嵌合抗原受體T細胞 (Chinese Wikipedia)

Analysis of information sources in references of the Wikipedia article "嵌合抗原受體T細胞" in Chinese language version.

refsWebsite

Global rank Chinese rank

77doi.org

2^nd place

23^rd place

74nih.gov

4^th place

5^th place

16semanticscholar.org

11^th place

332^nd place

15web.archive.org

1^st place

13worldcat.org

5^th place

12^th place

6harvard.edu

18^th place

57^th place

2endocyte.com

low place

1cancer.gov

1,684^th place

696^th place

1nbcnews.com

137^th place

538^th place

1jstor.org

26^th place

113^th place

1fda.gov

447^th place

581^st place

1karger.com

4,489^th place

2,957^th place

1clinicaltrials.gov

5,225^th place

4,888^th place

1creativecommons.org

1,010^th place

2,830^th place

1labiotech.eu

low place

1nature.com

234^th place

227^th place

1cms.gov

low place

1hematology.org

low place

1susupport.com

low place

1gov.br

5,564^th place

low place

cancer.gov

chimeric antigen receptor T-cell therapy. National Cancer Institute.

clinicaltrials.gov

Study Evaluating the Efficacy and Safety of JCAR015 in Adult B-cell Acute Lymphoblastic Leukemia (B-ALL). ClinicalTrials.gov. [2018-02-21]. （原始内容存档于2023-04-05）.

cms.gov

Decision Memo for Chimeric Antigen Receptor (CAR) T-cell Therapy for Cancers (CAG-00451N). www.cms.gov. [2021-03-22]. （原始内容存档于2021-05-14）（美国英语）.

creativecommons.org

Chandran SS, Klebanoff CA. T cell receptor-based cancer immunotherapy: Emerging efficacy and pathways of resistance. Immunological Reviews. July 2019, 290 (1): 127–147. PMC 7027847 . PMID 31355495. doi:10.1111/imr.12772 . Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License （页面存档备份，存于互联网档案馆）.

