Analysis of information sources in references of the Wikipedia article "Natri floroacetat" in Vietnamese language version.
Sodium monofluoroacetate was readily absorbed and rapidly eliminated in all species: only traces were detectable in sheep muscle after 72-96 h
Glycerol monoacetate, 0.1 to 0.5 mL/kg/h, as a Krebs cycle substrate replacement, has prolonged survival in a primate model, but it also may aggravate toxicity and seems to be effective only early in the course.
General supportive measures are paramount and aimed at maintaining the airway, breathing, and circulation. Activated charcoal should be administered in all suspected ingestions presenting within 1 to 2 hours after ingestion. Seizures should be treated with benzodiazepines or barbiturates. Hypocalcemia and prolonged QTc intervals may require calcium and magnesium supplementation. Various treatments have been tested in animals [149,161-163]. The most useful agent appears to be glyceryl monoacetate, which provides excess acetate as a substrate for the TCA cycle. The clinical use of glyceryl monoacetate remains unproven, however.
So it was not humaneness that convinced PARC that Compound 1080 was the ideal tool for coyote control. Sodium monofluoroacetate had other attractions. It was cheap, and tiny amounts were effective: all you needed was sixteen grams, costing twenty-eight cents, to treat 1000 pounds of horsemeat, or enough, theoretically, to kill 11,428 coyotes at 1.4 ounces of bait meat per lethal dose.
Sodium monofluoroacetate was readily absorbed and rapidly eliminated in all species: only traces were detectable in sheep muscle after 72-96 h
Sodium fluoroacetate is an acute toxicant predacide which is used against coyotes which prey on sheep and goats.... Sodium fluoroacetate is a restricted use pesticide which may be used only by trained, certified applicators and which is only registered for use in livestock protection collars. Sodium fluoroacetate will retain the restricted use classification imposed by the Agency in 1978 due to its high acute toxicity and the need for highly specialized applicator training.... Development and use of sodium fluoroacetate as a predacide and rodenticide in the U.S. began in the 1940s prior to the 1947 enactment of the Federal Insecticide, Fungicide, and Rodenticide Act by which requirements for federal registration of pesticide products were instituted. In 1964 and again in 1971, the use of poisons to control predatory mammals were reviewed by selected committees. In 1972, EPA cancelled all registered predator control uses of sodium fluoroacetate, sodium cyanide, and strychnine. In 1977, the US Department of the Interior (USDI) applied for an Experimental Use Permit (EUP) to investigate the potential risks and benefits associated with the use of sodium fluoroacetate in "toxic collars" which would be placed on the necks of sheep and goats.... In 1981, EPA was petitioned by the USDI and livestock interests to revisit the 1972 predacide cancellation decision with respect to sodium fluoroacetate.... In 1985, EPA granted a registration to USDI for a toxic collar product which was transferred in 1986 to the Animal and Plant Health Inspection Service (APHIS) of the US Department of Agriculture (USDA).... The rodenticide uses of sodium fluoroacetate were cancelled due to lack of supporting data. In 1989, all "special local needs" registrations issued under § 24(c) of FIFRA were cancelled, and all pending applications for Federal registration were denied by August 1990.
Coyotes are the leading cause of predation losses for sheep and goat producers.... The LPC is registered by the Environmental Protection Agency (EPA) as a restricted use product.
Coyotes are the leading cause of predation losses for sheep and goat producers.... The LPC is registered by the Environmental Protection Agency (EPA) as a restricted use product.
Sodium monofluoroacetate was readily absorbed and rapidly eliminated in all species: only traces were detectable in sheep muscle after 72-96 h
