Cook E.H., Fletcher K.E., Wainwright M., Marks N., Yan S.Y., Leventhal B.L. Primary structure of the human platelet serotonin 5-HT2 receptor: identity with frontal cortex serotonin 5-HT2A receptor (англ.) // J. Neurochem.[англ.] : journal. — 1994. — August (vol. 63, no. 2). — P. 465—469. — doi:10.1046/j.1471-4159.1994.63020465.x. — PMID8035173.
Martin P., Waters N., Schmidt C.J., Carlsson A., Carlsson M.L. Rodent data and general hypothesis: antipsychotic action exerted through 5-HT2A receptor antagonism is dependent on increased serotonergic tone (англ.) // J Neural Transm[англ.] : journal. — 1998. — Vol. 105, no. 4—5. — P. 365—396. — doi:10.1007/s007020050064. — PMID9720968.
Elphick G.F., Querbes W., Jordan J.A., Gee G.V., Eash S., Manley K., Dugan A., Stanifer M., Bhatnagar A., Kroeze W.K., Roth B.L., Atwood W.J. The human polyomavirus, JCV, uses serotonin receptors to infect cells (англ.) // Science : journal. — 2004. — Vol. 306, no. 5700. — P. 1380—1383. — doi:10.1126/science.1103492. — PMID15550673.
Aghajanian G.K., Marek G.J. Serotonin, via 5-HT2A receptors, increases EPSCs in layer V pyramidal cells of prefrontal cortex by an asynchronous mode of glutamate release (англ.) // Brain Res.[англ.] : journal. — 1999. — April (vol. 825, no. 1—2). — P. 161—171. — doi:10.1016/S0006-8993(99)01224-X. — PMID10216183.
Marek G.J., Wright R.A., Gewirtz J.C., Schoepp D.D. A major role for thalamocortical afferents in serotonergic hallucinogen receptor function in the rat neocortex (англ.) // Neuroscience[англ.] : journal. — Elsevier, 2001. — Vol. 105, no. 2. — P. 379—392. — doi:10.1016/S0306-4522(01)00199-3. — PMID11672605.
Bortolozzi A., Díaz-Mataix L., Scorza M.C., Celada P., Artigas F. The activation of 5-HT receptors in prefrontal cortex enhances dopaminergic activity (англ.) // J. Neurochem.[англ.] : journal. — 2005. — December (vol. 95, no. 6). — P. 1597—1607. — doi:10.1111/j.1471-4159.2005.03485.x. — PMID16277612.
Amargós-Bosch M., Bortolozzi A., Puig M.V., Serrats J., Adell A., Celada P., Toth M., Mengod G., Artigas F. Co-expression and in vivo interaction of serotonin1A and serotonin2A receptors in pyramidal neurons of prefrontal cortex (англ.) // Cereb. Cortex[англ.] : journal. — 2004. — March (vol. 14, no. 3). — P. 281—299. — doi:10.1093/cercor/bhg128. — PMID14754868.
Marek G.J. Activation of adenosine(1) (A(1)) receptors suppresses head shakes induced by a serotonergic hallucinogen in rats (англ.) // Neuropharmacology : journal. — 2009. — March (vol. 56, no. 8). — P. 1082—1087. — doi:10.1016/j.neuropharm.2009.03.005. — PMID19324062. — PMC2706691.
Marek G.J., Zhang C. Activation of metabotropic glutamate 5 (mGlu5) receptors induces spontaneous excitatory synaptic currents in layer V pyramidal cells of the rat prefrontal cortex (англ.) // Neurosci. Lett.[англ.] : journal. — 2008. — September (vol. 442, no. 3). — P. 239—243. — doi:10.1016/j.neulet.2008.06.083. — PMID18621097. — PMC2677702.
Geurts F.J., De Schutter E., Timmermans J.P. Localization of 5-HT2A, 5-HT3, 5-HT5A and 5-HT7 receptor-like immunoreactivity in the rat cerebellum (англ.) // Journal of chemical neuroanatomy : journal. — 2002. — June (vol. 24, no. 1). — P. 65—74. — doi:10.1016/S0891-0618(02)00020-0. — PMID12084412.
Maeshima T., Shutoh F., Hamada S., Senzaki K., Hamaguchi-Hamada K., Ito R., Okado N. Serotonin2A receptor-like immunoreactivity in rat cerebellar Purkinje cells (англ.) // Neurosci. Lett.[англ.] : journal. — 1998. — August (vol. 252, no. 1). — P. 72—74. — doi:10.1016/S0304-3940(98)00546-1. — PMID9756362.
Maeshima T., Shiga T., Ito R., Okado N. Expression of serotonin2A receptors in Purkinje cells of the developing rat cerebellum (англ.) // Neurosci. Res. : journal. — 2004. — December (vol. 50, no. 4). — P. 411—417. — doi:10.1016/j.neures.2004.08.010. — PMID15567478.
Dürk T., Panther E., Müller T., Sorichter S., Ferrari D., Pizzirani C., Di Virgilio F., Myrtek D., Norgauer J., Idzko M. 5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes (англ.) // Int Immunol[англ.] : journal. — 2005. — May (vol. 17, no. 5). — P. 599—606. — doi:10.1093/intimm/dxh242. — PMID15802305.
Urban J.D., Clarke W.P., von Zastrow M., Nichols D.E., Kobilka B., Weinstein H., Javitch J.A., Roth B.L., Christopoulos A., Sexton P.M., Miller K.J., Spedding M., Mailman R.B. Functional selectivity and classical concepts of quantitative pharmacology (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2007. — Vol. 320, no. 1. — P. 1—13. — doi:10.1124/jpet.106.104463. — PMID16803859.
Yu B., Becnel J., Zerfaoui M., Rohatgi R., Boulares A. H., Nichols C. D. Serotonin 5-hydroxytryptamine(2A) receptor activation suppresses tumor necrosis factor-_-induced inflammation with extraordinary potency (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2008. — November (vol. 327, no. 2). — P. 316—323. — doi:10.1124/jpet.108.143461. — PMID18708586.
Nau F., Yu B., Martin D., Nichols C. D. Serotonin 5-HT2A Receptor Activation Blocks TNF-a Mediated Inflammation In Vivo (англ.) // PLOS One : journal. — 2013. — Vol. 8, no. 10. — P. e75426. — doi:10.1371/journal.pone.0075426. — PMID24098382.
Bortolozzi A., Díaz-Mataix L., Scorza M. C., Celada P., Artigas F. The activation of 5-HT receptors in prefrontal cortex enhances dopaminergic activity (англ.) // J. Neurochem.[англ.] : journal. — 2005. — Vol. 95, no. 6. — P. 1597—1607. — doi:10.1111/j.1471-4159.2005.03485.x. — PMID16277612.
Blaazer A.R., Smid P., Kruse C.G. Structure-activity relationships of phenylalkylamines as agonist ligands for 5-HT(2A) receptors (англ.) // ChemMedChem[англ.] : journal. — 2008. — Vol. 3, no. 9. — P. 1299—1309. — doi:10.1002/cmdc.200800133. — PMID18666267.
Moreno J.L., Muguruza C., Umali A., Mortillo S., Holloway T., Pilar-Cuéllar F., Mocci G., Seto J., Callado L.F., Neve R.L., Milligan G., Sealfon S.C., López-Giménez J.F., Meana J.J., Benson D.L., González-Maeso J. Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT2A{middle dot}mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function (англ.) // Journal of Biological Chemistry : journal. — 2012. — Vol. 287, no. 53. — P. 44301—44319. — doi:10.1074/jbc.M112.413161. — PMID23129762. — PMC3531745.
