厄洛替尼 (Chinese Wikipedia)

Gijtenbeek RG, van der Noort V, Aerts JG, Staal-van den Brekel JA, Smit EF, Krouwels FH, Wilschut FA, Hiltermann TJ, Timens W, Schuuring E, Janssen JD, Goosens M, van den Berg PM, de Langen AJ, Stigt JA, van den Borne BE, Groen HJ, van Geffen WH, van der Wekken AJ. Randomised controlled trial of first-line tyrosine-kinase inhibitor (TKI) versus intercalated TKI with chemotherapy for EGFR-mutated nonsmall cell lung cancer. ERJ Open Research. October 2022, 8 (4): 00239–2022. PMC 9574558 . PMID 36267895. doi:10.1183/23120541.00239-2022.
Cohen MH, Johnson JR, Chen YF, Sridhara R, Pazdur R. FDA drug approval summary: erlotinib (Tarceva) tablets. The Oncologist. August 2005, 10 (7): 461–466. PMID 16079312. S2CID 10218263. doi:10.1634/theoncologist.10-7-461 .
Kobayashi K, Hagiwara K. Epidermal growth factor receptor (EGFR) mutation and personalized therapy in advanced nonsmall cell lung cancer (NSCLC). Targeted Oncology. March 2013, 8 (1): 27–33. PMC 3591525 . PMID 23361373. doi:10.1007/s11523-013-0258-9.
Qi WX, Shen Z, Lin F, Sun YJ, Min DL, Tang LN, He AN, Yao Y. Comparison of the efficacy and safety of EFGR tyrosine kinase inhibitor monotherapy with standard second-line chemotherapy in previously treated advanced non-small-cell lung cancer: a systematic review and meta-analysis. Asian Pacific Journal of Cancer Prevention. 2012, 13 (10): 5177–5182. PMID 23244131. doi:10.7314/APJCP.2012.13.10.5177 .
Balak MN, Gong Y, Riely GJ, Somwar R, Li AR, Zakowski MF, Chiang A, Yang G, Ouerfelli O, Kris MG, Ladanyi M, Miller VA, Pao W. Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors. Clinical Cancer Research. November 2006, 12 (21): 6494–6501. PMID 17085664. doi:10.1158/1078-0432.CCR-06-1570 .
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, Lindeman N, Gale CM, Zhao X, Christensen J, Kosaka T, Holmes AJ, Rogers AM, Cappuzzo F, Mok T, Lee C, Johnson BE, Cantley LC, Jänne PA. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science. May 2007, 316 (5827): 1039–1043. Bibcode:2007Sci...316.1039E. PMID 17463250. S2CID 23254145. doi:10.1126/science.1141478 .
Bean J, Brennan C, Shih JY, Riely G, Viale A, Wang L, Chitale D, Motoi N, Szoke J, Broderick S, Balak M, Chang WC, Yu CJ, Gazdar A, Pass H, Rusch V, Gerald W, Huang SF, Yang PC, Miller V, Ladanyi M, Yang CH, Pao W. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proceedings of the National Academy of Sciences of the United States of America. December 2007, 104 (52): 20932–20937. Bibcode:2007PNAS..10420932B. PMC 2409244 . PMID 18093943. doi:10.1073/pnas.0710370104 .
Dudek AZ, Kmak KL, Koopmeiners J, Keshtgarpour M. Skin rash and bronchoalveolar histology correlates with clinical benefit in patients treated with gefitinib as a therapy for previously treated advanced or metastatic non-small cell lung cancer. Lung Cancer. January 2006, 51 (1): 89–96. PMID 16290256. doi:10.1016/j.lungcan.2005.09.002.
Pérez-Soler R, Chachoua A, Hammond LA, Rowinsky EK, Huberman M, Karp D, Rigas J, Clark GM, Santabárbara P, Bonomi P. Determinants of tumor response and survival with erlotinib in patients with non--small-cell lung cancer. Journal of Clinical Oncology. August 2004, 22 (16): 3238–3247. PMID 15310767. doi:10.1200/JCO.2004.11.057 .
Li X, Kamenecka TM, Cameron MD. Cytochrome P450-mediated bioactivation of the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophile. Drug Metabolism and Disposition. July 2010, 38 (7): 1238–1245. PMC 3202369 . PMID 20382753. doi:10.1124/dmd.109.030361.
Ren S, Li Y, Li W, Zhao Z, Jin C, Zhang D. Fatal asymmetric interstitial lung disease after erlotinib for lung cancer. Respiration; International Review of Thoracic Diseases. 2012, 84 (5): 431–435. PMID 22889962. doi:10.1159/000339508 .
Khurana V, Minocha M, Pal D, Mitra AK. Role of OATP-1B1 and/or OATP-1B3 in hepatic disposition of tyrosine kinase inhibitors. Drug Metabolism and Drug Interactions. March 2014, 29 (3): 179–190. PMC 4407685 . PMID 24643910. doi:10.1515/dmdi-2013-0062.
Khurana V, Minocha M, Pal D, Mitra AK. Inhibition of OATP-1B1 and OATP-1B3 by tyrosine kinase inhibitors. Drug Metabolism and Drug Interactions. May 2014, 29 (4): 249–259. PMC 4407688 . PMID 24807167. doi:10.1515/dmdi-2014-0014.
Raymond E, Faivre S, Armand JP. Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy. Drugs. 2000, 60 (Suppl 1): 15–23; discussion 41–2. PMID 11129168. S2CID 10555942. doi:10.2165/00003495-200060001-00002 .
Adis International Ltd. Erlotinib: CP 358774, NSC 718781, OSI 774, R 1415. Drugs in R&D. 2003, 4 (4): 243–248. PMID 12848590. doi:10.2165/00126839-200304040-00006.

