Rapamycin (Simple English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Rapamycin" in Simple English language version.

Last modified: 15:24:06, 26 July 2026 (UTC)

Ref.Un. Ref.Website

Global rank Simple English rank

2522nih.gov

5^th place

1412doi.org

2^nd place

75adsabs.harvard.edu

14^th place

17^th place

66web.archive.org

1^st place

44europa.eu

62^nd place

106^th place

33semanticscholar.org

15^th place

11^th place

21fda.gov

470^th place

788^th place

11medscape.com

1,078^th place

702^nd place

11archive.org

6^th place

3^rd place

11jst.go.jp

1,248^th place

3,001^st place

11thetimes.co.uk

1,280^th place

322^nd place

11nature.com

207^th place

117^th place

11nytimes.com

7^th place

8^th place

11worldcat.org

4^th place

6^th place

adsabs.harvard.edu (Global: 14^th place; Simple English: 17^th place)

ui.adsabs.harvard.edu

Harrison, David E.; Strong, Randy; Sharp, Zelton Dave; Nelson, James F.; Astle, Clinton M.; Flurkey, Kevin; Nadon, Nancy L.; Wilkinson, J. Erby; Frenkel, Krystyna; Carter, Christy S.; Pahor, Marco; Javors, Martin A.; Fernandez, Elizabeth; Miller, Richard A. (2009). "Rapamycin fed late in life extends lifespan in genetically heterogeneous mice". Nature. 460 (7253): 392–5. Bibcode:2009Natur.460..392H. doi:10.1038/nature08221. PMC 2786175. PMID 19587680.
Check Hayden, Erika 2014. (2014). "Pet dogs set to test anti-ageing drug". Nature. 514 (7524): 546. Bibcode:2014Natur.514..546C. doi:10.1038/514546a. PMID 25355339. S2CID 4470407. Retrieved 2 April 2015.{{cite journal}}: CS1 maint: numeric names: authors list (link)
Cota, Daniela; Proulx, Karine; Smith, Kathi A. Blake; Kozma, Sara C.; Thomas, George; Woods, Stephen C.; Seeley, Randy J. (2006). "Hypothalamic mTOR signaling regulates food intake". Science. 312 (5775): 927–930. Bibcode:2006Sci...312..927C. doi:10.1126/science.1124147. PMID 16690869. S2CID 6526786.
Kriete A; Bosl W.J.; Booker G. (2010). "Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses". PLOS Computational Biology. 6 (6) e1000820. Bibcode:2010PLSCB...6E0820K. doi:10.1371/journal.pcbi.1000820. PMC 2887462. PMID 20585546.
Schieke, Stefan M.; Phillips, Darci; McCoy, J. Philip; Aponte, Angel M.; Shen, Rong-Fong; Balaban, Robert S.; Finkel, Toren (2006). "The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity". J. Biol. Chem. 281 (37): 27643–27652. Bibcode:2006JBiCh.28127643S. doi:10.1074/jbc.M603536200. PMID 16847060.

archive.org (Global: 6^th place; Simple English: 3^rd place)

Simamora P, Alvarez JM, Yalkowsky SH (February 2001). "Solubilization of rapamycin". International Journal of Pharmaceutics. 213 (1–2): 25–29. doi:10.1016/s0378-5173(00)00617-7. PMID 11165091.

doi.org (Global: 2^nd place; Simple English: 2^nd place)