doi.org

Srivastava S, Riddell SR. Engineering CAR-T cells: Design concepts. Trends in Immunology. August 2015, 36 (8): 494–502. PMC 4746114 . PMID 26169254. doi:10.1016/j.it.2015.06.004.
Hartmann J, Schüßler-Lenz M, Bondanza A, Buchholz CJ. Clinical development of CAR T cells-challenges and opportunities in translating innovative treatment concepts. EMBO Molecular Medicine. September 2017, 9 (9): 1183–1197. PMC 5582407 . PMID 28765140. doi:10.15252/emmm.201607485.
Tang XJ, Sun XY, Huang KM, Zhang L, Yang ZS, Zou DD, et al. Therapeutic potential of CAR-T cell-derived exosomes: a cell-free modality for targeted cancer therapy. Oncotarget. December 2015, 6 (42): 44179–44190. PMC 4792550 . PMID 26496034. doi:10.18632/oncotarget.6175.
Zhang H, Zhao P, Huang H. Engineering better chimeric antigen receptor T cells. Experimental Hematology & Oncology. December 2020, 9 (1): 34. PMC 7709221 . PMID 33292660. doi:10.1186/s40164-020-00190-2.
Bupha-Intr O, Haeusler G, Chee L, Thursky K, Slavin M, Teh B. CAR-T cell therapy and infection: a review. Expert Review of Anti-Infective Therapy. June 2021, 19 (6): 749–758. PMID 33249873. S2CID 227235627. doi:10.1080/14787210.2021.1855143.
Bonifant CL, Jackson HJ, Brentjens RJ, Curran KJ. Toxicity and management in CAR T-cell therapy. Molecular Therapy: Oncolytics. 2016, 3: 16011. PMC 5008265 . PMID 27626062. doi:10.1038/mto.2016.11.
Kuwana Y, Asakura Y, Utsunomiya N, Nakanishi M, Arata Y, Itoh S, et al. Expression of chimeric receptor composed of immunoglobulin-derived V regions and T-cell receptor-derived C regions. Biochemical and Biophysical Research Communications. December 1987, 149 (3): 960–968. PMID 3122749. doi:10.1016/0006-291x(87)90502-x.
Rosenbaum L. Tragedy, Perseverance, and Chance - The Story of CAR-T Therapy. The New England Journal of Medicine. October 2017, 377 (14): 1313–1315. PMID 28902570. doi:10.1056/NEJMp1711886.
Gross G, Waks T, Eshhar Z. Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity. Proceedings of the National Academy of Sciences of the United States of America. December 1989, 86 (24): 10024–10028. Bibcode:1989PNAS...8610024G. JSTOR 34790. PMC 298636 . PMID 2513569. doi:10.1073/pnas.86.24.10024 .
Eshhar Z, Bach N, Fitzer-Attas CJ, Gross G, Lustgarten J, Waks T, Schindler DG. The T-body approach: potential for cancer immunotherapy. Springer Seminars in Immunopathology. 1996, 18 (2): 199–209. PMID 8908700. S2CID 19872173. doi:10.1007/BF00820666.
Irving BA, Weiss A. The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways. Cell. March 1991, 64 (5): 891–901. PMID 1705867. S2CID 23466990. doi:10.1016/0092-8674(91)90314-o.
Hege KM, Roberts MR. T-cell gene therapy. Current Opinion in Biotechnology. December 1996, 7 (6): 629–634. PMID 8939644. doi:10.1016/s0958-1669(96)80074-7.
June CH, Sadelain M. Chimeric Antigen Receptor Therapy. The New England Journal of Medicine. July 2018, 379 (1): 64–73. PMC 7433347 . PMID 29972754. doi:10.1056/NEJMra1706169.
Braendstrup P, Levine BL, Ruella M. The long road to the first FDA-approved gene therapy: chimeric antigen receptor T cells targeting CD19. Cytotherapy. February 2020, 22 (2): 57–69. PMC 7036015 . PMID 32014447. doi:10.1016/j.jcyt.2019.12.004.