drugpatentwatch.com

Erlotinib - Generic Drug Details. DrugPatentWatch.com. （原始内容存档于2016-04-28）.

drugs.com

Erlotinib (Tarceva) Use During Pregnancy. Drugs.com. 2019-11-01 [2019-12-23]. （原始内容存档于12 November 2019）.
Erlotinib Monograph for Professionals. Drugs.com. [2019-11-12]. （原始内容存档于2019-12-24）.
Generic Tarceva Availability. Drugs.com. 2024-09-11 [2024-09-24].

fda.gov

accessdata.fda.gov

Drug Approval Package: Tarceva (Erlotinib) NDA #021743. U.S. Food and Drug Administration (FDA). 2005-03-28 [2019-12-23]. （原始内容存档于2019-12-23）.

genomeweb.com

FDA Approves Roche Test as CDx for Tarceva for Treating Certain NSCLC Patients. GenomeWeb. 2013-05-15 [2020-01-10]. （原始内容存档于2019-09-06）（美国英语）.

guildlink.com.au

Tarceva (Erlotinib hydrochloride). Roche Products Pty Limited. Australian Product Information. 2022-08-31.

handle.net

hdl.handle.net

Organization, World Health. World Health Organization model list of essential medicines: 21st list 2019. World Health Organization. 2019. hdl:10665/325771.

harvard.edu

ui.adsabs.harvard.edu

Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, Lindeman N, Gale CM, Zhao X, Christensen J, Kosaka T, Holmes AJ, Rogers AM, Cappuzzo F, Mok T, Lee C, Johnson BE, Cantley LC, Jänne PA. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science. May 2007, 316 (5827): 1039–1043. Bibcode:2007Sci...316.1039E. PMID 17463250. S2CID 23254145. doi:10.1126/science.1141478 .
Bean J, Brennan C, Shih JY, Riely G, Viale A, Wang L, Chitale D, Motoi N, Szoke J, Broderick S, Balak M, Chang WC, Yu CJ, Gazdar A, Pass H, Rusch V, Gerald W, Huang SF, Yang PC, Miller V, Ladanyi M, Yang CH, Pao W. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proceedings of the National Academy of Sciences of the United States of America. December 2007, 104 (52): 20932–20937. Bibcode:2007PNAS..10420932B. PMC 2409244 . PMID 18093943. doi:10.1073/pnas.0710370104 .

invntree.com

The end of Roche vs. Cipla infringement lawsuit. invntree. [2024-09-24].

lexology.com

Roche Vs Cipla: Final leg of battle over Tarceva Patent. RNA Technology and IP Attorneys. 2016-02-02 [2024-09-24].