Simamora P, Alvarez JM, Yalkowsky SH (February 2001). "Solubilization of rapamycin". International Journal of Pharmaceutics. 213 (1–2): 25–29. doi:10.1016/s0378-5173(00)00617-7. PMID 11165091.
Vézina, Claude; Kudelski, Alicia; Sehgal, S. N. (1975). "Rapamycin (AY-22,989), a new antifungal antibiotic". J. Antibiot. 28 (10): 721–6. doi:10.7164/antibiotics.28.721. PMID 1102508.
Powers, R. Wilson; Kaeberlein, Matt; Caldwell, Seth D.; Kennedy, Brian K.; Fields, Stanley (2006). "Extension of chronological life span in yeast by decreased TOR pathway signaling". Genes Dev. 20 (2): 174–84. doi:10.1101/gad.1381406. PMC 1356109. PMID 16418483.
Harrison, David E.; Strong, Randy; Sharp, Zelton Dave; Nelson, James F.; Astle, Clinton M.; Flurkey, Kevin; Nadon, Nancy L.; Wilkinson, J. Erby; Frenkel, Krystyna; Carter, Christy S.; Pahor, Marco; Javors, Martin A.; Fernandez, Elizabeth; Miller, Richard A. (2009). "Rapamycin fed late in life extends lifespan in genetically heterogeneous mice". Nature. 460 (7253): 392–5. Bibcode:2009Natur.460..392H. doi:10.1038/nature08221. PMC 2786175. PMID 19587680.
Miller, Richard A.; Harrison, David E.; Astle, C. M.; Baur, Joseph A.; Boyd, Angela Rodriguez; De Cabo, Rafael; Fernandez, Elizabeth; Flurkey, Kevin; Javors, Martin A.; Nelson, James F.; Orihuela, Carlos J.; Pletcher, Scott; Sharp, Zelton Dave; Sinclair, David; Starnes, Joseph W.; Wilkinson, J. Erby; Nadon, Nancy L.; Strong, Randy (2011). "Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice". J. Gerontol. A Biol. Sci. Med. Sci. 66 (2): 191–201. doi:10.1093/gerona/glq178. PMC 3021372. PMID 20974732.
Ingram, Donald K.; Roth, George S. (2011). "Glycolytic inhibition as a strategy for developing calorie restriction mimetics". Experimental Gerontology (review). 46 (2–3): 148–154. doi:10.1016/j.exger.2010.12.001. PMID 21167272. S2CID 5634847.
Tardif, Suzette; Ross, Corinna; Bergman, Phillip; Fernandez, Elizabeth; Javors, Marty; Salmon, Adam; Spross, Jennifer; Strong, Randy; Richardson, Arlan (2015). "Testing efficacy of administration of the antiaging drug rapamycin in a nonhuman primate, the common marmoset". J Gerontol A Biol Sci Med Sci. 70 (5): 577–588. doi:10.1093/gerona/glu101. PMC 4400395. PMID 25038772.
Check Hayden, Erika 2014. (2014). "Pet dogs set to test anti-ageing drug". Nature. 514 (7524): 546. Bibcode:2014Natur.514..546C. doi:10.1038/514546a. PMID 25355339. S2CID 4470407. Retrieved 2 April 2015.{{cite journal}}: CS1 maint: numeric names: authors list (link)
Cota, Daniela; Proulx, Karine; Smith, Kathi A. Blake; Kozma, Sara C.; Thomas, George; Woods, Stephen C.; Seeley, Randy J. (2006). "Hypothalamic mTOR signaling regulates food intake". Science. 312 (5775): 927–930. Bibcode:2006Sci...312..927C. doi:10.1126/science.1124147. PMID 16690869. S2CID 6526786.
Kriete A; Bosl W.J.; Booker G. (2010). "Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses". PLOS Computational Biology. 6 (6) e1000820. Bibcode:2010PLSCB...6E0820K. doi:10.1371/journal.pcbi.1000820. PMC 2887462. PMID 20585546.
Magnuson, Brian; Ekim, Bilgen; Fingar, Diane C. (2012). "Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks". The Biochemical Journal. 441 (1): 1–21. doi:10.1042/BJ20110892. ISSN 1470-8728. PMID 22168436.
Schieke, Stefan M.; Phillips, Darci; McCoy, J. Philip; Aponte, Angel M.; Shen, Rong-Fong; Balaban, Robert S.; Finkel, Toren (2006). "The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity". J. Biol. Chem. 281 (37): 27643–27652. Bibcode:2006JBiCh.28127643S. doi:10.1074/jbc.M603536200. PMID 16847060.

europa.eu (Global: 62^nd place; Simple English: 106^th place)

ema.europa.eu

"Rapamune EPAR". European Medicines Agency. 17 September 2018. Archived from the original on 13 August 2021. Retrieved 26 November 2021.
"Hyftor EPAR". European Medicines Agency (EMA). 9 June 2023. Retrieved 12 June 2023. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.

ec.europa.eu

"Rapamune Product information". Union Register of medicinal products. 15 March 2001. Retrieved 23 March 2025.
"Hyftor Product information". Union Register of medicinal products. 26 May 2023. Retrieved 23 March 2025.