González-Maeso J., Ang R.L., Yuen T., Chan P., Weisstaub N.V., López-Giménez J.F., Zhou M., Okawa Y., Callado L.F., Milligan G., Gingrich J.A., Filizola M., Meana J.J., Sealfon S.C. Identification of a serotonin/glutamate receptor complex implicated in psychosis (англ.) // Nature : journal. — 2008. — Vol. 452, no. 7183. — P. 93—97. — doi:10.1038/nature06612. — PMID18297054. — PMC2743172.
Moreno J.L., Holloway T., Albizu L., Sealfon S.C., González-Maeso J. Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists (англ.) // Neuroscience Letters[англ.] : journal. — 2011. — Vol. 493, no. 3. — P. 76—79. — doi:10.1016/j.neulet.2011.01.046. — PMID21276828. — PMC3064746.
Wingen M., Kuypers K.P., Ramaekers J.G. The role of 5-HT1a and 5-HT2a receptors in attention and motor control: a mechanistic study in healthy volunteers (англ.) // Psychopharmacology[англ.] : journal. — Springer, 2007. — Vol. 190, no. 3. — P. 391—400. — doi:10.1007/s00213-006-0614-x. — PMID17124621.
Wingen M., Kuypers K.P., Ramaekers J.G. Selective verbal and spatial memory impairment after 5-HT1A and 5-HT2A receptor blockade in healthy volunteers pre-treated with an SSRI (англ.) // J. Psychopharmacol. (Oxford)[англ.] : journal. — 2007. — Vol. 21, no. 5. — P. 477—485. — doi:10.1177/0269881106072506. — PMID17092965.
Gatch M.B., Kozlenkov A., Huang R.Q., Yang W., Nguyen J.D., González-Maeso J., Rice K.C., France C.P., Dillon G.H., Forster M.J., Schetz J.A. The HIV Antiretroviral Drug Efavirenz has LSD-Like Properties (англ.) // Neuropsychopharmacology[англ.] : journal. — Nature Publishing Group, 2013. — Vol. 38, no. 12. — P. 2373—2384. — doi:10.1038/npp.2013.135. — PMID23702798.
Janowsky A., Eshleman A.J., Johnson R.A., Wolfrum K.M., Hinrichs D.J., Yang J., Zabriskie T.M., Smilkstein M.J., Riscoe M.K. Mefloquine and psychotomimetics share neurotransmitter receptor and transporter interactions in vitro (англ.) // Psychopharmacology[англ.] : journal. — Springer, 2014. — Vol. 231, no. 14. — P. 2771—2783. — doi:10.1007/s00213-014-3446-0. — PMID24488404.
Egan C.T., Herrick-Davis K., Miller K., Glennon R.A., Teitler M. Agonist activity of LSD and lisuride at cloned 5HT2A and 5HT2C receptors (англ.) // Psychopharmacology[англ.] : journal. — Springer, 1998. — April (vol. 136, no. 4). — P. 409—414. — doi:10.1007/s002130050585. — PMID9600588.
Sharif N.A., McLaughlin M.A., Kelly C.R. AL-34662: a potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist (англ.) // Journal of Ocular Pharmacology and Therapeutics : journal. — 2007. — February (vol. 23, no. 1). — P. 1—13. — doi:10.1089/jop.2006.0093. — PMID17341144.
May J.A., Dantanarayana A.P., Zinke P.W., McLaughlin M.A., Sharif N.A. 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity (англ.) // Journal of Medicinal Chemistry[англ.] : journal. — 2006. — January (vol. 49, no. 1). — P. 318—328. — doi:10.1021/jm050663x. — PMID16392816.
Shireman B.T., Dvorak C.A., Rudolph D.A., Bonaventure P., Nepomuceno D., Dvorak L., Miller K.L., Lovenberg T.W., Carruthers N.I. 2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists (англ.) // Bioorganic & Medicinal Chemistry Letters[англ.] : journal. — 2008. — March (vol. 18, no. 6). — P. 2103—2108. — doi:10.1016/j.bmcl.2008.01.090. — PMID18282705.
Westkaemper R.B., Runyon S.P., Bondarev M.L., Savage J.E., Roth B.L., Glennon R.A. 9-(Aminomethyl)-9,10-dihydroanthracene is a novel and unlikely 5-HT2A receptor antagonist (англ.) // Eur. J. Pharmacol.[англ.] : journal. — 1999. — September (vol. 380, no. 1). — P. R5—7. — doi:10.1016/S0014-2999(99)00525-7. — PMID10513561.
Westkaemper R.B., Glennon R.A. Application of ligand SAR, receptor modeling and receptor mutagenesis to the discovery and development of a new class of 5-HT2A ligands (англ.) // Curr Top Med Chem[англ.] : journal. — 2002. — June (vol. 2, no. 6). — P. 575—598. — doi:10.2174/1568026023393741. — PMID12052195.
Runyon S.P., Mosier P.D., Roth B.L., Glennon R.A., Westkaemper R.B. Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation (англ.) // J. Med. Chem.[англ.] : journal. — 2008. — November (vol. 51, no. 21). — P. 6808—6828. — doi:10.1021/jm800771x. — PMID18847250. — PMC3088499.
Wilson K.J., van Niel M.B., Cooper L., Bloomfield D., O'Connor D., Fish L.R., MacLeod A.M. 2,5-Disubstituted pyridines: the discovery of a novel series of 5-HT2A ligands (англ.) // Bioorg. Med. Chem. Lett.[англ.] : journal. — 2007. — May (vol. 17, no. 9). — P. 2643—2648. — doi:10.1016/j.bmcl.2007.01.098. — PMID17314044.
Vanover K.E., Harvey S.C., Son T., Bradley S.R., Kold H., Makhay M., Veinbergs I., Spalding T.A., Weiner D.M., Andersson C.M., Tolf B.R., Brann M.R., Hacksell U., Davis R.E. Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2004. — September (vol. 310, no. 3). — P. 943—951. — doi:10.1124/jpet.104.066688. — PMID15102927.
Vanover K.E., Weiner D.M., Makhay M., Veinbergs I., Gardell L.R., Lameh J., Del Tredici A.L., Piu F., Schiffer H.H., Ott T.R., Burstein E.S., Uldam A.K., Thygesen M.B., Schlienger N., Andersson C.M., Son T.Y., Harvey S.C., Powell S.B., Geyer M.A., Tolf B.R., Brann M.R., Davis R.E. Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2006. — May (vol. 317, no. 2). — P. 910—918. — doi:10.1124/jpet.105.097006. — PMID16469866.
Gardell L.R., Vanover K.E., Pounds L., Johnson R.W., Barido R., Anderson G.T., Veinbergs I., Dyssegaard A., Brunmark P., Tabatabaei A., Davis R.E., Brann M.R., Hacksell U., Bonhaus D.W. ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2007. — August (vol. 322, no. 2). — P. 862—870. — doi:10.1124/jpet.107.121715. — PMID17519387.
Vanover K.E., Betz A.J., Weber S.M., Bibbiani F., Kielaite A., Weiner D.M., Davis R.E., Chase T.N., Salamone J.D. A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model (англ.) // Pharmacol. Biochem. Behav.[англ.] : journal. — 2008. — October (vol. 90, no. 4). — P. 540—544. — doi:10.1016/j.pbb.2008.04.010. — PMID18534670. — PMC2806670.
Abbas A., Roth B.L. Pimavanserin tartrate: a 5-HT2A inverse agonist with potential for treating various neuropsychiatric disorders (англ.) // Expert Opin Pharmacother[англ.] : journal. — 2008. — December (vol. 9, no. 18). — P. 3251—3259. — doi:10.1517/14656560802532707. — PMID19040345.