nih.gov

ncbi.nlm.nih.gov

Gijtenbeek RG, van der Noort V, Aerts JG, Staal-van den Brekel JA, Smit EF, Krouwels FH, Wilschut FA, Hiltermann TJ, Timens W, Schuuring E, Janssen JD, Goosens M, van den Berg PM, de Langen AJ, Stigt JA, van den Borne BE, Groen HJ, van Geffen WH, van der Wekken AJ. Randomised controlled trial of first-line tyrosine-kinase inhibitor (TKI) versus intercalated TKI with chemotherapy for EGFR-mutated nonsmall cell lung cancer. ERJ Open Research. October 2022, 8 (4): 00239–2022. PMC 9574558 . PMID 36267895. doi:10.1183/23120541.00239-2022.
Cohen MH, Johnson JR, Chen YF, Sridhara R, Pazdur R. FDA drug approval summary: erlotinib (Tarceva) tablets. The Oncologist. August 2005, 10 (7): 461–466. PMID 16079312. S2CID 10218263. doi:10.1634/theoncologist.10-7-461 .
Kobayashi K, Hagiwara K. Epidermal growth factor receptor (EGFR) mutation and personalized therapy in advanced nonsmall cell lung cancer (NSCLC). Targeted Oncology. March 2013, 8 (1): 27–33. PMC 3591525 . PMID 23361373. doi:10.1007/s11523-013-0258-9.
Qi WX, Shen Z, Lin F, Sun YJ, Min DL, Tang LN, He AN, Yao Y. Comparison of the efficacy and safety of EFGR tyrosine kinase inhibitor monotherapy with standard second-line chemotherapy in previously treated advanced non-small-cell lung cancer: a systematic review and meta-analysis. Asian Pacific Journal of Cancer Prevention. 2012, 13 (10): 5177–5182. PMID 23244131. doi:10.7314/APJCP.2012.13.10.5177 .
Balak MN, Gong Y, Riely GJ, Somwar R, Li AR, Zakowski MF, Chiang A, Yang G, Ouerfelli O, Kris MG, Ladanyi M, Miller VA, Pao W. Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors. Clinical Cancer Research. November 2006, 12 (21): 6494–6501. PMID 17085664. doi:10.1158/1078-0432.CCR-06-1570 .
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, Lindeman N, Gale CM, Zhao X, Christensen J, Kosaka T, Holmes AJ, Rogers AM, Cappuzzo F, Mok T, Lee C, Johnson BE, Cantley LC, Jänne PA. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science. May 2007, 316 (5827): 1039–1043. Bibcode:2007Sci...316.1039E. PMID 17463250. S2CID 23254145. doi:10.1126/science.1141478 .
Bean J, Brennan C, Shih JY, Riely G, Viale A, Wang L, Chitale D, Motoi N, Szoke J, Broderick S, Balak M, Chang WC, Yu CJ, Gazdar A, Pass H, Rusch V, Gerald W, Huang SF, Yang PC, Miller V, Ladanyi M, Yang CH, Pao W. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proceedings of the National Academy of Sciences of the United States of America. December 2007, 104 (52): 20932–20937. Bibcode:2007PNAS..10420932B. PMC 2409244 . PMID 18093943. doi:10.1073/pnas.0710370104 .
Dudek AZ, Kmak KL, Koopmeiners J, Keshtgarpour M. Skin rash and bronchoalveolar histology correlates with clinical benefit in patients treated with gefitinib as a therapy for previously treated advanced or metastatic non-small cell lung cancer. Lung Cancer. January 2006, 51 (1): 89–96. PMID 16290256. doi:10.1016/j.lungcan.2005.09.002.
Pérez-Soler R, Chachoua A, Hammond LA, Rowinsky EK, Huberman M, Karp D, Rigas J, Clark GM, Santabárbara P, Bonomi P. Determinants of tumor response and survival with erlotinib in patients with non--small-cell lung cancer. Journal of Clinical Oncology. August 2004, 22 (16): 3238–3247. PMID 15310767. doi:10.1200/JCO.2004.11.057 .
Li X, Kamenecka TM, Cameron MD. Cytochrome P450-mediated bioactivation of the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophile. Drug Metabolism and Disposition. July 2010, 38 (7): 1238–1245. PMC 3202369 . PMID 20382753. doi:10.1124/dmd.109.030361.
Ren S, Li Y, Li W, Zhao Z, Jin C, Zhang D. Fatal asymmetric interstitial lung disease after erlotinib for lung cancer. Respiration; International Review of Thoracic Diseases. 2012, 84 (5): 431–435. PMID 22889962. doi:10.1159/000339508 .
Khurana V, Minocha M, Pal D, Mitra AK. Role of OATP-1B1 and/or OATP-1B3 in hepatic disposition of tyrosine kinase inhibitors. Drug Metabolism and Drug Interactions. March 2014, 29 (3): 179–190. PMC 4407685 . PMID 24643910. doi:10.1515/dmdi-2013-0062.
Khurana V, Minocha M, Pal D, Mitra AK. Inhibition of OATP-1B1 and OATP-1B3 by tyrosine kinase inhibitors. Drug Metabolism and Drug Interactions. May 2014, 29 (4): 249–259. PMC 4407688 . PMID 24807167. doi:10.1515/dmdi-2014-0014.
Raymond E, Faivre S, Armand JP. Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy. Drugs. 2000, 60 (Suppl 1): 15–23; discussion 41–2. PMID 11129168. S2CID 10555942. doi:10.2165/00003495-200060001-00002 .
Adis International Ltd. Erlotinib: CP 358774, NSC 718781, OSI 774, R 1415. Drugs in R&D. 2003, 4 (4): 243–248. PMID 12848590. doi:10.2165/00126839-200304040-00006.

