x(97)10216-5
Lima, L.M.; Amarante, E.G.; Miranda, A.L.P.; Fraga, C.A.M.; Barreiro, E.J. (1999). «Synthesis and Antinociceptive Profile of Novel Acidic Sulphonylhydrazone Derivatives From Natural Safrole». Pharmacy and Pharmacology Communications. 5 (12): 673–678. doi:10.1211/146080899128734370
Fraga, Carlos A. M.; Barreiro, Eliezer J. (1 de outubro de 1992). «The synthesis of a new benzothiazine derivative, related to oxicams, synthesized from natural safrole». Journal of Heterocyclic Chemistry (em inglês). 29 (6): 1667–1669. ISSN 1943-5193. doi:10.1002/jhet.5570290652
Ioannides, C.; Delaforge, M.; Parke, D. V. (1 de outubro de 1981). «Safrole: its metabolism, carcinogenicity and interactions with cytochrome P-450». Food and Cosmetics Toxicology. 19 (5): 657–666. ISSN 0015-6264. PMID 7030889. doi:10.1016/0015-6264(81)90518-6
Sekizawa, J.; Shibamoto, T. (1 de abril de 1982). «Genotoxicity of safrole-related chemicals in microbial test systems». Mutation Research. 101 (2): 127–140. ISSN 0027-5107. PMID 6808388. doi:10.1016/0165-1218(82)90003-9
Jeurissen, Suzanne M. F.; Bogaards, Jan J. P.; Awad, Hanem M.; Boersma, Marelle G.; Brand, Walter; Fiamegos, Yiannis C.; van Beek, Teris A.; Alink, Gerrit M.; Sudhölter, Ernst J. R. (1 de setembro de 2004). «Human cytochrome p450 enzyme specificity for bioactivation of safrole to the proximate carcinogen 1'-hydroxysafrole». Chemical Research in Toxicology. 17 (9): 1245–1250. ISSN 0893-228X. PMID 15377158. doi:10.1021/tx040001v
MacFabe, Derrick F.; Cain, Donald P.; Rodriguez-Capote, Karina; Franklin, Andrew E.; Hoffman, Jennifer E.; Boon, Francis; Taylor, A. Roy; Kavaliers, Martin; Ossenkopp, Klaus-Peter (10 de janeiro de 2007). «Neurobiological effects of intraventricular propionic acid in rats: Possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum disorders». Behavioural Brain Research. Animal Models for Autism. 176 (1): 149–169. PMID 16950524. doi:10.1016/j.bbr.2006.07.025
Hagan, Ernest C.; Jenner, Paul M.; Jones, Wm.I.; Fitzhugh, O.Garth; Long, Eleanor L.; Brouwer, J.G.; Webb, Willis K. (1965). «Toxic properties of compounds related to safrole». Toxicology and Applied Pharmacology (em inglês). 7 (1): 18–24. PMID 14259070. doi:10.1016/0041-008x(65)90069-4
Liu, T.Y.; Chen, C.C.; Chen, C.L.; Chi, C.W. (1999). «Safrole-induced Oxidative Damage in the Liver of Sprague–Dawley Rats». Food and Chemical Toxicology. 37 (7): 697–702. PMID 10496370. doi:10.1016/S0278-6915(99)00055-1
Benedetti, M; Malnoe, A; Broillet, A (1977). «Absorption, metabolism and excretion of safrole in the rat and man». Toxicology. 7 (1): 69–83. PMID 14422. doi:10.1016/0300-483X(77)90039-7
Liu, T. Y.; Chen, C. C.; Chen, C. L.; Chi, C. W. (1 de julho de 1999). «Safrole-induced Oxidative Damage in the Liver of Sprague–Dawley Rats». Food and Chemical Toxicology. 37 (7): 697–702. PMID 10496370. doi:10.1016/S0278-6915(99)00055-1
Su, Le; Zhao, BaoXiang; Lv, Xin; Wang, Nan; Zhao, Jing; Zhang, ShangLi; Miao, JunYing (20 de fevereiro de 2007). «Safrole oxide induces neuronal apoptosis through inhibition of integrin β4/SOD activity and elevation of ROS/NADPH oxidase activity». Life Sciences. 80 (11): 999–1006. PMID 17188719. doi:10.1016/j.lfs.2006.11.041

erowid.org

«Synthesis of Safrole - [www.rhodium.ws]». erowid.org. Consultado em 27 de abril de 2017

europa.eu

ec.europa.eu

Opinion of the Scientific Committee on Food on the safety of the presence of safrole (1-allyl-3,4-methylenedioxybenzene) in flavourings and other food ingredients with flavouring properties