Moya P.R., Berg K.A., Gutiérrez-Hernandez M.A., Sáez-Briones P., Reyes-Parada M., Cassels B.K., Clarke W.P. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine 5-HT2A and 5-HT2C receptors (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2007. — Vol. 321, no. 3. — P. 1054—1061. — doi:10.1124/jpet.106.117507. — PMID17337633.
González-Maeso J., Weisstaub N.V., Zhou M., Chan P., Ivic L., Ang R., Lira A., Bradley-Moore M., Ge Y., Zhou Q., Sealfon S.C., Gingrich J.A. Hallucinogens recruit specific cortical 5-HT2A receptor-mediated signaling pathways to affect behavior (англ.) // Neuron : journal. — Cell Press, 2007. — Vol. 53, no. 3. — P. 439—452. — doi:10.1016/j.neuron.2007.01.008. — PMID17270739.
Cussac D., Boutet-Robinet E., Ailhaud M.C., Newman-Tancredi A., Martel J.C., Danty N., Rauly-Lestienne I. Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells (англ.) // Eur. J. Pharmacol.[англ.] : journal. — 2008. — October (vol. 594, no. 1—3). — P. 32—8. — doi:10.1016/j.ejphar.2008.07.040. — PMID18703043.
Choi M.J., Lee H.J., Lee H.J., Ham B.J., Cha J.H., Ryu S.H., Lee M.S. Association between major depressive disorder and the -1438A/G polymorphism of the serotonin 2A receptor gene (англ.) // Neuropsychobiology[англ.] : journal. — 2004. — Vol. 49, no. 1. — P. 38—41. — doi:10.1159/000075337. — PMID14730199.
Williams J., Spurlock G., McGuffin P., Mallet J., Nöthen M.M., Gill M., Aschauer H., Nylander P.O., Macciardi F., Owen M.J. Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. European Multicentre Association Study of Schizophrenia (EMASS) Group (англ.) // The Lancet : journal. — Elsevier, 1996. — Vol. 347, no. 9011. — P. 1294—1296. — doi:10.1016/s0140-6736(96)90939-3. — PMID8622505.
Vaquero-Lorenzo C., Baca-Garcia E., Diaz-Hernandez M., Perez-Rodriguez M.M., Fernandez-Navarro P., Giner L., Carballo J.J., Saiz-Ruiz J., Fernandez-Piqueras J., Baldomero E.B., de Leon J., Oquendo M.A. Association study of two polymorphisms of the serotonin-2A receptor gene and suicide attempts (англ.) // American Journal of Medical Genetics[англ.] : journal. — 2008. — July (vol. 147B, no. 5). — P. 645—649. — doi:10.1002/ajmg.b.30642. — PMID18163387.
Serretti A., Drago A., De Ronchi D. HTR2A gene variants and psychiatric disorders: a review of current literature and selection of SNPs for future studies (англ.) // Current medicinal chemistry[англ.] : journal. — 2007. — Vol. 14, no. 19. — P. 2053—2069. — doi:10.2174/092986707781368450. — PMID17691947.
McMahon F.J., Buervenich S., Charney D., Lipsky R., Rush A.J., Wilson A.F., Sorant A.J., Papanicolaou G.J., Laje G., Fava M., Trivedi M.H., Wisniewski S.R., Manji H. Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment (англ.) // Am. J. Hum. Genet.[англ.] : journal. — 2006. — Vol. 78, no. 5. — P. 804—814. — doi:10.1086/503820. — PMID16642436. — PMC1474035.
Smith A.K., Dimulescu I., Falkenberg V.R., Narasimhan S., Heim C., Vernon S.D., Rajeevan M.S. Genetic evaluation of the serotonergic system in chronic fatigue syndrome (англ.) // Psychoneuroendocrinology : journal. — 2008. — Vol. 33, no. 2. — P. 188—197. — doi:10.1016/j.psyneuen.2007.11.001. — PMID18079067.
Lundkvist C., Halldin C., Ginovart N., Nyberg S., Swahn C.G., Carr A.A., Brunner F., Farde L.11C-MDL 100907, a radioligland for selective imaging of 5-HT2A receptors with positron emission tomography (англ.) // Life Sci.[англ.] : journal. — 1996. — Vol. 58, no. 10. — P. PL 187—192. — doi:10.1016/0024-3205(96)00013-6. — PMID8602111.
Mintun M.A., Sheline Y.I., Moerlein S.M., Vlassenko A.G., Huang Y., Snyder A.Z. Decreased hippocampal 5-HT2A receptor binding in major depressive disorder: in vivo measurement with [18F]-altanserin positron emission tomography (англ.) // Biological Psychiatry[англ.] : journal. — 2004. — Vol. 55, no. 3. — P. 217—224. — doi:10.1016/j.biopsych.2003.08.015. — PMID14744461.
Haugbøl S., Pinborg L.H., Regeur L., Hansen E.S., Bolwig T.G., Nielsen F.A., Svarer C., Skovgaard L.T., Knudsen G.M. Cerebral 5-HT2A receptor binding is increased in patients with Tourette's syndrome (англ.) // Int. J. Neuropsychopharmacol.[англ.] : journal. — 2007. — Vol. 10, no. 2. — P. 245—252. — doi:10.1017/S1461145706006559. — PMID16945163.
Rosier A., Dupont P., Peuskens J., Bormans G., Vandenberghe R., Maes M., de Groot T., Schiepers C., Verbruggen A., Mortelmans L. Visualisation of loss of 5-HT2A receptors with age in healthy volunteers using [18F]-altanserin and positron emission tomographic imaging (англ.) // Psychiatry Res.[англ.] : journal. — 1996. — Vol. 68, no. 1. — P. 11—22. — doi:10.1016/S0925-4927(96)02806-5. — PMID9027929.
Meltzer C.C., Smith G., Price J.C., Reynolds C.F., Mathis C.A., Greer P., Lopresti B., Mintun M.A., Pollock B.G., Ben-Eliezer D., Cantwell M.N., Kaye W., DeKosky S.T. Reduced binding of [18F]-altanserin to serotonin type 2A receptors in aging: persistence of effect after partial volume correction (англ.) // Brain Res.[англ.] : journal. — 1998. — Vol. 813, no. 1. — P. 167—171. — doi:10.1016/S0006-8993(98)00909-3. — PMID9824691.
Adams K.H., Pinborg L.H., Svarer C., Hasselbalch S.G., Holm S., Haugbøl S., Madsen K., Frøkjaer V., Martiny L., Paulson O.B., Knudsen G.M. A database of [18F]-altanserin binding to 5-HT2A receptors in normal volunteers: normative data and relationship to physiological and demographic variables (англ.) // NeuroImage[англ.] : journal. — 2004. — Vol. 21, no. 3. — P. 1105—1113. — doi:10.1016/j.neuroimage.2003.10.046. — PMID15006678.
Cook E.H., Fletcher K.E., Wainwright M., Marks N., Yan S.Y., Leventhal B.L. Primary structure of the human platelet serotonin 5-HT2 receptor: identity with frontal cortex serotonin 5-HT2A receptor (англ.) // J. Neurochem.[англ.] : journal. — 1994. — August (vol. 63, no. 2). — P. 465—469. — doi:10.1046/j.1471-4159.1994.63020465.x. — PMID8035173.
Martin P., Waters N., Schmidt C.J., Carlsson A., Carlsson M.L. Rodent data and general hypothesis: antipsychotic action exerted through 5-HT2A receptor antagonism is dependent on increased serotonergic tone (англ.) // J Neural Transm[англ.] : journal. — 1998. — Vol. 105, no. 4—5. — P. 365—396. — doi:10.1007/s007020050064. — PMID9720968.
