The reaction was first observed 1833: Ferdinand Rose (1833) "Über die Verbindungen des Eiweiss mit Metalloxyden" (On the compounds of albumin with metal oxides), Poggendorfs Annalen der Physik und Chemie, vol. 104, pages 132-142, doi:10.1002/andp.18331040512. It was independently rediscovered in 1857 by a Polish physiologist: G. Piotrowski (1857) "Eine neue Reaction auf Eiweisskörper und ihre näheren Abkömmlinge" (A new reaction of proteins and their related derivatives) Sitzungsberichte der Kaiserliche Akademie der Wissenschaften in Wien, mathematisch-naturwissenschaftliche Classe (Proceedings of the Imperial Academy of Philosophies in Vienna, mathematical-natural sciences section), vol. 24, pages 335-337.
doi.org
Datta, S. P.; Leberman, R.; Rabin, B. R. (1959). “The chelation of metal ions by dipeptides and related substances. Part 5.—Cupric complexes of sarcosyl and leucyl ligands”. Trans. Faraday Soc. Royal Society of Chemistry (RSC). 55 (0): 2141–2151. doi:10.1039/tf9595502141. ISSN0014-7672.
Datta, S. P.; Leberman, R.; Rabin, B. R. (1959). “The chelation of metal ions by dipeptides and related substances. Part 5.—Cupric complexes of sarcosyl and leucyl ligands”. Trans. Faraday Soc. Royal Society of Chemistry (RSC). 55 (0): 2141–2151. doi:10.1039/tf9595502141. ISSN0014-7672.