federalregister.gov

archives.federalregister.gov

Harvey, John L. (2 de dezembro de 1960). «Refusal to Extend Effective Date of Statute for Certain Specified Food Additives» (PDF). Federal Register Archive. United States Food & Drug Administration. p. 12412. Consultado em 28 de novembro de 2022

globalpost.com

Campbell, Sam (30 de agosto de 2009). «Harvested to make Ecstasy, Cambodia's trees are felled one by one.». GlobalPost. Consultado em 2 de setembro de 2009

hathitrust.org

babel.hathitrust.org

Saint-Èvre (1844). «Recherches sur l'huile essentielle de sassafras» [Investigations of the essential oil of sassafras]. Annales de Chimie et de Physique. 3rd series (em francês). 12: 107–113 ; see p. 108.
Grimaux, E; Ruotte, J. (1869). «Sur l'essence de sassafras» [On the essential oil of sassafras]. Comptes Rendus (em francês). 68: 928–930 From p. 928: "Ils sont constitués par une principe oxygéné, la safrol C₁₀H₁₀O₂ … " (They [the fractions of essential oil that are safrole] are composed of an oxygenated substance, safrole C₁₀H₁₀O₂ … )
Poleck, Theodor (1884). «Ueber die chemische Constitution des Safrols» [On the chemical composition of safrole]. Berichte der Deutschen Chemischen Gesellschaft. 17 (2): 1940–1944. doi:10.1002/cber.18840170278 See structural formula on p. 1941.
Eijkman, J.F. (1885). «Sur les principes constituants de l'Illicium religiosum (Sieb.) (Shikimi-no-ki en japonais)» [On the substances composing Illicium religiosum (Sieb.) (Shikimi-no-ki in Japanese)]. Recueil des Travaux Chimiques des Pays-Bas (em francês). 4 (2): 32–54. doi:10.1002/recl.18850040202 ; see pp. 39–40.
Fittig, Rud.; Remsen, Ira (1871). «Untersuchungen über die Constitution des Piperins und seiner Spaltungsproducte Piperinsäure und Piperidin» [Investigations into the composition of piperine and its cleavage products piperic acid and piperidine]. Annalen der Chemie (em alemão). 159 (2): 129–158. doi:10.1002/jlac.18711590202 ; Veja a fórmula estrutural do Ácido piperônico na p. 155.
Poleck, Th. (1886). «Ueber die chemische Structur des Safrols» [On the chemical structure of safrole]. Berichte der Deutschen Chemischen Gesellschaft (em alemão). 19: 1094–1098. doi:10.1002/cber.188601901243
Brühl, J.W. (1888). «Untersuchungen über die Terpene und deren Abkömmlinge» [Investigations of the terpenes and their derivatives]. Berichte der Deutschen Chemischen Gesellschaft (em alemão). 21: 457–477. doi:10.1002/cber.18880210181 ; see pp. 474–477.

incb.org

International Narcotics Control Board Arquivado em 2008-02-27 no Wayback Machine

irrawaddy.org

www2.irrawaddy.org

Blickman, Tom (3 de fevereiro de 2009). «Harvesting Trees to Make Ecstasy Drug». The Irrawaddy