Elphick G.F., Querbes W., Jordan J.A., Gee G.V., Eash S., Manley K., Dugan A., Stanifer M., Bhatnagar A., Kroeze W.K., Roth B.L., Atwood W.J. The human polyomavirus, JCV, uses serotonin receptors to infect cells (англ.) // Science : journal. — 2004. — Vol. 306, no. 5700. — P. 1380—1383. — doi:10.1126/science.1103492. — PMID15550673.
Aghajanian G.K., Marek G.J. Serotonin, via 5-HT2A receptors, increases EPSCs in layer V pyramidal cells of prefrontal cortex by an asynchronous mode of glutamate release (англ.) // Brain Res.[англ.] : journal. — 1999. — April (vol. 825, no. 1—2). — P. 161—171. — doi:10.1016/S0006-8993(99)01224-X. — PMID10216183.
Marek G.J., Wright R.A., Gewirtz J.C., Schoepp D.D. A major role for thalamocortical afferents in serotonergic hallucinogen receptor function in the rat neocortex (англ.) // Neuroscience[англ.] : journal. — Elsevier, 2001. — Vol. 105, no. 2. — P. 379—392. — doi:10.1016/S0306-4522(01)00199-3. — PMID11672605.
Bortolozzi A., Díaz-Mataix L., Scorza M.C., Celada P., Artigas F. The activation of 5-HT receptors in prefrontal cortex enhances dopaminergic activity (англ.) // J. Neurochem.[англ.] : journal. — 2005. — December (vol. 95, no. 6). — P. 1597—1607. — doi:10.1111/j.1471-4159.2005.03485.x. — PMID16277612.
Amargós-Bosch M., Bortolozzi A., Puig M.V., Serrats J., Adell A., Celada P., Toth M., Mengod G., Artigas F. Co-expression and in vivo interaction of serotonin1A and serotonin2A receptors in pyramidal neurons of prefrontal cortex (англ.) // Cereb. Cortex[англ.] : journal. — 2004. — March (vol. 14, no. 3). — P. 281—299. — doi:10.1093/cercor/bhg128. — PMID14754868.
Marek G.J. Activation of adenosine(1) (A(1)) receptors suppresses head shakes induced by a serotonergic hallucinogen in rats (англ.) // Neuropharmacology : journal. — 2009. — March (vol. 56, no. 8). — P. 1082—1087. — doi:10.1016/j.neuropharm.2009.03.005. — PMID19324062. — PMC2706691.
Marek G.J., Zhang C. Activation of metabotropic glutamate 5 (mGlu5) receptors induces spontaneous excitatory synaptic currents in layer V pyramidal cells of the rat prefrontal cortex (англ.) // Neurosci. Lett.[англ.] : journal. — 2008. — September (vol. 442, no. 3). — P. 239—243. — doi:10.1016/j.neulet.2008.06.083. — PMID18621097. — PMC2677702.
Geurts F.J., De Schutter E., Timmermans J.P. Localization of 5-HT2A, 5-HT3, 5-HT5A and 5-HT7 receptor-like immunoreactivity in the rat cerebellum (англ.) // Journal of chemical neuroanatomy : journal. — 2002. — June (vol. 24, no. 1). — P. 65—74. — doi:10.1016/S0891-0618(02)00020-0. — PMID12084412.
Maeshima T., Shutoh F., Hamada S., Senzaki K., Hamaguchi-Hamada K., Ito R., Okado N. Serotonin2A receptor-like immunoreactivity in rat cerebellar Purkinje cells (англ.) // Neurosci. Lett.[англ.] : journal. — 1998. — August (vol. 252, no. 1). — P. 72—74. — doi:10.1016/S0304-3940(98)00546-1. — PMID9756362.
Maeshima T., Shiga T., Ito R., Okado N. Expression of serotonin2A receptors in Purkinje cells of the developing rat cerebellum (англ.) // Neurosci. Res. : journal. — 2004. — December (vol. 50, no. 4). — P. 411—417. — doi:10.1016/j.neures.2004.08.010. — PMID15567478.
Dürk T., Panther E., Müller T., Sorichter S., Ferrari D., Pizzirani C., Di Virgilio F., Myrtek D., Norgauer J., Idzko M. 5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes (англ.) // Int Immunol[англ.] : journal. — 2005. — May (vol. 17, no. 5). — P. 599—606. — doi:10.1093/intimm/dxh242. — PMID15802305.
Urban J.D., Clarke W.P., von Zastrow M., Nichols D.E., Kobilka B., Weinstein H., Javitch J.A., Roth B.L., Christopoulos A., Sexton P.M., Miller K.J., Spedding M., Mailman R.B. Functional selectivity and classical concepts of quantitative pharmacology (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2007. — Vol. 320, no. 1. — P. 1—13. — doi:10.1124/jpet.106.104463. — PMID16803859.
Yu B., Becnel J., Zerfaoui M., Rohatgi R., Boulares A. H., Nichols C. D. Serotonin 5-hydroxytryptamine(2A) receptor activation suppresses tumor necrosis factor-_-induced inflammation with extraordinary potency (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2008. — November (vol. 327, no. 2). — P. 316—323. — doi:10.1124/jpet.108.143461. — PMID18708586.
Nau F., Yu B., Martin D., Nichols C. D. Serotonin 5-HT2A Receptor Activation Blocks TNF-a Mediated Inflammation In Vivo (англ.) // PLOS One : journal. — 2013. — Vol. 8, no. 10. — P. e75426. — doi:10.1371/journal.pone.0075426. — PMID24098382.
Zhang Y., Damjanoska K. J., Carrasco G. A., Dudas B., D'Souza D. N., Tetzlaff J., Garcia F., Hanley N. R., Scripathirathan K., Petersen B. R., Gray T. S., Battaglia G., Muma N. A., Van de Kar L. D. Evidence that 5-HT2A receptors in the hypothalamic paraventricular nucleus mediate neuroendocrine responses to (-)DOI (англ.) // J Neurosci.[англ.] : journal. — 2002. — November (vol. 22, no. 21). — P. 9635—9642. — PMID12417689.
Bortolozzi A., Díaz-Mataix L., Scorza M. C., Celada P., Artigas F. The activation of 5-HT receptors in prefrontal cortex enhances dopaminergic activity (англ.) // J. Neurochem.[англ.] : journal. — 2005. — Vol. 95, no. 6. — P. 1597—1607. — doi:10.1111/j.1471-4159.2005.03485.x. — PMID16277612.
Williams G. V., Rao S. G., Goldman-Rakic P. S. The physiological role of 5-HT2A receptors in working memory (англ.) // J. Neurosci.[англ.] : journal. — 2002. — Vol. 22, no. 7. — P. 2843—2854. — PMID11923449.
Blaazer A.R., Smid P., Kruse C.G. Structure-activity relationships of phenylalkylamines as agonist ligands for 5-HT(2A) receptors (англ.) // ChemMedChem[англ.] : journal. — 2008. — Vol. 3, no. 9. — P. 1299—1309. — doi:10.1002/cmdc.200800133. — PMID18666267.
Moreno J.L., Muguruza C., Umali A., Mortillo S., Holloway T., Pilar-Cuéllar F., Mocci G., Seto J., Callado L.F., Neve R.L., Milligan G., Sealfon S.C., López-Giménez J.F., Meana J.J., Benson D.L., González-Maeso J. Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT2A{middle dot}mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function (англ.) // Journal of Biological Chemistry : journal. — 2012. — Vol. 287, no. 53. — P. 44301—44319. — doi:10.1074/jbc.M112.413161. — PMID23129762. — PMC3531745.
