Khan Academy. Khan Academy(англ.). Процитовано 15 грудня 2017.
nih.gov
ncbi.nlm.nih.gov
The DNA damage response: making it safe to play with knives. Molecular Cell 40 (2): 179–204. October 2010. PMC 2988877. PMID 20965415. doi:10.1016/j.molcel.2010.09.019
DNA damage, aging, and cancer. The New England Journal of Medicine 361 (15): 1475–85. October 2009. PMID 19812404. doi:10.1056/NEJMra0804615
A review and appraisal of the DNA damage theory of ageing. Mutation Research 728 (1–2): 12–22. 2011. PMID 21600302. doi:10.1016/j.mrrev.2011.05.001
Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island. PLOS Genetics 4 (8): e1000155. August 2008. PMC 2491723. PMID 18704159. doi:10.1371/journal.pgen.1000155
Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):7915-22. doi: 10.1073/pnas.90.17.7915. PMID 8367443; PMCID: PMC47258
Helbock HJ, Beckman KB, Shigenaga MK, Walter PB, Woodall AA, Yeo HC, Ames BN (January 1998). "DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine". Proceedings of the National Academy of Sciences of the United States of America. 95 (1): 288–93. Bibcode:1998PNAS...95..288H. doi:10.1073/pnas.95.1.288. PMC 18204. PMID 9419368
Foksinski M, Rozalski R, Guz J, Ruszkowska B, Sztukowska P, Piwowarski M, et al. (November 2004). "Urinary excretion of DNA repair products correlates with metabolic rates as well as with maximum life spans of different mammalian species". Free Radical Biology & Medicine. 37 (9): 1449–54. doi:10.1016/j.freeradbiomed.2004.07.014. PMID 15454284
Tudek B, Winczura A, Janik J, Siomek A, Foksinski M, Oliński R (May 2010). "Involvement of oxidatively damaged DNA and repair in cancer development and aging". American Journal of Translational Research. 2 (3): 254–84. PMC 2892402. PMID 20589166
Helbock HJ, Beckman KB, Shigenaga MK, Walter PB, Woodall AA, Yeo HC, Ames BN (January 1998). "DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine". Proceedings of the National Academy of Sciences of the United States of America. 95 (1): 288–93. Bibcode:1998PNAS...95..288H. doi:10.1073/pnas.95.1.288. PMC 18204. PMID 9419368
Fraga CG, Shigenaga MK, Park JW, Degan P, Ames BN (June 1990). "Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine". Proceedings of the National Academy of Sciences of the United States of America. 87 (12): 4533–7. Bibcode:1990PNAS...87.4533F. doi:10.1073/pnas.87.12.4533. PMC 54150. PMID 2352934
Foksinski M, Rozalski R, Guz J, Ruszkowska B, Sztukowska P, Piwowarski M, et al. (November 2004). "Urinary excretion of DNA repair products correlates with metabolic rates as well as with maximum life spans of different mammalian species". Free Radical Biology & Medicine. 37 (9): 1449–54. doi:10.1016/j.freeradbiomed.2004.07.014. PMID 15454284
Hamilton ML, Guo Z, Fuller CD, Van Remmen H, Ward WF, Austad SN, et al. (May 2001). "A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA". Nucleic Acids Research. 29 (10): 2117–26. doi:10.1093/nar/29.10.2117. PMC 55450. PMID 11353081
Lindahl T, Nyberg B (September 1972). "Rate of depurination of native deoxyribonucleic acid". Biochemistry. 11 (19): 3610–8. doi:10.1021/bi00769a018. PMID 4626532
Lindahl T (April 1993). "Instability and decay of the primary structure of DNA". Nature. 362 (6422): 709–15. Bibcode:1993Natur.362..709L. doi:10.1038/362709a0. PMID 8469282. S2CID 4283694
