(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices. European Journal of Pharmacology. August 2000, 401 (2): 145–53. PMID 10924919. doi:10.1016/S0014-2999(00)00433-7.
Effects of S 18986-1, a novel cognitive enhancer, on memory performances in an object recognition task in rats. European Journal of Pharmacology. August 2000, 401 (2): 205–12. PMID 10924928. doi:10.1016/S0014-2999(00)00429-5.
Positive allosteric modulators of AMPA receptors are neuroprotective against lesions induced by an NMDA agonist in neonatal mouse brain. Brain Research. April 2003, 970 (1–2): 221–5. PMID 12706264. doi:10.1016/S0006-8993(03)02357-6.
S 18986, a positive modulator of AMPA receptors with cognition-enhancing properties, increases ACh release in the hippocampus of young and aged rat. Neuroscience Letters. May 2004, 361 (1–3): 120–3. PMID 15135908. doi:10.1016/j.neulet.2003.12.061.
Neuropharmacokinetics of a new alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) modulator, S18986 [(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide], in the rat. Drug Metabolism and Disposition. August 2005, 33 (8): 1137–43. PMID 15860654. doi:10.1124/dmd.105.004424.
The AMPA modulator S 18986 improves declarative and working memory performances in aged mice. Behavioural Pharmacology. May 2008, 19 (3): 235–44. PMID 18469541. doi:10.1097/FBP.0b013e3282feb0c1.
Effects of the AMPA receptor modulator S 18986 on measures of cognition and oxidative stress in aged rats. Psychopharmacology. January 2009, 202 (1–3): 225–35. PMID 18762915. doi:10.1007/s00213-008-1301-x.
GAP-43 is essential for the neurotrophic effects of BDNF and positive AMPA receptor modulator S18986. Cell Death and Differentiation. April 2009, 16 (4): 624–37. PMID 19136940. doi:10.1038/cdd.2008.188.
The AMPA receptor positive allosteric modulator, S18986, is neuroprotective against neonatal excitotoxic and inflammatory brain damage through BDNF synthesis. Neuropharmacology. September 2009, 57 (3): 277–86. PMID 19501111. doi:10.1016/j.neuropharm.2009.05.010.
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(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices. European Journal of Pharmacology. August 2000, 401 (2): 145–53. PMID 10924919. doi:10.1016/S0014-2999(00)00433-7.
Effects of S 18986-1, a novel cognitive enhancer, on memory performances in an object recognition task in rats. European Journal of Pharmacology. August 2000, 401 (2): 205–12. PMID 10924928. doi:10.1016/S0014-2999(00)00429-5.
Positive allosteric modulators of AMPA receptors are neuroprotective against lesions induced by an NMDA agonist in neonatal mouse brain. Brain Research. April 2003, 970 (1–2): 221–5. PMID 12706264. doi:10.1016/S0006-8993(03)02357-6.
S 18986, a positive modulator of AMPA receptors with cognition-enhancing properties, increases ACh release in the hippocampus of young and aged rat. Neuroscience Letters. May 2004, 361 (1–3): 120–3. PMID 15135908. doi:10.1016/j.neulet.2003.12.061.
Neuropharmacokinetics of a new alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) modulator, S18986 [(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide], in the rat. Drug Metabolism and Disposition. August 2005, 33 (8): 1137–43. PMID 15860654. doi:10.1124/dmd.105.004424.
The AMPA modulator S 18986 improves declarative and working memory performances in aged mice. Behavioural Pharmacology. May 2008, 19 (3): 235–44. PMID 18469541. doi:10.1097/FBP.0b013e3282feb0c1.
Effects of the AMPA receptor modulator S 18986 on measures of cognition and oxidative stress in aged rats. Psychopharmacology. January 2009, 202 (1–3): 225–35. PMID 18762915. doi:10.1007/s00213-008-1301-x.
GAP-43 is essential for the neurotrophic effects of BDNF and positive AMPA receptor modulator S18986. Cell Death and Differentiation. April 2009, 16 (4): 624–37. PMID 19136940. doi:10.1038/cdd.2008.188.
The AMPA receptor positive allosteric modulator, S18986, is neuroprotective against neonatal excitotoxic and inflammatory brain damage through BDNF synthesis. Neuropharmacology. September 2009, 57 (3): 277–86. PMID 19501111. doi:10.1016/j.neuropharm.2009.05.010.