Analysis of information sources in references of the Wikipedia article "Cyproterone acetate" in Vietnamese language version.
It is almost exclusively bound to plasma albumin.
The terminal half-life is about 38 h. A portion of the drug is metabolized by hydrolysis to cyproterone and acetic acid. However, in contrast to many other steroid esters hydrolysis is not extensive, and much of the pharmacological activity is exerted by the acetate form. Excretion is about 70% in the feces, mainly in the form of glucuronidated metabolites, and about 30% in the urine, predominantly as non-conjugated metabolites.
CPA is 100% bioavailable when taken orally with a half life of 38 hours. The injectable form reaches maximum plasma levels in 82 hours and has a half life of about 72 hours.
Since there is no binding of CPA to SHBG and CBG in the serum, 93% of the compound is bound to serum albumin.[liên kết hỏng]
Since there is no binding of CPA to SHBG and CBG in the serum, 93% of the compound is bound to serum albumin.[liên kết hỏng]
Since there is no binding of CPA to SHBG and CBG in the serum, 93% of the compound is bound to serum albumin.[liên kết hỏng]