Nakamura J, Walker VE, Upton PB, Chiang SY, Kow YW, Swenberg JA (January 1998). "Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions". Cancer Research. 58 (2): 222–5. PMID 9443396
Haber JE (July 1999). "DNA recombination: the replication connection". Trends in Biochemical Sciences. 24 (7): 271–5. doi:10.1016/s0968-0004(99)01413-9. PMID 10390616
Haber JE (July 1999). "DNA recombination: the replication connection". Trends in Biochemical Sciences. 24 (7): 271–5. doi:10.1016/s0968-0004(99)01413-9. PMID 10390616
Vilenchik MM, Knudson AG (October 2003). "Endogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancer". Proceedings of the National Academy of Sciences of the United States of America. 100 (22): 12871–6. Bibcode:2003PNAS..10012871V. doi:10.1073/pnas.2135498100. PMC 240711. PMID 14566050
Chan SW, Dedon PC (December 2010). "The biological and metabolic fates of endogenous DNA damage products". Journal of Nucleic Acids. 2010: 929047. doi:10.4061/2010/929047. PMC 3010698. PMID 21209721
Kadlubar FF, Anderson KE, Häussermann S, Lang NP, Barone GW, Thompson PA, et al. (September 1998). "Comparison of DNA adduct levels associated with oxidative stress in human pancreas". Mutation Research. 405 (2): 125–33. doi:10.1016/s0027-5107(98)00129-8. PMID 9748537
VanderVeen LA, Hashim MF, Shyr Y, Marnett LJ (November 2003). "Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogenous carcinogen malondialdehyde". Proceedings of the National Academy of Sciences of the United States of America. 100 (24): 14247–52. Bibcode:2003PNAS..10014247V. doi:10.1073/pnas.2332176100. PMC 283577. PMID 14603032
Tan X, Grollman AP, Shibutani S (December 1999). "Comparison of the mutagenic properties of 8-oxo-7,8-dihydro-2'-deoxyadenosine and 8-oxo-7,8-dihydro-2'-deoxyguanosine DNA lesions in mammalian cells". Carcinogenesis. 20 (12): 2287–92. doi:10.1093/carcin/20.12.2287. PMID 10590221
Hamilton ML, Guo Z, Fuller CD, Van Remmen H, Ward WF, Austad SN, et al. (May 2001). "A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA". Nucleic Acids Research. 29 (10): 2117–26. doi:10.1093/nar/29.10.2117. PMC 55450. PMID 11353081
Swenberg JA, Lu K, Moeller BC, Gao L, Upton PB, Nakamura J, Starr TB (March 2011). "Endogenous versus exogenous DNA adducts: their role in carcinogenesis, epidemiology, and risk assessment". Toxicological Sciences. 120 Suppl 1 (Suppl 1): S130-45. doi:10.1093/toxsci/kfq371. PMC 3043087. PMID 21163908
Nakamura J, Swenberg JA (June 1999). "Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues". Cancer Research. 59 (11): 2522–6. PMID 10363965
Xia J, Chiu LY, Nehring RB, Bravo Núñez MA, Mei Q, Perez M, et al. (January 2019). "Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage". Cell. 176 (1–2): 127–143.e24. doi:10.1016/j.cell.2018.12.008. PMC 6344048. PMID 30633903
PARP Inhibitors: The Cornerstone of DNA Repair-Targeted Therapies. Oncology 31 (4): 265–73. April 2017. PMID 28412778
Nucleotide excision repair in eukaryotes. Cold Spring Harbor Perspectives in Biology 5 (10): a012609. October 2013. PMC 3783044. PMID 24086042. doi:10.1101/cshperspect.a012609
Nucleotide excision repair and human syndromes. Carcinogenesis 21 (3): 453–60. March 2000. PMID 10688865. doi:10.1093/carcin/21.3.453
