Metabotropni glutamatni receptor 1 (Serbian Wikipedia)

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Stephan D, Bon C, Holzwarth JA, Galvan M, Pruss RM (1996). „Human metabotropic glutamate receptor 1: mRNA distribution, chromosome localization and functional expression of two splice variants”. Neuropharmacology. 35 (12): 1649—60. PMID 9076744. doi:10.1016/S0028-3908(96)00108-6.
El-Kouhen O; Lehto, S. G.; Pan, J. B.; et al. (2006). „Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist”. Br. J. Pharmacol. 149 (6): 761—74. PMC 2014656 . PMID 17016515. doi:10.1038/sj.bjp.0706877.

doi.org

Stephan D, Bon C, Holzwarth JA, Galvan M, Pruss RM (1996). „Human metabotropic glutamate receptor 1: mRNA distribution, chromosome localization and functional expression of two splice variants”. Neuropharmacology. 35 (12): 1649—60. PMID 9076744. doi:10.1016/S0028-3908(96)00108-6.
Makoff AJ, Phillips T, Pilling C, Emson P (1997). „Expression of a novel splice variant of human mGluR1 in the cerebellum”. Neuroreport. 8 (13): 2943—7. PMID 9376535. doi:10.1097/00001756-199709080-00027.
Ortiz P, Vanaclocha F, López-Bran E, Esquivias JI, López-Estebaranz JL, Martín-González M, Arrue I, García-Romero D, Ochoa C, González-Perez A, Ruiz A, Real LM (2007). „Genetic analysis of the GRM1 gene in human melanoma susceptibility”. Eur. J. Hum. Genet. 15 (11): 1176—82. PMID 17609672. doi:10.1038/sj.ejhg.5201887.
Hemstapat, K.; de Paulis T; Chen, Y.; et al. (2006). „A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators”. Mol. Pharmacol. 70 (2): 616—26. PMID 16645124. doi:10.1124/mol.105.021857.
Lavreysen, H.; R, Wouters; Bischoff, F.; et al. (2004). „JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist”. Neuropharmacology. 47 (7): 961—72. PMID 15555631. doi:10.1016/j.neuropharm.2004.08.007.
Lavreysen H, Janssen C, Bischoff F, Langlois X, Leysen JE, Lesage AS (2003). „[3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists”. Mol. Pharmacol. 63 (5): 1082—93. PMID 12695537. doi:10.1124/mol.63.5.1082.
Kohara, A.; M, Takahashi; Yatsugi, S.; et al. (2008). „Neuroprotective effects of the selective type 1 metabotropic glutamate receptor antagonist YM-202074 in rat stroke models”. Brain Res. 1191: 168—79. PMID 18164695. doi:10.1016/j.brainres.2007.11.035.
Kohara, A.; Y, Nagakura; Kiso, T.; et al. (2007). „Antinociceptive profile of a selective metabotropic glutamate receptor 1 antagonist YM-230888 in chronic pain rodent models”. Eur. J. Pharmacol. 571 (1): 8—16. PMID 17597604. doi:10.1016/j.ejphar.2007.05.030.
Kohara, A.; T, Toya; Tamura, S.; et al. (2005). „Radioligand binding properties and pharmacological characterization of 6-amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamide (YM-298198), a high-affinity, selective, and noncompetitive antagonist of metabotropic glutamate receptor type 1”. J. Pharmacol. Exp. Ther. 315 (1): 163—9. PMID 15976016. doi:10.1124/jpet.105.087171.
Suzuki, G.; T, Kimura; Satow, A.; et al. (2007). „Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide (FTIDC)”. J. Pharmacol. Exp. Ther. 321 (3): 1144—53. PMID 17360958. doi:10.1124/jpet.106.116574.
El-Kouhen O; Lehto, S. G.; Pan, J. B.; et al. (2006). „Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist”. Br. J. Pharmacol. 149 (6): 761—74. PMC 2014656 . PMID 17016515. doi:10.1038/sj.bjp.0706877.
Vieira E, Huwyler J, Jolidon S, Knoflach F, Mutel V, Wichmann J (2009). „Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers”. Bioorg. Med. Chem. Lett. 19 (6): 1666—9. PMID 19233648. doi:10.1016/j.bmcl.2009.01.108.