González-Maeso J., Ang R.L., Yuen T., Chan P., Weisstaub N.V., López-Giménez J.F., Zhou M., Okawa Y., Callado L.F., Milligan G., Gingrich J.A., Filizola M., Meana J.J., Sealfon S.C. Identification of a serotonin/glutamate receptor complex implicated in psychosis (англ.) // Nature : journal. — 2008. — Vol. 452, no. 7183. — P. 93—97. — doi:10.1038/nature06612. — PMID18297054. — PMC2743172.
Moreno J.L., Holloway T., Albizu L., Sealfon S.C., González-Maeso J. Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists (англ.) // Neuroscience Letters[англ.] : journal. — 2011. — Vol. 493, no. 3. — P. 76—79. — doi:10.1016/j.neulet.2011.01.046. — PMID21276828. — PMC3064746.
Wingen M., Kuypers K.P., Ramaekers J.G. The role of 5-HT1a and 5-HT2a receptors in attention and motor control: a mechanistic study in healthy volunteers (англ.) // Psychopharmacology[англ.] : journal. — Springer, 2007. — Vol. 190, no. 3. — P. 391—400. — doi:10.1007/s00213-006-0614-x. — PMID17124621.
Wingen M., Kuypers K.P., Ramaekers J.G. Selective verbal and spatial memory impairment after 5-HT1A and 5-HT2A receptor blockade in healthy volunteers pre-treated with an SSRI (англ.) // J. Psychopharmacol. (Oxford)[англ.] : journal. — 2007. — Vol. 21, no. 5. — P. 477—485. — doi:10.1177/0269881106072506. — PMID17092965.
Gatch M.B., Kozlenkov A., Huang R.Q., Yang W., Nguyen J.D., González-Maeso J., Rice K.C., France C.P., Dillon G.H., Forster M.J., Schetz J.A. The HIV Antiretroviral Drug Efavirenz has LSD-Like Properties (англ.) // Neuropsychopharmacology[англ.] : journal. — Nature Publishing Group, 2013. — Vol. 38, no. 12. — P. 2373—2384. — doi:10.1038/npp.2013.135. — PMID23702798.
Janowsky A., Eshleman A.J., Johnson R.A., Wolfrum K.M., Hinrichs D.J., Yang J., Zabriskie T.M., Smilkstein M.J., Riscoe M.K. Mefloquine and psychotomimetics share neurotransmitter receptor and transporter interactions in vitro (англ.) // Psychopharmacology[англ.] : journal. — Springer, 2014. — Vol. 231, no. 14. — P. 2771—2783. — doi:10.1007/s00213-014-3446-0. — PMID24488404.
Egan C.T., Herrick-Davis K., Miller K., Glennon R.A., Teitler M. Agonist activity of LSD and lisuride at cloned 5HT2A and 5HT2C receptors (англ.) // Psychopharmacology[англ.] : journal. — Springer, 1998. — April (vol. 136, no. 4). — P. 409—414. — doi:10.1007/s002130050585. — PMID9600588.
Sharif N.A., McLaughlin M.A., Kelly C.R. AL-34662: a potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist (англ.) // Journal of Ocular Pharmacology and Therapeutics : journal. — 2007. — February (vol. 23, no. 1). — P. 1—13. — doi:10.1089/jop.2006.0093. — PMID17341144.
May J.A., Dantanarayana A.P., Zinke P.W., McLaughlin M.A., Sharif N.A. 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity (англ.) // Journal of Medicinal Chemistry[англ.] : journal. — 2006. — January (vol. 49, no. 1). — P. 318—328. — doi:10.1021/jm050663x. — PMID16392816.
Shireman B.T., Dvorak C.A., Rudolph D.A., Bonaventure P., Nepomuceno D., Dvorak L., Miller K.L., Lovenberg T.W., Carruthers N.I. 2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists (англ.) // Bioorganic & Medicinal Chemistry Letters[англ.] : journal. — 2008. — March (vol. 18, no. 6). — P. 2103—2108. — doi:10.1016/j.bmcl.2008.01.090. — PMID18282705.
Westkaemper R.B., Runyon S.P., Bondarev M.L., Savage J.E., Roth B.L., Glennon R.A. 9-(Aminomethyl)-9,10-dihydroanthracene is a novel and unlikely 5-HT2A receptor antagonist (англ.) // Eur. J. Pharmacol.[англ.] : journal. — 1999. — September (vol. 380, no. 1). — P. R5—7. — doi:10.1016/S0014-2999(99)00525-7. — PMID10513561.
Westkaemper R.B., Glennon R.A. Application of ligand SAR, receptor modeling and receptor mutagenesis to the discovery and development of a new class of 5-HT2A ligands (англ.) // Curr Top Med Chem[англ.] : journal. — 2002. — June (vol. 2, no. 6). — P. 575—598. — doi:10.2174/1568026023393741. — PMID12052195.
Runyon S.P., Mosier P.D., Roth B.L., Glennon R.A., Westkaemper R.B. Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation (англ.) // J. Med. Chem.[англ.] : journal. — 2008. — November (vol. 51, no. 21). — P. 6808—6828. — doi:10.1021/jm800771x. — PMID18847250. — PMC3088499.
Wilson K.J., van Niel M.B., Cooper L., Bloomfield D., O'Connor D., Fish L.R., MacLeod A.M. 2,5-Disubstituted pyridines: the discovery of a novel series of 5-HT2A ligands (англ.) // Bioorg. Med. Chem. Lett.[англ.] : journal. — 2007. — May (vol. 17, no. 9). — P. 2643—2648. — doi:10.1016/j.bmcl.2007.01.098. — PMID17314044.
Vanover K.E., Harvey S.C., Son T., Bradley S.R., Kold H., Makhay M., Veinbergs I., Spalding T.A., Weiner D.M., Andersson C.M., Tolf B.R., Brann M.R., Hacksell U., Davis R.E. Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2004. — September (vol. 310, no. 3). — P. 943—951. — doi:10.1124/jpet.104.066688. — PMID15102927.
Rosenberg R., Seiden D.J., Hull S.G., Erman M., Schwartz H., Anderson C., Prosser W., Shanahan W., Sanchez M., Chuang E., Roth T. APD125, a selective serotonin 5-HT2A receptor inverse agonist, significantly improves sleep maintenance in primary insomnia (англ.) // Sleep : journal. — 2008. — Vol. 31, no. 12. — P. 1663—1671. — PMID19090322. — PMC2603489.
Vanover K.E., Weiner D.M., Makhay M., Veinbergs I., Gardell L.R., Lameh J., Del Tredici A.L., Piu F., Schiffer H.H., Ott T.R., Burstein E.S., Uldam A.K., Thygesen M.B., Schlienger N., Andersson C.M., Son T.Y., Harvey S.C., Powell S.B., Geyer M.A., Tolf B.R., Brann M.R., Davis R.E. Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2006. — May (vol. 317, no. 2). — P. 910—918. — doi:10.1124/jpet.105.097006. — PMID16469866.
Gardell L.R., Vanover K.E., Pounds L., Johnson R.W., Barido R., Anderson G.T., Veinbergs I., Dyssegaard A., Brunmark P., Tabatabaei A., Davis R.E., Brann M.R., Hacksell U., Bonhaus D.W. ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2007. — August (vol. 322, no. 2). — P. 862—870. — doi:10.1124/jpet.107.121715. — PMID17519387.
Vanover K.E., Betz A.J., Weber S.M., Bibbiani F., Kielaite A., Weiner D.M., Davis R.E., Chase T.N., Salamone J.D. A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model (англ.) // Pharmacol. Biochem. Behav.[англ.] : journal. — 2008. — October (vol. 90, no. 4). — P. 540—544. — doi:10.1016/j.pbb.2008.04.010. — PMID18534670. — PMC2806670.