Sadelain M, Rivière I, Brentjens R. Targeting tumours with genetically enhanced T lymphocytes. Nature Reviews. Cancer. January 2003, 3 (1): 35–45. PMID 12509765. S2CID 33707802. doi:10.1038/nrc971.
Jin C, Yu D, Hillerdal V, Wallgren A, Karlsson-Parra A, Essand M. Allogeneic lymphocyte-licensed DCs expand T cells with improved antitumor activity and resistance to oxidative stress and immunosuppressive factors. Molecular Therapy: Methods & Clinical Development. 2014-03-05, 1: 14001. PMC 4362340 . PMID 26015949. doi:10.1038/mtm.2014.1.
Li, Nan; Ho, Mitchell. Development of Glypican-2 Targeting Single-Domain Antibody CAR T Cells for Neuroblastoma. Single-Domain Antibodies. Methods in Molecular Biology 2446. 2022: 451–468 [2023-10-11]. ISBN 978-1-0716-2074-8. ISSN 1940-6029. PMID 35157288. S2CID 246813053. doi:10.1007/978-1-0716-2075-5_23. （原始内容存档于2023-12-16）.
Makita S, Yoshimura K, Tobinai K. Clinical development of anti-CD19 chimeric antigen receptor T-cell therapy for B-cell non-Hodgkin lymphoma. Cancer Science. June 2017, 108 (6): 1109–1118. PMC 5480083 . PMID 28301076. doi:10.1111/cas.13239.
Jin C, Fotaki G, Ramachandran M, Nilsson B, Essand M, Yu D. Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer. EMBO Molecular Medicine. July 2016, 8 (7): 702–711. PMC 4931286 . PMID 27189167. doi:10.15252/emmm.201505869.
Jensen TI, Axelgaard E, Bak RO. Therapeutic gene editing in haematological disorders with CRISPR/Cas9. British Journal of Haematology. June 2019, 185 (5): 821–835. PMID 30864164. doi:10.1111/bjh.15851 .
Muranski P, Boni A, Wrzesinski C, Citrin DE, Rosenberg SA, Childs R, Restifo NP. Increased intensity lymphodepletion and adoptive immunotherapy--how far can we go?. Nature Clinical Practice. Oncology. December 2006, 3 (12): 668–681. PMC 1773008 . PMID 17139318. doi:10.1038/ncponc0666.
Xin Yu J, Hubbard-Lucey VM, Tang J. The global pipeline of cell therapies for cancer. Nature Reviews. Drug Discovery. October 2019, 18 (11): 821–822. PMID 31673124. S2CID 190862546. doi:10.1038/d41573-019-00090-z.
Almåsbak H, Aarvak T, Vemuri MC. CAR T Cell Therapy: A Game Changer in Cancer Treatment. Journal of Immunology Research. 2016, 2016: 5474602. PMC 4889848 . PMID 27298832. doi:10.1155/2016/5474602 .
Jacobson CA, Ritz J. Time to put the CAR-T before the horse. Blood. November 2011, 118 (18): 4761–4762. PMID 22053170. doi:10.1182/blood-2011-09-376137 .
Li, Nan; Spetz, Madeline R.; Li, Dan; Ho, Mitchell. Advances in immunotherapeutic targets for childhood cancers: A focus on glypican-2 and B7-H3. Pharmacology & Therapeutics. July 2021, 223: 107892. ISSN 1879-016X. PMC 8202769 . PMID 33992682. doi:10.1016/j.pharmthera.2021.107892.
Li, Dan; Lin, Shaoli; Hong, Jessica; Ho, Mitchell. Immunotherapy for hepatobiliary cancers: Emerging targets and translational advances. Advances in Cancer Research. 2022, 156: 415–449 [2023-10-19]. ISBN 9780323983921. ISSN 2162-5557. PMID 35961708. S2CID 246978004. doi:10.1016/bs.acr.2022.01.013. （原始内容存档于2023-12-16）.
Kochenderfer JN, Wilson WH, Janik JE, Dudley ME, Stetler-Stevenson M, Feldman SA, et al. Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19. Blood. November 2010, 116 (20): 4099–4102. PMC 2993617 . PMID 20668228. doi:10.1182/blood-2010-04-281931 .