DNA excision-repair defect of xeroderma pigmentosum prevents removal of a class of oxygen free radical-induced base lesions. Proceedings of the National Academy of Sciences of the United States of America 90 (13): 6335–9. July 1993. Bibcode:1993PNAS...90.6335S. PMC 46923. PMID 8327515. doi:10.1073/pnas.90.13.6335
Repair Pathway Choices and Consequences at the Double-Strand Break. Trends in Cell Biology 26 (1): 52–64. January 2016. PMC 4862604. PMID 26437586. doi:10.1016/j.tcb.2015.07.009
DNA mismatch repair. Annual Review of Biochemistry 74: 681–710. 2005. PMID 15952900. doi:10.1146/annurev.biochem.74.082803.133243
DNA repair by reversal of DNA damage. Cold Spring Harbor Perspectives in Biology 5 (1): a012575. January 2013. PMC 3579392. PMID 23284047. doi:10.1101/cshperspect.a012575
Replication of damaged DNA by translesion synthesis in human cells. FEBS Letters 579 (4): 873–6. February 2005. PMID 15680966. doi:10.1016/j.febslet.2004.11.029
Deng T, Lyon CJ, Bergin S, Caligiuri MA, Hsueh WA (May 2016). "Obesity, Inflammation, and Cancer". Annual Review of Pathology. 11: 421–49. doi:10.1146/annurev-pathol-012615-044359. PMID 27193454
Jump up to:a b Iyengar NM, Gucalp A, Dannenberg AJ, Hudis CA (December 2016). "Obesity and Cancer Mechanisms: Tumor Microenvironment and÷ Inflammation". Journal of Clinical Oncology. 34 (35): 4270–4276. doi:10.1200/JCO.2016.67.4283. PMC 5562428. PMID 27903155
Ramos-Nino ME (2013). "The role of chronic inflammation in obesity-associated cancers". ISRN Oncology. 2013: 697521. doi:10.1155/2013/697521. PMC 3683483. PMID 23819063
Bernstein C, Holubec H, Bhattacharyya AK, Nguyen H, Payne CM, Zaitlin B, Bernstein H (August 2011). "Carcinogenicity of deoxycholate, a secondary bile acid". Archives of Toxicology. 85 (8): 863–71. doi:10.1007/s00204-011-0648-7. PMC 3149672. PMID 21267546
Zhang L, Yu J (December 2013). "Role of apoptosis in colon cancer biology, therapy, and prevention". Current Colorectal Cancer Reports. 9 (4): 331–340. doi:10.1007/s11888-013-0188-z. PMC 3836193. PMID 24273467
Williams GT, Critchlow MR, Hedge VL, O'Hare KB (December 1998). "Molecular failure of apoptosis: inappropriate cell survival and mutagenesis?". Toxicology Letters. 102–103: 485–9. doi:10.1016/s0378-4274(98)00343-9. PMID 10022300
Bernstein C, Bernstein H, Payne CM, Garewal H (June 2002). "DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis". Mutation Research. 511 (2): 145–78. doi:10.1016/s1383-5742(02)00009-1. PMID 12052432
Wang R, Hao W, Pan L, Boldogh I, Ba X (October 2018). "The roles of base excision repair enzyme OGG1 in gene expression". Cellular and Molecular Life Sciences. 75 (20): 3741–3750. doi:10.1007/s00018-018-2887-8. PMC 6154017. PMID 30043138
Seifermann M, Epe B (June 2017). "Oxidatively generated base modifications in DNA: Not only carcinogenic risk factor but also regulatory mark?". Free Radical Biology & Medicine. 107: 258–265. doi:10.1016/j.freeradbiomed.2016.11.018. PMID 27871818
Fleming AM, Burrows CJ (August 2017). "8-Oxo-7,8-dihydroguanine, friend and foe: Epigenetic-like regulator versus initiator of mutagenesis". DNA Repair. 56: 75–83. doi:10.1016/j.dnarep.2017.06.009. PMC 5548303. PMID 28629775