Abbas A., Roth B.L. Pimavanserin tartrate: a 5-HT2A inverse agonist with potential for treating various neuropsychiatric disorders (англ.) // Expert Opin Pharmacother[англ.] : journal. — 2008. — December (vol. 9, no. 18). — P. 3251—3259. — doi:10.1517/14656560802532707. — PMID19040345.
Moya P.R., Berg K.A., Gutiérrez-Hernandez M.A., Sáez-Briones P., Reyes-Parada M., Cassels B.K., Clarke W.P. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine 5-HT2A and 5-HT2C receptors (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2007. — Vol. 321, no. 3. — P. 1054—1061. — doi:10.1124/jpet.106.117507. — PMID17337633.
González-Maeso J., Weisstaub N.V., Zhou M., Chan P., Ivic L., Ang R., Lira A., Bradley-Moore M., Ge Y., Zhou Q., Sealfon S.C., Gingrich J.A. Hallucinogens recruit specific cortical 5-HT2A receptor-mediated signaling pathways to affect behavior (англ.) // Neuron : journal. — Cell Press, 2007. — Vol. 53, no. 3. — P. 439—452. — doi:10.1016/j.neuron.2007.01.008. — PMID17270739.
Cussac D., Boutet-Robinet E., Ailhaud M.C., Newman-Tancredi A., Martel J.C., Danty N., Rauly-Lestienne I. Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells (англ.) // Eur. J. Pharmacol.[англ.] : journal. — 2008. — October (vol. 594, no. 1—3). — P. 32—8. — doi:10.1016/j.ejphar.2008.07.040. — PMID18703043.
Choi M.J., Lee H.J., Lee H.J., Ham B.J., Cha J.H., Ryu S.H., Lee M.S. Association between major depressive disorder and the -1438A/G polymorphism of the serotonin 2A receptor gene (англ.) // Neuropsychobiology[англ.] : journal. — 2004. — Vol. 49, no. 1. — P. 38—41. — doi:10.1159/000075337. — PMID14730199.
Williams J., Spurlock G., McGuffin P., Mallet J., Nöthen M.M., Gill M., Aschauer H., Nylander P.O., Macciardi F., Owen M.J. Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. European Multicentre Association Study of Schizophrenia (EMASS) Group (англ.) // The Lancet : journal. — Elsevier, 1996. — Vol. 347, no. 9011. — P. 1294—1296. — doi:10.1016/s0140-6736(96)90939-3. — PMID8622505.
Vaquero-Lorenzo C., Baca-Garcia E., Diaz-Hernandez M., Perez-Rodriguez M.M., Fernandez-Navarro P., Giner L., Carballo J.J., Saiz-Ruiz J., Fernandez-Piqueras J., Baldomero E.B., de Leon J., Oquendo M.A. Association study of two polymorphisms of the serotonin-2A receptor gene and suicide attempts (англ.) // American Journal of Medical Genetics[англ.] : journal. — 2008. — July (vol. 147B, no. 5). — P. 645—649. — doi:10.1002/ajmg.b.30642. — PMID18163387.
Serretti A., Drago A., De Ronchi D. HTR2A gene variants and psychiatric disorders: a review of current literature and selection of SNPs for future studies (англ.) // Current medicinal chemistry[англ.] : journal. — 2007. — Vol. 14, no. 19. — P. 2053—2069. — doi:10.2174/092986707781368450. — PMID17691947.
McMahon F.J., Buervenich S., Charney D., Lipsky R., Rush A.J., Wilson A.F., Sorant A.J., Papanicolaou G.J., Laje G., Fava M., Trivedi M.H., Wisniewski S.R., Manji H. Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment (англ.) // Am. J. Hum. Genet.[англ.] : journal. — 2006. — Vol. 78, no. 5. — P. 804—814. — doi:10.1086/503820. — PMID16642436. — PMC1474035.
Smith A.K., Dimulescu I., Falkenberg V.R., Narasimhan S., Heim C., Vernon S.D., Rajeevan M.S. Genetic evaluation of the serotonergic system in chronic fatigue syndrome (англ.) // Psychoneuroendocrinology : journal. — 2008. — Vol. 33, no. 2. — P. 188—197. — doi:10.1016/j.psyneuen.2007.11.001. — PMID18079067.
Haugbøl S., Pinborg L.H., Regeur L., Hansen E.S., Bolwig T.G., Nielsen F.A., Svarer C., Skovgaard L.T., Knudsen G.M. Cerebral 5-HT2A receptor binding is increased in patients with Tourette's syndrome (англ.) // Int. J. Neuropsychopharmacol.[англ.] : journal. — 2007. — Vol. 10, no. 2. — P. 245—252. — doi:10.1017/S1461145706006559. — PMID16945163.
Rosier A., Dupont P., Peuskens J., Bormans G., Vandenberghe R., Maes M., de Groot T., Schiepers C., Verbruggen A., Mortelmans L. Visualisation of loss of 5-HT2A receptors with age in healthy volunteers using [18F]-altanserin and positron emission tomographic imaging (англ.) // Psychiatry Res.[англ.] : journal. — 1996. — Vol. 68, no. 1. — P. 11—22. — doi:10.1016/S0925-4927(96)02806-5. — PMID9027929.
Meltzer C.C., Smith G., Price J.C., Reynolds C.F., Mathis C.A., Greer P., Lopresti B., Mintun M.A., Pollock B.G., Ben-Eliezer D., Cantwell M.N., Kaye W., DeKosky S.T. Reduced binding of [18F]-altanserin to serotonin type 2A receptors in aging: persistence of effect after partial volume correction (англ.) // Brain Res.[англ.] : journal. — 1998. — Vol. 813, no. 1. — P. 167—171. — doi:10.1016/S0006-8993(98)00909-3. — PMID9824691.
Adams K.H., Pinborg L.H., Svarer C., Hasselbalch S.G., Holm S., Haugbøl S., Madsen K., Frøkjaer V., Martiny L., Paulson O.B., Knudsen G.M. A database of [18F]-altanserin binding to 5-HT2A receptors in normal volunteers: normative data and relationship to physiological and demographic variables (англ.) // NeuroImage[англ.] : journal. — 2004. — Vol. 21, no. 3. — P. 1105—1113. — doi:10.1016/j.neuroimage.2003.10.046. — PMID15006678.
Cook E.H., Fletcher K.E., Wainwright M., Marks N., Yan S.Y., Leventhal B.L. Primary structure of the human platelet serotonin 5-HT2 receptor: identity with frontal cortex serotonin 5-HT2A receptor (англ.) // J. Neurochem.[англ.] : journal. — 1994. — August (vol. 63, no. 2). — P. 465—469. — doi:10.1046/j.1471-4159.1994.63020465.x. — PMID8035173.
Martin P., Waters N., Schmidt C.J., Carlsson A., Carlsson M.L. Rodent data and general hypothesis: antipsychotic action exerted through 5-HT2A receptor antagonism is dependent on increased serotonergic tone (англ.) // J Neural Transm[англ.] : journal. — 1998. — Vol. 105, no. 4—5. — P. 365—396. — doi:10.1007/s007020050064. — PMID9720968.
Aghajanian G.K., Marek G.J. Serotonin, via 5-HT2A receptors, increases EPSCs in layer V pyramidal cells of prefrontal cortex by an asynchronous mode of glutamate release (англ.) // Brain Res.[англ.] : journal. — 1999. — April (vol. 825, no. 1—2). — P. 161—171. — doi:10.1016/S0006-8993(99)01224-X. — PMID10216183.