Kochenderfer JN, Dudley ME, Kassim SH, Somerville RP, Carpenter RO, Stetler-Stevenson M, et al. Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor. Journal of Clinical Oncology. February 2015, 33 (6): 540–549. PMC 4322257 . PMID 25154820. doi:10.1200/JCO.2014.56.2025.
Schultz L, Mackall C. Driving CAR T cell translation forward. Science Translational Medicine. February 2019, 11 (481): eaaw2127. PMID 30814337. doi:10.1126/scitranslmed.aaw2127 .
Lim WA, June CH. The Principles of Engineering Immune Cells to Treat Cancer. Cell. February 2017, 168 (4): 724–740. PMC 5553442 . PMID 28187291. doi:10.1016/j.cell.2017.01.016.
Li D, Li N, Zhang YF, Fu H, Feng M, Schneider D, et al. Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice. Gastroenterology. June 2020, 158 (8): 2250–2265.e20. PMC 7282931 . PMID 32060001. doi:10.1053/j.gastro.2020.02.011.
Li, Nan; Fu, Haiying; Hewitt, Stephen M.; Dimitrov, Dimiter S.; Ho, Mitchell. Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America. 2017-08-08, 114 (32): E6623–E6631. Bibcode:2017PNAS..114E6623L. ISSN 1091-6490. PMC 5559039 . PMID 28739923. doi:10.1073/pnas.1706055114 .
Li, Nan; Torres, Madeline B.; Spetz, Madeline R.; Wang, Ruixue; Peng, Luyi; Tian, Meijie; Dower, Christopher M.; Nguyen, Rosa; Sun, Ming; Tai, Chin-Hsien; de Val, Natalia; Cachau, Raul; Wu, Xiaolin; Hewitt, Stephen M.; Kaplan, Rosandra N. CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice. Cell Reports. Medicine. 2021-06-15, 2 (6): 100297. ISSN 2666-3791. PMC 8233664 . PMID 34195677. doi:10.1016/j.xcrm.2021.100297.
Zhang Q, Lu W, Liang CL, Chen Y, Liu H, Qiu F, Dai Z. Chimeric Antigen Receptor (CAR) Treg: A Promising Approach to Inducing Immunological Tolerance. Frontiers in Immunology. 2018, 9: 2359. PMC 6194362 . PMID 30369931. doi:10.3389/fimmu.2018.02359 .
Mougiakakos D, Krönke G, Völkl S, Kretschmann S, Aigner M, Kharboutli S, et al. CD19-Targeted CAR T Cells in Refractory Systemic Lupus Erythematosus. The New England Journal of Medicine. August 2021, 385 (6): 567–569. PMID 34347960. S2CID 236927691. doi:10.1056/NEJMc2107725 .
Breslin S. Cytokine-release syndrome: overview and nursing implications. Clinical Journal of Oncology Nursing. February 2007, 11 (1 Suppl): 37–42. PMID 17471824. S2CID 35773028. doi:10.1188/07.CJON.S1.37-42.
Lee DW, Gardner R, Porter DL, Louis CU, Ahmed N, Jensen M, et al. Current concepts in the diagnosis and management of cytokine release syndrome. Blood. July 2014, 124 (2): 188–195. PMC 4093680 . PMID 24876563. doi:10.1182/blood-2014-05-552729.
Berg P, Schönefeld S, Ruppert-Seipp G, Funk MB. Regulatory Measures to Improve the Safety of CAR-T-Cell Treatment. Transfusion Medicine and Hemotherapy. 2022-11-29, 50 (3): 218–225 [2023-11-08]. ISSN 1660-3796. doi:10.1159/000526786 . （原始内容存档于2022-12-09）（英语）.
Gardner RA, Ceppi F, Rivers J, Annesley C, Summers C, Taraseviciute A, et al. Preemptive mitigation of CD19 CAR T-cell cytokine release syndrome without attenuation of antileukemic efficacy. Blood. December 2019, 134 (24): 2149–2158. PMC 6908832 . PMID 31697826. doi:10.1182/blood.2019001463.
Brudno JN, Kochenderfer JN. Toxicities of chimeric antigen receptor T cells: recognition and management. Blood. June 2016, 127 (26): 3321–3330. PMC 4929924 . PMID 27207799. doi:10.1182/blood-2016-04-703751.