fda.gov (Global: 470^th place; Simple English: 788^th place)

accessdata.fda.gov

"Rapamune Prescribing Information" (PDF). United States Food and Drug Administration. Wyeth Pharmaceuticals, Inc. May 2015.

jst.go.jp (Global: 1,248^th place; Simple English: 3,001^st place)

joi.jlc.jst.go.jp

Vézina, Claude; Kudelski, Alicia; Sehgal, S. N. (1975). "Rapamycin (AY-22,989), a new antifungal antibiotic". J. Antibiot. 28 (10): 721–6. doi:10.7164/antibiotics.28.721. PMID 1102508.

medscape.com (Global: 1,078^th place; Simple English: 702^nd place)

Buck ML (2006). "Immunosuppression With Sirolimus After Solid Organ Transplantation in Children". Pediatric Pharmacotherapy. 12 (2). Archived from the original on 18 April 2020. Retrieved 4 April 2022.

nature.com (Global: 207^th place; Simple English: 117^th place)

Check Hayden, Erika 2014. (2014). "Pet dogs set to test anti-ageing drug". Nature. 514 (7524): 546. Bibcode:2014Natur.514..546C. doi:10.1038/514546a. PMID 25355339. S2CID 4470407. Retrieved 2 April 2015.{{cite journal}}: CS1 maint: numeric names: authors list (link)

nih.gov (Global: 5^th place; Simple English: 5^th place)

pubmed.ncbi.nlm.nih.gov

Simamora P, Alvarez JM, Yalkowsky SH (February 2001). "Solubilization of rapamycin". International Journal of Pharmaceutics. 213 (1–2): 25–29. doi:10.1016/s0378-5173(00)00617-7. PMID 11165091.
Vézina, Claude; Kudelski, Alicia; Sehgal, S. N. (1975). "Rapamycin (AY-22,989), a new antifungal antibiotic". J. Antibiot. 28 (10): 721–6. doi:10.7164/antibiotics.28.721. PMID 1102508.
Powers, R. Wilson; Kaeberlein, Matt; Caldwell, Seth D.; Kennedy, Brian K.; Fields, Stanley (2006). "Extension of chronological life span in yeast by decreased TOR pathway signaling". Genes Dev. 20 (2): 174–84. doi:10.1101/gad.1381406. PMC 1356109. PMID 16418483.
Harrison, David E.; Strong, Randy; Sharp, Zelton Dave; Nelson, James F.; Astle, Clinton M.; Flurkey, Kevin; Nadon, Nancy L.; Wilkinson, J. Erby; Frenkel, Krystyna; Carter, Christy S.; Pahor, Marco; Javors, Martin A.; Fernandez, Elizabeth; Miller, Richard A. (2009). "Rapamycin fed late in life extends lifespan in genetically heterogeneous mice". Nature. 460 (7253): 392–5. Bibcode:2009Natur.460..392H. doi:10.1038/nature08221. PMC 2786175. PMID 19587680.
Miller, Richard A.; Harrison, David E.; Astle, C. M.; Baur, Joseph A.; Boyd, Angela Rodriguez; De Cabo, Rafael; Fernandez, Elizabeth; Flurkey, Kevin; Javors, Martin A.; Nelson, James F.; Orihuela, Carlos J.; Pletcher, Scott; Sharp, Zelton Dave; Sinclair, David; Starnes, Joseph W.; Wilkinson, J. Erby; Nadon, Nancy L.; Strong, Randy (2011). "Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice". J. Gerontol. A Biol. Sci. Med. Sci. 66 (2): 191–201. doi:10.1093/gerona/glq178. PMC 3021372. PMID 20974732.
Ingram, Donald K.; Roth, George S. (2011). "Glycolytic inhibition as a strategy for developing calorie restriction mimetics". Experimental Gerontology (review). 46 (2–3): 148–154. doi:10.1016/j.exger.2010.12.001. PMID 21167272. S2CID 5634847.
Tardif, Suzette; Ross, Corinna; Bergman, Phillip; Fernandez, Elizabeth; Javors, Marty; Salmon, Adam; Spross, Jennifer; Strong, Randy; Richardson, Arlan (2015). "Testing efficacy of administration of the antiaging drug rapamycin in a nonhuman primate, the common marmoset". J Gerontol A Biol Sci Med Sci. 70 (5): 577–588. doi:10.1093/gerona/glu101. PMC 4400395. PMID 25038772.
Check Hayden, Erika 2014. (2014). "Pet dogs set to test anti-ageing drug". Nature. 514 (7524): 546. Bibcode:2014Natur.514..546C. doi:10.1038/514546a. PMID 25355339. S2CID 4470407. Retrieved 2 April 2015.{{cite journal}}: CS1 maint: numeric names: authors list (link)
Cota, Daniela; Proulx, Karine; Smith, Kathi A. Blake; Kozma, Sara C.; Thomas, George; Woods, Stephen C.; Seeley, Randy J. (2006). "Hypothalamic mTOR signaling regulates food intake". Science. 312 (5775): 927–930. Bibcode:2006Sci...312..927C. doi:10.1126/science.1124147. PMID 16690869. S2CID 6526786.
Kriete A; Bosl W.J.; Booker G. (2010). "Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses". PLOS Computational Biology. 6 (6) e1000820. Bibcode:2010PLSCB...6E0820K. doi:10.1371/journal.pcbi.1000820. PMC 2887462. PMID 20585546.
Magnuson, Brian; Ekim, Bilgen; Fingar, Diane C. (2012). "Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks". The Biochemical Journal. 441 (1): 1–21. doi:10.1042/BJ20110892. ISSN 1470-8728. PMID 22168436.
Schieke, Stefan M.; Phillips, Darci; McCoy, J. Philip; Aponte, Angel M.; Shen, Rong-Fong; Balaban, Robert S.; Finkel, Toren (2006). "The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity". J. Biol. Chem. 281 (37): 27643–27652. Bibcode:2006JBiCh.28127643S. doi:10.1074/jbc.M603536200. PMID 16847060.