dailymed.nlm.nih.gov

Tarceva- erlotinib hydrochloride tablet. DailyMed. 2018-12-12 [2019-12-23]. （原始内容存档于2020-08-06）.

roche.com

Roche obtains license for EGFR lung cancer assays and will develop Tarceva companion diagnostic test. Roche (新闻稿). [2020-01-10]. （原始内容存档于2022-02-24）.

semanticscholar.org

api.semanticscholar.org

Cohen MH, Johnson JR, Chen YF, Sridhara R, Pazdur R. FDA drug approval summary: erlotinib (Tarceva) tablets. The Oncologist. August 2005, 10 (7): 461–466. PMID 16079312. S2CID 10218263. doi:10.1634/theoncologist.10-7-461 .
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, Lindeman N, Gale CM, Zhao X, Christensen J, Kosaka T, Holmes AJ, Rogers AM, Cappuzzo F, Mok T, Lee C, Johnson BE, Cantley LC, Jänne PA. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science. May 2007, 316 (5827): 1039–1043. Bibcode:2007Sci...316.1039E. PMID 17463250. S2CID 23254145. doi:10.1126/science.1141478 .
Raymond E, Faivre S, Armand JP. Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy. Drugs. 2000, 60 (Suppl 1): 15–23; discussion 41–2. PMID 11129168. S2CID 10555942. doi:10.2165/00003495-200060001-00002 .

spicyip.com

Roche v. Cipla- The Sense of An Ending. SpicyIP. [2024-09-24].

tarceva.com

April 2010 - Tarceva Indication Announcement Letter (PDF). [2010-12-18]. （原始内容存档 (PDF)于2011-07-16）.

web.archive.org

Erlotinib (Tarceva) Use During Pregnancy. Drugs.com. 2019-11-01 [2019-12-23]. （原始内容存档于12 November 2019）.
Tarceva- erlotinib hydrochloride tablet. DailyMed. 2018-12-12 [2019-12-23]. （原始内容存档于2020-08-06）.
Erlotinib Monograph for Professionals. Drugs.com. [2019-11-12]. （原始内容存档于2019-12-24）.
Drug Approval Package: Tarceva (Erlotinib) NDA #021743. U.S. Food and Drug Administration (FDA). 2005-03-28 [2019-12-23]. （原始内容存档于2019-12-23）.
2009 - SATURN: A double-blind, randomized, phase III study of maintenance erlotinib versus placebo following nonprogression with first-line platinum-based chemotherapy in patients with advanced NSCLC.. [18 December 2010]. （原始内容存档于2010-12-22）.
April 2010 - Tarceva Indication Announcement Letter (PDF). [2010-12-18]. （原始内容存档 (PDF)于2011-07-16）.
Roche obtains license for EGFR lung cancer assays and will develop Tarceva companion diagnostic test. Roche (新闻稿). [2020-01-10]. （原始内容存档于2022-02-24）.
Takimoto CH, Calvo E, Principles of Oncologic Pharmacotherapy, 2009-04-15 [2009-06-18], （原始内容存档于2009-05-15）
FDA Approves Roche Test as CDx for Tarceva for Treating Certain NSCLC Patients. GenomeWeb. 2013-05-15 [2020-01-10]. （原始内容存档于2019-09-06）（美国英语）.
Erlotinib - Generic Drug Details. DrugPatentWatch.com. （原始内容存档于2016-04-28）.