cDNA cloning and functional expression of a human monocyte chemoattractant protein 1 receptor. Yamagami S, Tokuda Y, Ishii K, Tanaka H, Endo N. Biochem Biophys Res Commun. 1994 Jul 29;202(2):1156-62. doi:10.1006/bbrc.1994.2049.
The amino-terminal domain of the CCR2 chemokine receptor acts as coreceptor for HIV-1 infection. Frade JM, Llorente M, Mellado M, Alcamí J, Gutiérrez-Ramos JC, Zaballos A, Real G, Martínez-A C. J Clin Invest. 1997 Aug 1;100(3):497-502. doi:10.1172/JCI119558.
Chronic inflammation upregulates chemokine receptors and induces neutrophil migration to monocyte chemoattractant protein-1. Johnston B, Burns AR, Suematsu M, Issekutz TB, Woodman RC, Kubes P. J Clin Invest. 1999 May;103(9):1269-76. doi:10.1172/JCI5208.
Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Sallusto F, Schaerli P, Loetscher P, Schaniel C, Lenig D, Mackay CR, Qin S, Lanzavecchia A. Eur J Immunol. 1998 Sep;28(9):2760-9. doi:10.1002/(SICI)1521-4141(199809)28:09.<2760::AID-IMMU2760>3.0.CO;2-N
Characterization of monocyte chemotactic protein-1 binding to human monocytes. Valente AJ, Rozek MM, Schwartz CJ, Graves DT. Biochem Biophys Res Commun. 1991 Apr 15;176(1):309-14. doi:10.1016/0006-291X(91)90925-W.
Studies of binding and internalization of human recombinant monocyte chemotactic and activating factor (MCAF) by monocytic cells. Wang JM, Hishinuma A, Oppenheim JJ, Matsushima K. Cytokine. 1993 May;5(3):264-75. doi:10.1016/1043-4666(93)90014-V.
Role of the first extracellular loop in the functional activation of CCR2. The first extracellular loop contains distinct domains necessary for both agonist binding and transmembrane signaling. Han KH, Green SR, Tangirala RK, Tanaka S, Quehenberger O. J Biol Chem. 1999 Nov 5;274(45):32055-62. doi:10.1074/jbc.274.45.32055.
Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors. Gong X, Gong W, Kuhns DB, Ben-Baruch A, Howard OM, Wang JM. J Biol Chem. 1997 May 2;272(18):11682-5. doi: 10.1074/jbc.272.18.11682.
Loss of CCR2 expression and functional response to monocyte chemotactic protein (MCP-1) during the differentiation of human monocytes: role of secreted MCP-1 in the regulation of the chemotactic response. Fantuzzi L, Borghi P, Ciolli V, Pavlakis G, Belardelli F, Gessani S. Blood. 1999 Aug 1;94(3):875-83. PMID 10419877
Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling. Rabin RL, Park MK, Liao F, Swofford R, Stephany D, Farber JM. J Immunol. 1999 Apr 1;162(7):3840-50. PMID 10201901
Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. Loetscher P, Seitz M, Baggiolini M, Moser B. J Exp Med. 1996 Aug 1;184(2):569-77. PMID 8760810
Chemokines: function, regulation and alteration of inflammatory responses. Lukacs NW, Hogaboam C, Campbell E, Kunkel SL. Chem Immunol. 1999;72:102-20. PMID 10550933
IL-2-regulated expression of the monocyte chemotactic protein-1 receptor (CCR2) in human NK cells: characterization of a predominant 3.4-kilobase transcript containing CCR2B and CCR2A sequences. Polentarutti N, Allavena P, Bianchi G, Giardina G, Basile A, Sozzani S, Mantovani A, Introna M. J Immunol. 1997 Mar 15;158(6):2689-94. PMID 9058802
MCP-1 and CCR2 in HIV infection: regulation of agonist and receptor expression. Sozzani S, Introna M, Bernasconi S, Polentarutti N, Cinque P, Poli G, Sica A, Mantovani A. J Leukoc Biol. 1997 Jul;62(1):30-3. PMID 9225989
Monocyte chemoattractant protein-1 mediates cockroach allergen-induced bronchial hyperreactivity in normal but not CCR2-/- mice: the role of mast cells. Campbell EM, Charo IF, Kunkel SL, Strieter RM, Boring L, Gosling J, Lukacs NW. J Immunol. 1999 Aug 15;163(4):2160-7. PMID 10438957
Expression of CCR2 by endothelial cells : implications for MCP-1 mediated wound injury repair and In vivo inflammatory activation of endothelium. Weber KS, Nelson PJ, Gröne HJ, Weber C. Arterioscler Thromb Vasc Biol. 1999 Sep;19(9):2085-93. PMID 10479649
Identification of high affinity receptors for human monocyte chemoattractant protein-1 on human monocytes. Yoshimura T, Leonard EJ. J Immunol. 1990 Jul 1;145(1):292-7. PMID 2162890