ncbi.nlm.nih.gov

Powers, R. Wilson; Kaeberlein, Matt; Caldwell, Seth D.; Kennedy, Brian K.; Fields, Stanley (2006). "Extension of chronological life span in yeast by decreased TOR pathway signaling". Genes Dev. 20 (2): 174–84. doi:10.1101/gad.1381406. PMC 1356109. PMID 16418483.
Harrison, David E.; Strong, Randy; Sharp, Zelton Dave; Nelson, James F.; Astle, Clinton M.; Flurkey, Kevin; Nadon, Nancy L.; Wilkinson, J. Erby; Frenkel, Krystyna; Carter, Christy S.; Pahor, Marco; Javors, Martin A.; Fernandez, Elizabeth; Miller, Richard A. (2009). "Rapamycin fed late in life extends lifespan in genetically heterogeneous mice". Nature. 460 (7253): 392–5. Bibcode:2009Natur.460..392H. doi:10.1038/nature08221. PMC 2786175. PMID 19587680.
Miller, Richard A.; Harrison, David E.; Astle, C. M.; Baur, Joseph A.; Boyd, Angela Rodriguez; De Cabo, Rafael; Fernandez, Elizabeth; Flurkey, Kevin; Javors, Martin A.; Nelson, James F.; Orihuela, Carlos J.; Pletcher, Scott; Sharp, Zelton Dave; Sinclair, David; Starnes, Joseph W.; Wilkinson, J. Erby; Nadon, Nancy L.; Strong, Randy (2011). "Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice". J. Gerontol. A Biol. Sci. Med. Sci. 66 (2): 191–201. doi:10.1093/gerona/glq178. PMC 3021372. PMID 20974732.
Tardif, Suzette; Ross, Corinna; Bergman, Phillip; Fernandez, Elizabeth; Javors, Marty; Salmon, Adam; Spross, Jennifer; Strong, Randy; Richardson, Arlan (2015). "Testing efficacy of administration of the antiaging drug rapamycin in a nonhuman primate, the common marmoset". J Gerontol A Biol Sci Med Sci. 70 (5): 577–588. doi:10.1093/gerona/glu101. PMC 4400395. PMID 25038772.
Kriete A; Bosl W.J.; Booker G. (2010). "Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses". PLOS Computational Biology. 6 (6) e1000820. Bibcode:2010PLSCB...6E0820K. doi:10.1371/journal.pcbi.1000820. PMC 2887462. PMID 20585546.