nih.gov

ncbi.nlm.nih.gov

Kamdem, Donatien; Gage, Douglas (2007). «Chemical Composition of Essential Oil from the Root Bark of Sassafras albidum». Planta Medica. 61 (6): 574–5. PMID 8824955. doi:10.1055/s-2006-959379
Hickey, Michael J. (1948). «Investigation of the chemical constituents of Brazilian sassafras oil». Journal of Organic Chemistry. 13 (3): 443–6. PMID 18863852. doi:10.1021/jo01161a020
Kamdem, Donatien; Gage, Douglas (1 de dezembro de 1995). «Chemical Composition of Essential Oil from the Root Bark of Sassafras albidum». Planta Medica (em inglês). 61 (6): 574–575. ISSN 0032-0943. PMID 8824955. doi:10.1055/s-2006-959379
Hickey, M. J. (1 de maio de 1948). «Investigation of the chemical constituents of Brazilian sassafras oil». The Journal of Organic Chemistry. 13 (3): 443–446. ISSN 0022-3263. PMID 18863852. doi:10.1021/jo01161a020
Hung, Shan-Ling; Chen, Yu-Ling; Chen, Yen-Ting (1 de abril de 2003). «Effects of safrole on the defensive functions of human neutrophils». Journal of Periodontal Research. 38 (2): 130–134. ISSN 0022-3484. PMID 12608906. doi:10.1034/j.1600-0765.2003.01652.x
Zhao, Jing; Miao, Junying; Zhao, Baoxiang; Zhang, Shangli; Yin, Deling (1 de junho de 2005). «Safrole oxide inhibits angiogenesis by inducing apoptosis». Vascular Pharmacology. 43 (1): 69–74. ISSN 1537-1891. PMID 15936989. doi:10.1016/j.vph.2005.04.004
Lima, P. C.; Lima, L. M.; da Silva, K. C.; Léda, P. H.; de Miranda, A. L.; Fraga, C. A.; Barreiro, E. J. (1 de fevereiro de 2000). «Synthesis and analgesic activity of novel N-acylarylhydrazones and isosters, derived from natural safrole». European Journal of Medicinal Chemistry. 35 (2): 187–203. ISSN 0223-5234. PMID 10758281. doi:10.1016/s0223-5234(00)00120-3
Lages, A. S.; Silva, K. C.; Miranda, A. L.; Fraga, C. A.; Barreiro, E. J. (20 de janeiro de 1998). «Synthesis and pharmacological evaluation of new flosulide analogues, synthesized from natural safrole». Bioorganic & Medicinal Chemistry Letters. 8 (2): 183–188. ISSN 0960-894X. PMID 9871651. doi:10.1016/s0960-894x(97)10216-5
Ioannides, C.; Delaforge, M.; Parke, D. V. (1 de outubro de 1981). «Safrole: its metabolism, carcinogenicity and interactions with cytochrome P-450». Food and Cosmetics Toxicology. 19 (5): 657–666. ISSN 0015-6264. PMID 7030889. doi:10.1016/0015-6264(81)90518-6
Sekizawa, J.; Shibamoto, T. (1 de abril de 1982). «Genotoxicity of safrole-related chemicals in microbial test systems». Mutation Research. 101 (2): 127–140. ISSN 0027-5107. PMID 6808388. doi:10.1016/0165-1218(82)90003-9
Jeurissen, Suzanne M. F.; Bogaards, Jan J. P.; Awad, Hanem M.; Boersma, Marelle G.; Brand, Walter; Fiamegos, Yiannis C.; van Beek, Teris A.; Alink, Gerrit M.; Sudhölter, Ernst J. R. (1 de setembro de 2004). «Human cytochrome p450 enzyme specificity for bioactivation of safrole to the proximate carcinogen 1'-hydroxysafrole». Chemical Research in Toxicology. 17 (9): 1245–1250. ISSN 0893-228X. PMID 15377158. doi:10.1021/tx040001v
MacFabe, Derrick F.; Cain, Donald P.; Rodriguez-Capote, Karina; Franklin, Andrew E.; Hoffman, Jennifer E.; Boon, Francis; Taylor, A. Roy; Kavaliers, Martin; Ossenkopp, Klaus-Peter (10 de janeiro de 2007). «Neurobiological effects of intraventricular propionic acid in rats: Possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum disorders». Behavioural Brain Research. Animal Models for Autism. 176 (1): 149–169. PMID 16950524. doi:10.1016/j.bbr.2006.07.025
Hagan, Ernest C.; Jenner, Paul M.; Jones, Wm.I.; Fitzhugh, O.Garth; Long, Eleanor L.; Brouwer, J.G.; Webb, Willis K. (1965). «Toxic properties of compounds related to safrole». Toxicology and Applied Pharmacology (em inglês). 7 (1): 18–24. PMID 14259070. doi:10.1016/0041-008x(65)90069-4
Liu, T.Y.; Chen, C.C.; Chen, C.L.; Chi, C.W. (1999). «Safrole-induced Oxidative Damage in the Liver of Sprague–Dawley Rats». Food and Chemical Toxicology. 37 (7): 697–702. PMID 10496370. doi:10.1016/S0278-6915(99)00055-1
Benedetti, M; Malnoe, A; Broillet, A (1977). «Absorption, metabolism and excretion of safrole in the rat and man». Toxicology. 7 (1): 69–83. PMID 14422. doi:10.1016/0300-483X(77)90039-7
Liu, T. Y.; Chen, C. C.; Chen, C. L.; Chi, C. W. (1 de julho de 1999). «Safrole-induced Oxidative Damage in the Liver of Sprague–Dawley Rats». Food and Chemical Toxicology. 37 (7): 697–702. PMID 10496370. doi:10.1016/S0278-6915(99)00055-1
Su, Le; Zhao, BaoXiang; Lv, Xin; Wang, Nan; Zhao, Jing; Zhang, ShangLi; Miao, JunYing (20 de fevereiro de 2007). «Safrole oxide induces neuronal apoptosis through inhibition of integrin β4/SOD activity and elevation of ROS/NADPH oxidase activity». Life Sciences. 80 (11): 999–1006. PMID 17188719. doi:10.1016/j.lfs.2006.11.041