Turtle CJ, Hanafi LA, Berger C, Gooley TA, Cherian S, Hudecek M, et al. CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients. The Journal of Clinical Investigation. June 2016, 126 (6): 2123–2138. PMC 4887159 . PMID 27111235. doi:10.1172/JCI85309.
Chandran SS, Klebanoff CA. T cell receptor-based cancer immunotherapy: Emerging efficacy and pathways of resistance. Immunological Reviews. July 2019, 290 (1): 127–147. PMC 7027847 . PMID 31355495. doi:10.1111/imr.12772 . Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License （页面存档备份，存于互联网档案馆）.
Dotti G, Gottschalk S, Savoldo B, Brenner MK. Design and development of therapies using chimeric antigen receptor-expressing T cells. Immunological Reviews. January 2014, 257 (1): 107–126. PMC 3874724 . PMID 24329793. doi:10.1111/imr.12131.
Zhang C, Liu J, Zhong JF, Zhang X. Engineering CAR-T cells. Biomarker Research. 2017-06-24, 5: 22. PMC 5482931 . PMID 28652918. doi:10.1186/s40364-017-0102-y .
Baldo BA. Chimeric fusion proteins used for therapy: indications, mechanisms, and safety. Drug Safety. May 2015, 38 (5): 455–479. PMID 25832756. S2CID 23852865. doi:10.1007/s40264-015-0285-9.
Li N, Fu H, Hewitt SM, Dimitrov DS, Ho M. Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America. August 2017, 114 (32): E6623–E6631. Bibcode:2017PNAS..114E6623L. PMC 5559039 . PMID 28739923. doi:10.1073/pnas.1706055114 .
Li, Nan; Quan, Alex; Li, Dan; Pan, Jiajia; Ren, Hua; Hoeltzel, Gerard; de Val, Natalia; Ashworth, Dana; Ni, Weiming; Zhou, Jing; Mackay, Sean; Hewitt, Stephen M.; Cachau, Raul; Ho, Mitchell. The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer. Nature Communications. 2023-04-08, 14 (1): 1986. Bibcode:2023NatCo..14.1986L. ISSN 2041-1723. PMC 10082787 . PMID 37031249. doi:10.1038/s41467-023-37616-4 （英语）.
Kolluri, Aarti; Li, Dan; Li, Nan; Duan, Zhijian; Roberts, Lewis R.; Ho, Mitchell. Human VH-based chimeric antigen receptor T cells targeting glypican 3 eliminate tumors in preclinical models of HCC. Hepatology Communications. 2023-02-01, 7 (2): e0022. ISSN 2471-254X. PMC 9851680 . PMID 36691969. doi:10.1097/HC9.0000000000000022.
Li, Dan; English, Hejiao; Hong, Jessica; Liang, Tianyuzhou; Merlino, Glenn; Day, Chi-Ping; Ho, Mitchell. A novel PD-L1-targeted shark VNAR single-domain-based CAR-T cell strategy for treating breast cancer and liver cancer. Molecular Therapy: Oncolytics. 2022-03-17, 24: 849–863. ISSN 2372-7705. PMC 8917269 . PMID 35317524. doi:10.1016/j.omto.2022.02.015.
Hudecek M, Sommermeyer D, Kosasih PL, Silva-Benedict A, Liu L, Rader C, et al. The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity. Cancer Immunology Research. February 2015, 3 (2): 125–135. PMC 4692801 . PMID 25212991. doi:10.1158/2326-6066.CIR-14-0127.
Qin L, Lai Y, Zhao R, Wei X, Weng J, Lai P, et al. Incorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells. Journal of Hematology & Oncology. March 2017, 10 (1): 68. PMC 5347831 . PMID 28288656. doi:10.1186/s13045-017-0437-8 .
Bridgeman JS, Hawkins RE, Bagley S, Blaylock M, Holland M, Gilham DE. The optimal antigen response of chimeric antigen receptors harboring the CD3zeta transmembrane domain is dependent upon incorporation of the receptor into the endogenous TCR/CD3 complex. Journal of Immunology. June 2010, 184 (12): 6938–6949. PMID 20483753. doi:10.4049/jimmunol.0901766 .