dailymed.nlm.nih.gov

"Rapamune- sirolimus solution Rapamune- sirolimus tablet, sugar coated". DailyMed. Archived from the original on 27 November 2021. Retrieved 26 November 2021.
"Fyarro- sirolimus injection, powder, lyophilized, for suspension". DailyMed. Archived from the original on 19 December 2021. Retrieved 19 December 2021.
"Hyftor- sirolimus gel". DailyMed. 28 January 2021. Archived from the original on 24 March 2022. Retrieved 23 March 2022.

pubchem.ncbi.nlm.nih.gov

"Rapamycin". PubChem Compound. National Center for Biotechnology Information. Archived from the original on 16 August 2016. Retrieved 1 August 2016.

meshb.nlm.nih.gov

"MeSH Browser". meshb.nlm.nih.gov. Retrieved 2026-04-01.

nytimes.com (Global: 7^th place; Simple English: 8^th place)

Amy, Harmon (16 May 2016). "Dogs test drug aimed at humans' biggest killer: age". The New York Times. Retrieved 18 May 2016.

semanticscholar.org (Global: 15^th place; Simple English: 11^th place)

api.semanticscholar.org

Ingram, Donald K.; Roth, George S. (2011). "Glycolytic inhibition as a strategy for developing calorie restriction mimetics". Experimental Gerontology (review). 46 (2–3): 148–154. doi:10.1016/j.exger.2010.12.001. PMID 21167272. S2CID 5634847.
Check Hayden, Erika 2014. (2014). "Pet dogs set to test anti-ageing drug". Nature. 514 (7524): 546. Bibcode:2014Natur.514..546C. doi:10.1038/514546a. PMID 25355339. S2CID 4470407. Retrieved 2 April 2015.{{cite journal}}: CS1 maint: numeric names: authors list (link)
Cota, Daniela; Proulx, Karine; Smith, Kathi A. Blake; Kozma, Sara C.; Thomas, George; Woods, Stephen C.; Seeley, Randy J. (2006). "Hypothalamic mTOR signaling regulates food intake". Science. 312 (5775): 927–930. Bibcode:2006Sci...312..927C. doi:10.1126/science.1124147. PMID 16690869. S2CID 6526786.

thetimes.co.uk (Global: 1,280^th place; Simple English: 322^nd place)

"The Times & The Sunday Times". www.thetimes.co.uk. Retrieved 2022-03-26.

web.archive.org (Global: 1^st place; Simple English: 1^st place)

"Rapamune- sirolimus solution Rapamune- sirolimus tablet, sugar coated". DailyMed. Archived from the original on 27 November 2021. Retrieved 26 November 2021.
"Fyarro- sirolimus injection, powder, lyophilized, for suspension". DailyMed. Archived from the original on 19 December 2021. Retrieved 19 December 2021.
"Hyftor- sirolimus gel". DailyMed. 28 January 2021. Archived from the original on 24 March 2022. Retrieved 23 March 2022.
"Rapamune EPAR". European Medicines Agency. 17 September 2018. Archived from the original on 13 August 2021. Retrieved 26 November 2021.
Buck ML (2006). "Immunosuppression With Sirolimus After Solid Organ Transplantation in Children". Pediatric Pharmacotherapy. 12 (2). Archived from the original on 18 April 2020. Retrieved 4 April 2022.
"Rapamycin". PubChem Compound. National Center for Biotechnology Information. Archived from the original on 16 August 2016. Retrieved 1 August 2016.

worldcat.org (Global: 4^th place; Simple English: 6^th place)

search.worldcat.org

Magnuson, Brian; Ekim, Bilgen; Fingar, Diane C. (2012). "Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks". The Biochemical Journal. 441 (1): 1–21. doi:10.1042/BJ20110892. ISSN 1470-8728. PMID 22168436.

Rapamycin (Simple English Wikipedia)

adsabs.harvard.edu (Global: 14th place; Simple English: 17th place)

ui.adsabs.harvard.edu

archive.org (Global: 6th place; Simple English: 3rd place)

doi.org (Global: 2nd place; Simple English: 2nd place)

europa.eu (Global: 62nd place; Simple English: 106th place)