toxnet.nlm.nih.gov

«Ranking Possible Cancer Hazards on the HERP Index» (PDF). Consultado em 22 de outubro de 2013

purdue.edu

hort.purdue.edu

Rocha, Sérgio F.R.; Ming, Lin Chau (1999). «Piper hispidinervum: A Sustainable Source of Safrole». In: Janick, Jules. Perspectives on new crops and new uses. Alexandria, Virginia: ASHS Press. pp. 479–81. ISBN 978-0-9615027-0-6

web.archive.org

International Narcotics Control Board Arquivado em 2008-02-27 no Wayback Machine

worldcat.org

Kamdem, Donatien; Gage, Douglas (1 de dezembro de 1995). «Chemical Composition of Essential Oil from the Root Bark of Sassafras albidum». Planta Medica (em inglês). 61 (6): 574–575. ISSN 0032-0943. PMID 8824955. doi:10.1055/s-2006-959379
Hickey, M. J. (1 de maio de 1948). «Investigation of the chemical constituents of Brazilian sassafras oil». The Journal of Organic Chemistry. 13 (3): 443–446. ISSN 0022-3263. PMID 18863852. doi:10.1021/jo01161a020
Hung, Shan-Ling; Chen, Yu-Ling; Chen, Yen-Ting (1 de abril de 2003). «Effects of safrole on the defensive functions of human neutrophils». Journal of Periodontal Research. 38 (2): 130–134. ISSN 0022-3484. PMID 12608906. doi:10.1034/j.1600-0765.2003.01652.x
Zhao, Jing; Miao, Junying; Zhao, Baoxiang; Zhang, Shangli; Yin, Deling (1 de junho de 2005). «Safrole oxide inhibits angiogenesis by inducing apoptosis». Vascular Pharmacology. 43 (1): 69–74. ISSN 1537-1891. PMID 15936989. doi:10.1016/j.vph.2005.04.004
Perkin, William Henry; Trikojus, Victor Martin (1 de janeiro de 1927). «CCXII.—A synthesis of safrole and o-safrole». J. Chem. Soc. (em inglês): 1663–1666. ISSN 0368-1769. doi:10.1039/jr9270001663
Lima, P. C.; Lima, L. M.; da Silva, K. C.; Léda, P. H.; de Miranda, A. L.; Fraga, C. A.; Barreiro, E. J. (1 de fevereiro de 2000). «Synthesis and analgesic activity of novel N-acylarylhydrazones and isosters, derived from natural safrole». European Journal of Medicinal Chemistry. 35 (2): 187–203. ISSN 0223-5234. PMID 10758281. doi:10.1016/s0223-5234(00)00120-3
Lages, A. S.; Silva, K. C.; Miranda, A. L.; Fraga, C. A.; Barreiro, E. J. (20 de janeiro de 1998). «Synthesis and pharmacological evaluation of new flosulide analogues, synthesized from natural safrole». Bioorganic & Medicinal Chemistry Letters. 8 (2): 183–188. ISSN 0960-894X. PMID 9871651. doi:10.1016/s0960-894x(97)10216-5
Fraga, Carlos A. M.; Barreiro, Eliezer J. (1 de outubro de 1992). «The synthesis of a new benzothiazine derivative, related to oxicams, synthesized from natural safrole». Journal of Heterocyclic Chemistry (em inglês). 29 (6): 1667–1669. ISSN 1943-5193. doi:10.1002/jhet.5570290652
Ioannides, C.; Delaforge, M.; Parke, D. V. (1 de outubro de 1981). «Safrole: its metabolism, carcinogenicity and interactions with cytochrome P-450». Food and Cosmetics Toxicology. 19 (5): 657–666. ISSN 0015-6264. PMID 7030889. doi:10.1016/0015-6264(81)90518-6
Sekizawa, J.; Shibamoto, T. (1 de abril de 1982). «Genotoxicity of safrole-related chemicals in microbial test systems». Mutation Research. 101 (2): 127–140. ISSN 0027-5107. PMID 6808388. doi:10.1016/0165-1218(82)90003-9
Jeurissen, Suzanne M. F.; Bogaards, Jan J. P.; Awad, Hanem M.; Boersma, Marelle G.; Brand, Walter; Fiamegos, Yiannis C.; van Beek, Teris A.; Alink, Gerrit M.; Sudhölter, Ernst J. R. (1 de setembro de 2004). «Human cytochrome p450 enzyme specificity for bioactivation of safrole to the proximate carcinogen 1'-hydroxysafrole». Chemical Research in Toxicology. 17 (9): 1245–1250. ISSN 0893-228X. PMID 15377158. doi:10.1021/tx040001v