Sadelain M, Brentjens R, Rivière I. The basic principles of chimeric antigen receptor design. Cancer Discovery. April 2013, 3 (4): 388–398. PMC 3667586 . PMID 23550147. doi:10.1158/2159-8290.CD-12-0548.
Choe JH, Williams JZ, Lim WA. Engineering T Cells to Treat Cancer: The Convergence of Immuno-Oncology and Synthetic Biology. Annual Review of Cancer Biology. 2020, 4: 121–139. doi:10.1146/annurev-cancerbio-030419-033657 .
Cho JH, Collins JJ, Wong WW. Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses. Cell. May 2018, 173 (6): 1426–1438.e11. PMC 5984158 . PMID 29706540. doi:10.1016/j.cell.2018.03.038.
Kueberuwa G, Kalaitsidou M, Cheadle E, Hawkins RE, Gilham DE. CD19 CAR T Cells Expressing IL-12 Eradicate Lymphoma in Fully Lymphoreplete Mice through Induction of Host Immunity. Molecular Therapy: Oncolytics. March 2018, 8: 41–51. PMC 5772011 . PMID 29367945. doi:10.1016/j.omto.2017.12.003.
Chmielewski M, Abken H. TRUCKs: the fourth generation of CARs. Expert Opinion on Biological Therapy. 2015, 15 (8): 1145–1154. PMID 25985798. S2CID 42535203. doi:10.1517/14712598.2015.1046430.
Zhang E, Xu H. A new insight in chimeric antigen receptor-engineered T cells for cancer immunotherapy. Journal of Hematology & Oncology. January 2017, 10 (1): 1. PMC 5210295 . PMID 28049484. doi:10.1186/s13045-016-0379-6 .
Bonini C, Ferrari G, Verzeletti S, Servida P, Zappone E, Ruggieri L, et al. HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia. Science. June 1997, 276 (5319): 1719–1724. PMID 9180086. doi:10.1126/science.276.5319.1719.
Quintarelli C, Vera JF, Savoldo B, Giordano Attianese GM, Pule M, Foster AE, et al. Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes. Blood. October 2007, 110 (8): 2793–2802. PMC 2018664 . PMID 17638856. doi:10.1182/blood-2007-02-072843.
Riddell SR, Elliott M, Lewinsohn DA, Gilbert MJ, Wilson L, Manley SA, et al. T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients. Nature Medicine. February 1996, 2 (2): 216–223. PMID 8574968. S2CID 35503876. doi:10.1038/nm0296-216.
Maher J, Brentjens RJ, Gunset G, Rivière I, Sadelain M. Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta /CD28 receptor. Nature Biotechnology. January 2002, 20 (1): 70–75. PMID 11753365. S2CID 20302096. doi:10.1038/nbt0102-70.
Wilkie S, van Schalkwyk MC, Hobbs S, Davies DM, van der Stegen SJ, Pereira AC, et al. Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling. Journal of Clinical Immunology. October 2012, 32 (5): 1059–1070. PMID 22526592. S2CID 17660404. doi:10.1007/s10875-012-9689-9.
Wu CY, Roybal KT, Puchner EM, Onuffer J, Lim WA. Remote control of therapeutic T cells through a small molecule-gated chimeric receptor. Science. October 2015, 350 (6258): aab4077. Bibcode:2015Sci...350.4077W. PMC 4721629 . PMID 26405231. doi:10.1126/science.aab4077.
Frankel SR, Baeuerle PA. Targeting T cells to tumor cells using bispecific antibodies. Current Opinion in Chemical Biology. June 2013, 17 (3): 385–392. PMID 23623807. doi:10.1016/j.cbpa.2013.03.029.
Sun LL, Ellerman D, Mathieu M, Hristopoulos M, Chen X, Li Y, et al. Anti-CD20/CD3 T cell-dependent bispecific antibody for the treatment of B cell malignancies. Science Translational Medicine. May 2015, 7 (287): 287ra70. PMID 25972002. S2CID 24939667. doi:10.1126/scitranslmed.aaa4802.