Marek G.J., Wright R.A., Gewirtz J.C., Schoepp D.D. A major role for thalamocortical afferents in serotonergic hallucinogen receptor function in the rat neocortex (англ.) // Neuroscience[англ.] : journal. — Elsevier, 2001. — Vol. 105, no. 2. — P. 379—392. — doi:10.1016/S0306-4522(01)00199-3. — PMID11672605.
Bortolozzi A., Díaz-Mataix L., Scorza M.C., Celada P., Artigas F. The activation of 5-HT receptors in prefrontal cortex enhances dopaminergic activity (англ.) // J. Neurochem.[англ.] : journal. — 2005. — December (vol. 95, no. 6). — P. 1597—1607. — doi:10.1111/j.1471-4159.2005.03485.x. — PMID16277612.
Amargós-Bosch M., Bortolozzi A., Puig M.V., Serrats J., Adell A., Celada P., Toth M., Mengod G., Artigas F. Co-expression and in vivo interaction of serotonin1A and serotonin2A receptors in pyramidal neurons of prefrontal cortex (англ.) // Cereb. Cortex[англ.] : journal. — 2004. — March (vol. 14, no. 3). — P. 281—299. — doi:10.1093/cercor/bhg128. — PMID14754868.
Marek G.J., Zhang C. Activation of metabotropic glutamate 5 (mGlu5) receptors induces spontaneous excitatory synaptic currents in layer V pyramidal cells of the rat prefrontal cortex (англ.) // Neurosci. Lett.[англ.] : journal. — 2008. — September (vol. 442, no. 3). — P. 239—243. — doi:10.1016/j.neulet.2008.06.083. — PMID18621097. — PMC2677702.
Maeshima T., Shutoh F., Hamada S., Senzaki K., Hamaguchi-Hamada K., Ito R., Okado N. Serotonin2A receptor-like immunoreactivity in rat cerebellar Purkinje cells (англ.) // Neurosci. Lett.[англ.] : journal. — 1998. — August (vol. 252, no. 1). — P. 72—74. — doi:10.1016/S0304-3940(98)00546-1. — PMID9756362.
Dürk T., Panther E., Müller T., Sorichter S., Ferrari D., Pizzirani C., Di Virgilio F., Myrtek D., Norgauer J., Idzko M. 5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes (англ.) // Int Immunol[англ.] : journal. — 2005. — May (vol. 17, no. 5). — P. 599—606. — doi:10.1093/intimm/dxh242. — PMID15802305.
Zhang Y., Damjanoska K. J., Carrasco G. A., Dudas B., D'Souza D. N., Tetzlaff J., Garcia F., Hanley N. R., Scripathirathan K., Petersen B. R., Gray T. S., Battaglia G., Muma N. A., Van de Kar L. D. Evidence that 5-HT2A receptors in the hypothalamic paraventricular nucleus mediate neuroendocrine responses to (-)DOI (англ.) // J Neurosci.[англ.] : journal. — 2002. — November (vol. 22, no. 21). — P. 9635—9642. — PMID12417689.
Bortolozzi A., Díaz-Mataix L., Scorza M. C., Celada P., Artigas F. The activation of 5-HT receptors in prefrontal cortex enhances dopaminergic activity (англ.) // J. Neurochem.[англ.] : journal. — 2005. — Vol. 95, no. 6. — P. 1597—1607. — doi:10.1111/j.1471-4159.2005.03485.x. — PMID16277612.
Williams G. V., Rao S. G., Goldman-Rakic P. S. The physiological role of 5-HT2A receptors in working memory (англ.) // J. Neurosci.[англ.] : journal. — 2002. — Vol. 22, no. 7. — P. 2843—2854. — PMID11923449.
Blaazer A.R., Smid P., Kruse C.G. Structure-activity relationships of phenylalkylamines as agonist ligands for 5-HT(2A) receptors (англ.) // ChemMedChem[англ.] : journal. — 2008. — Vol. 3, no. 9. — P. 1299—1309. — doi:10.1002/cmdc.200800133. — PMID18666267.
Moreno J.L., Holloway T., Albizu L., Sealfon S.C., González-Maeso J. Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists (англ.) // Neuroscience Letters[англ.] : journal. — 2011. — Vol. 493, no. 3. — P. 76—79. — doi:10.1016/j.neulet.2011.01.046. — PMID21276828. — PMC3064746.
Wingen M., Kuypers K.P., Ramaekers J.G. The role of 5-HT1a and 5-HT2a receptors in attention and motor control: a mechanistic study in healthy volunteers (англ.) // Psychopharmacology[англ.] : journal. — Springer, 2007. — Vol. 190, no. 3. — P. 391—400. — doi:10.1007/s00213-006-0614-x. — PMID17124621.
Wingen M., Kuypers K.P., Ramaekers J.G. Selective verbal and spatial memory impairment after 5-HT1A and 5-HT2A receptor blockade in healthy volunteers pre-treated with an SSRI (англ.) // J. Psychopharmacol. (Oxford)[англ.] : journal. — 2007. — Vol. 21, no. 5. — P. 477—485. — doi:10.1177/0269881106072506. — PMID17092965.
Gatch M.B., Kozlenkov A., Huang R.Q., Yang W., Nguyen J.D., González-Maeso J., Rice K.C., France C.P., Dillon G.H., Forster M.J., Schetz J.A. The HIV Antiretroviral Drug Efavirenz has LSD-Like Properties (англ.) // Neuropsychopharmacology[англ.] : journal. — Nature Publishing Group, 2013. — Vol. 38, no. 12. — P. 2373—2384. — doi:10.1038/npp.2013.135. — PMID23702798.
Janowsky A., Eshleman A.J., Johnson R.A., Wolfrum K.M., Hinrichs D.J., Yang J., Zabriskie T.M., Smilkstein M.J., Riscoe M.K. Mefloquine and psychotomimetics share neurotransmitter receptor and transporter interactions in vitro (англ.) // Psychopharmacology[англ.] : journal. — Springer, 2014. — Vol. 231, no. 14. — P. 2771—2783. — doi:10.1007/s00213-014-3446-0. — PMID24488404.
Egan C.T., Herrick-Davis K., Miller K., Glennon R.A., Teitler M. Agonist activity of LSD and lisuride at cloned 5HT2A and 5HT2C receptors (англ.) // Psychopharmacology[англ.] : journal. — Springer, 1998. — April (vol. 136, no. 4). — P. 409—414. — doi:10.1007/s002130050585. — PMID9600588.
Shireman B.T., Dvorak C.A., Rudolph D.A., Bonaventure P., Nepomuceno D., Dvorak L., Miller K.L., Lovenberg T.W., Carruthers N.I. 2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists (англ.) // Bioorganic & Medicinal Chemistry Letters[англ.] : journal. — 2008. — March (vol. 18, no. 6). — P. 2103—2108. — doi:10.1016/j.bmcl.2008.01.090. — PMID18282705.
Westkaemper R.B., Runyon S.P., Bondarev M.L., Savage J.E., Roth B.L., Glennon R.A. 9-(Aminomethyl)-9,10-dihydroanthracene is a novel and unlikely 5-HT2A receptor antagonist (англ.) // Eur. J. Pharmacol.[англ.] : journal. — 1999. — September (vol. 380, no. 1). — P. R5—7. — doi:10.1016/S0014-2999(99)00525-7. — PMID10513561.
Westkaemper R.B., Glennon R.A. Application of ligand SAR, receptor modeling and receptor mutagenesis to the discovery and development of a new class of 5-HT2A ligands (англ.) // Curr Top Med Chem[англ.] : journal. — 2002. — June (vol. 2, no. 6). — P. 575—598. — doi:10.2174/1568026023393741. — PMID12052195.