nih.gov

ncbi.nlm.nih.gov

„Entrez Gene: GRM1 glutamate receptor, metabotropic 1”.
Stephan D, Bon C, Holzwarth JA, Galvan M, Pruss RM (1996). „Human metabotropic glutamate receptor 1: mRNA distribution, chromosome localization and functional expression of two splice variants”. Neuropharmacology. 35 (12): 1649—60. PMID 9076744. doi:10.1016/S0028-3908(96)00108-6.
Makoff AJ, Phillips T, Pilling C, Emson P (1997). „Expression of a novel splice variant of human mGluR1 in the cerebellum”. Neuroreport. 8 (13): 2943—7. PMID 9376535. doi:10.1097/00001756-199709080-00027.
Ortiz P, Vanaclocha F, López-Bran E, Esquivias JI, López-Estebaranz JL, Martín-González M, Arrue I, García-Romero D, Ochoa C, González-Perez A, Ruiz A, Real LM (2007). „Genetic analysis of the GRM1 gene in human melanoma susceptibility”. Eur. J. Hum. Genet. 15 (11): 1176—82. PMID 17609672. doi:10.1038/sj.ejhg.5201887.
Hemstapat, K.; de Paulis T; Chen, Y.; et al. (2006). „A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators”. Mol. Pharmacol. 70 (2): 616—26. PMID 16645124. doi:10.1124/mol.105.021857.
Lavreysen, H.; R, Wouters; Bischoff, F.; et al. (2004). „JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist”. Neuropharmacology. 47 (7): 961—72. PMID 15555631. doi:10.1016/j.neuropharm.2004.08.007.
Lavreysen H, Janssen C, Bischoff F, Langlois X, Leysen JE, Lesage AS (2003). „[3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists”. Mol. Pharmacol. 63 (5): 1082—93. PMID 12695537. doi:10.1124/mol.63.5.1082.
Kohara, A.; M, Takahashi; Yatsugi, S.; et al. (2008). „Neuroprotective effects of the selective type 1 metabotropic glutamate receptor antagonist YM-202074 in rat stroke models”. Brain Res. 1191: 168—79. PMID 18164695. doi:10.1016/j.brainres.2007.11.035.
Kohara, A.; Y, Nagakura; Kiso, T.; et al. (2007). „Antinociceptive profile of a selective metabotropic glutamate receptor 1 antagonist YM-230888 in chronic pain rodent models”. Eur. J. Pharmacol. 571 (1): 8—16. PMID 17597604. doi:10.1016/j.ejphar.2007.05.030.
Kohara, A.; T, Toya; Tamura, S.; et al. (2005). „Radioligand binding properties and pharmacological characterization of 6-amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamide (YM-298198), a high-affinity, selective, and noncompetitive antagonist of metabotropic glutamate receptor type 1”. J. Pharmacol. Exp. Ther. 315 (1): 163—9. PMID 15976016. doi:10.1124/jpet.105.087171.
Suzuki, G.; T, Kimura; Satow, A.; et al. (2007). „Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide (FTIDC)”. J. Pharmacol. Exp. Ther. 321 (3): 1144—53. PMID 17360958. doi:10.1124/jpet.106.116574.
El-Kouhen O; Lehto, S. G.; Pan, J. B.; et al. (2006). „Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist”. Br. J. Pharmacol. 149 (6): 761—74. PMC 2014656 . PMID 17016515. doi:10.1038/sj.bjp.0706877.
Vieira E, Huwyler J, Jolidon S, Knoflach F, Mutel V, Wichmann J (2009). „Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers”. Bioorg. Med. Chem. Lett. 19 (6): 1666—9. PMID 19233648. doi:10.1016/j.bmcl.2009.01.108.

wkhealth.com

meta.wkhealth.com

Makoff AJ, Phillips T, Pilling C, Emson P (1997). „Expression of a novel splice variant of human mGluR1 in the cerebellum”. Neuroreport. 8 (13): 2943—7. PMID 9376535. doi:10.1097/00001756-199709080-00027.