Runyon S.P., Mosier P.D., Roth B.L., Glennon R.A., Westkaemper R.B. Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation (англ.) // J. Med. Chem.[англ.] : journal. — 2008. — November (vol. 51, no. 21). — P. 6808—6828. — doi:10.1021/jm800771x. — PMID18847250. — PMC3088499.
Wilson K.J., van Niel M.B., Cooper L., Bloomfield D., O'Connor D., Fish L.R., MacLeod A.M. 2,5-Disubstituted pyridines: the discovery of a novel series of 5-HT2A ligands (англ.) // Bioorg. Med. Chem. Lett.[англ.] : journal. — 2007. — May (vol. 17, no. 9). — P. 2643—2648. — doi:10.1016/j.bmcl.2007.01.098. — PMID17314044.
Vanover K.E., Harvey S.C., Son T., Bradley S.R., Kold H., Makhay M., Veinbergs I., Spalding T.A., Weiner D.M., Andersson C.M., Tolf B.R., Brann M.R., Hacksell U., Davis R.E. Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2004. — September (vol. 310, no. 3). — P. 943—951. — doi:10.1124/jpet.104.066688. — PMID15102927.
Vanover K.E., Weiner D.M., Makhay M., Veinbergs I., Gardell L.R., Lameh J., Del Tredici A.L., Piu F., Schiffer H.H., Ott T.R., Burstein E.S., Uldam A.K., Thygesen M.B., Schlienger N., Andersson C.M., Son T.Y., Harvey S.C., Powell S.B., Geyer M.A., Tolf B.R., Brann M.R., Davis R.E. Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2006. — May (vol. 317, no. 2). — P. 910—918. — doi:10.1124/jpet.105.097006. — PMID16469866.
Gardell L.R., Vanover K.E., Pounds L., Johnson R.W., Barido R., Anderson G.T., Veinbergs I., Dyssegaard A., Brunmark P., Tabatabaei A., Davis R.E., Brann M.R., Hacksell U., Bonhaus D.W. ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2007. — August (vol. 322, no. 2). — P. 862—870. — doi:10.1124/jpet.107.121715. — PMID17519387.
Vanover K.E., Betz A.J., Weber S.M., Bibbiani F., Kielaite A., Weiner D.M., Davis R.E., Chase T.N., Salamone J.D. A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model (англ.) // Pharmacol. Biochem. Behav.[англ.] : journal. — 2008. — October (vol. 90, no. 4). — P. 540—544. — doi:10.1016/j.pbb.2008.04.010. — PMID18534670. — PMC2806670.
Abbas A., Roth B.L. Pimavanserin tartrate: a 5-HT2A inverse agonist with potential for treating various neuropsychiatric disorders (англ.) // Expert Opin Pharmacother[англ.] : journal. — 2008. — December (vol. 9, no. 18). — P. 3251—3259. — doi:10.1517/14656560802532707. — PMID19040345.
Moya P.R., Berg K.A., Gutiérrez-Hernandez M.A., Sáez-Briones P., Reyes-Parada M., Cassels B.K., Clarke W.P. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine 5-HT2A and 5-HT2C receptors (англ.) // J. Pharmacol. Exp. Ther.[англ.] : journal. — 2007. — Vol. 321, no. 3. — P. 1054—1061. — doi:10.1124/jpet.106.117507. — PMID17337633.
Cussac D., Boutet-Robinet E., Ailhaud M.C., Newman-Tancredi A., Martel J.C., Danty N., Rauly-Lestienne I. Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells (англ.) // Eur. J. Pharmacol.[англ.] : journal. — 2008. — October (vol. 594, no. 1—3). — P. 32—8. — doi:10.1016/j.ejphar.2008.07.040. — PMID18703043.
Parker M.A., Kurrasch D.M., Nichols D.E. The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands (англ.) // Bioorg. Med. Chem.[англ.] : journal. — 2008. — Vol. 16, no. 8. — P. 4661—4669. — doi:10.1016/j.bmc.2008.02.033. — PMID18296055. — PMC2442558.
Choi M.J., Lee H.J., Lee H.J., Ham B.J., Cha J.H., Ryu S.H., Lee M.S. Association between major depressive disorder and the -1438A/G polymorphism of the serotonin 2A receptor gene (англ.) // Neuropsychobiology[англ.] : journal. — 2004. — Vol. 49, no. 1. — P. 38—41. — doi:10.1159/000075337. — PMID14730199.
Vaquero-Lorenzo C., Baca-Garcia E., Diaz-Hernandez M., Perez-Rodriguez M.M., Fernandez-Navarro P., Giner L., Carballo J.J., Saiz-Ruiz J., Fernandez-Piqueras J., Baldomero E.B., de Leon J., Oquendo M.A. Association study of two polymorphisms of the serotonin-2A receptor gene and suicide attempts (англ.) // American Journal of Medical Genetics[англ.] : journal. — 2008. — July (vol. 147B, no. 5). — P. 645—649. — doi:10.1002/ajmg.b.30642. — PMID18163387.
Serretti A., Drago A., De Ronchi D. HTR2A gene variants and psychiatric disorders: a review of current literature and selection of SNPs for future studies (англ.) // Current medicinal chemistry[англ.] : journal. — 2007. — Vol. 14, no. 19. — P. 2053—2069. — doi:10.2174/092986707781368450. — PMID17691947.
McMahon F.J., Buervenich S., Charney D., Lipsky R., Rush A.J., Wilson A.F., Sorant A.J., Papanicolaou G.J., Laje G., Fava M., Trivedi M.H., Wisniewski S.R., Manji H. Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment (англ.) // Am. J. Hum. Genet.[англ.] : journal. — 2006. — Vol. 78, no. 5. — P. 804—814. — doi:10.1086/503820. — PMID16642436. — PMC1474035.
Haugbøl S., Pinborg L.H., Regeur L., Hansen E.S., Bolwig T.G., Nielsen F.A., Svarer C., Skovgaard L.T., Knudsen G.M. Cerebral 5-HT2A receptor binding is increased in patients with Tourette's syndrome (англ.) // Int. J. Neuropsychopharmacol.[англ.] : journal. — 2007. — Vol. 10, no. 2. — P. 245—252. — doi:10.1017/S1461145706006559. — PMID16945163.
Rosier A., Dupont P., Peuskens J., Bormans G., Vandenberghe R., Maes M., de Groot T., Schiepers C., Verbruggen A., Mortelmans L. Visualisation of loss of 5-HT2A receptors with age in healthy volunteers using [18F]-altanserin and positron emission tomographic imaging (англ.) // Psychiatry Res.[англ.] : journal. — 1996. — Vol. 68, no. 1. — P. 11—22. — doi:10.1016/S0925-4927(96)02806-5. — PMID9027929.
Meltzer C.C., Smith G., Price J.C., Reynolds C.F., Mathis C.A., Greer P., Lopresti B., Mintun M.A., Pollock B.G., Ben-Eliezer D., Cantwell M.N., Kaye W., DeKosky S.T. Reduced binding of [18F]-altanserin to serotonin type 2A receptors in aging: persistence of effect after partial volume correction (англ.) // Brain Res.[англ.] : journal. — 1998. — Vol. 813, no. 1. — P. 167—171. — doi:10.1016/S0006-8993(98)00909-3. — PMID9824691.
Adams K.H., Pinborg L.H., Svarer C., Hasselbalch S.G., Holm S., Haugbøl S., Madsen K., Frøkjaer V., Martiny L., Paulson O.B., Knudsen G.M. A database of [18F]-altanserin binding to 5-HT2A receptors in normal volunteers: normative data and relationship to physiological and demographic variables (англ.) // NeuroImage[англ.] : journal. — 2004. — Vol. 21, no. 3. — P. 1105—1113. — doi:10.1016/j.neuroimage.2003.10.046. — PMID15006678.