Kim CH, Axup JY, Lawson BR, Yun H, Tardif V, Choi SH, et al. Bispecific small molecule-antibody conjugate targeting prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. October 2013, 110 (44): 17796–17801. Bibcode:2013PNAS..11017796K. PMC 3816437 . PMID 24127589. doi:10.1073/pnas.1316026110 .
Lyman GH, Nguyen A, Snyder S, Gitlin M, Chung KC. Economic Evaluation of Chimeric Antigen Receptor T-Cell Therapy by Site of Care Among Patients With Relapsed or Refractory Large B-Cell Lymphoma. JAMA Network Open. April 2020, 3 (4): e202072. PMC 7136832 . PMID 32250433. doi:10.1001/jamanetworkopen.2020.2072.
Smith, Tyrel T.; Stephan, Sirkka B.; Moffett, Howell F.; McKnight, Laura E.; Ji, Weihang; Reiman, Diana; Bonagofski, Emmy; Wohlfahrt, Martin E.; Pillai, Smitha P. S.; Stephan, Matthias T. In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers. Nature Nanotechnology. 2017-04-17, 12 (8): 813–820. ISSN 1748-3387. PMC 5646367 . PMID 28416815. doi:10.1038/nnano.2017.57.
Agarwal, Shiwani; Weidner, Tatjana; Thalheimer, Frederic B.; Buchholz, Christian J. In vivo generated human CAR T cells eradicate tumor cells. OncoImmunology. 2019-10-10, 8 (12): e1671761. ISSN 2162-402X. PMC 6844313 . PMID 31741773. doi:10.1080/2162402x.2019.1671761.
Agarwalla, Pritha; Ogunnaike, Edikan A.; Ahn, Sarah; Froehlich, Kristen A.; Jansson, Anton; Ligler, Frances S.; Dotti, Gianpietro; Brudno, Yevgeny. Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells. Nature Biotechnology. 2022-03-24, 40 (8): 1250–1258. ISSN 1087-0156. PMC 9376243 . PMID 35332339. doi:10.1038/s41587-022-01245-x.
Ghassemi, Saba; Durgin, Joseph S.; Nunez-Cruz, Selene; Patel, Jai; Leferovich, John; Pinzone, Marilia; Shen, Feng; Cummins, Katherine D.; Plesa, Gabriela; Cantu, Vito Adrian; Reddy, Shantan; Bushman, Frederic D.; Gill, Saar I.; O'Doherty, Una; O'Connor, Roddy S. Rapid manufacturing of non-activated potent CAR T cells. Nature Biomedical Engineering. February 2022, 6 (2): 118–128. ISSN 2157-846X. PMC 8860360 . PMID 35190680. doi:10.1038/s41551-021-00842-6 （英语）.
Ledford, Heidi. Cancer-fighting CAR-T cells could be made inside body with viral injection. Nature. 2023-12-20 [2023-12-29]. doi:10.1038/d41586-023-03969-5. （原始内容存档于2023-12-28）（英语）.
Fiorenza S, Ritchie DS, Ramsey SD, Turtle CJ, Roth JA. Value and affordability of CAR T-cell therapy in the United States. Bone Marrow Transplantation. September 2020, 55 (9): 1706–1715. PMID 32474570. S2CID 218987876. doi:10.1038/s41409-020-0956-8.

dx.doi.org

Smith, Tyrel T.; Stephan, Sirkka B.; Moffett, Howell F.; McKnight, Laura E.; Ji, Weihang; Reiman, Diana; Bonagofski, Emmy; Wohlfahrt, Martin E.; Pillai, Smitha P. S.; Stephan, Matthias T. In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers. Nature Nanotechnology. 2017-04-17, 12 (8): 813–820. ISSN 1748-3387. PMC 5646367 . PMID 28416815. doi:10.1038/nnano.2017.57.
Agarwal, Shiwani; Weidner, Tatjana; Thalheimer, Frederic B.; Buchholz, Christian J. In vivo generated human CAR T cells eradicate tumor cells. OncoImmunology. 2019-10-10, 8 (12): e1671761. ISSN 2162-402X. PMC 6844313 . PMID 31741773. doi:10.1080/2162402x.2019.1671761.
Agarwalla, Pritha; Ogunnaike, Edikan A.; Ahn, Sarah; Froehlich, Kristen A.; Jansson, Anton; Ligler, Frances S.; Dotti, Gianpietro; Brudno, Yevgeny. Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells. Nature Biotechnology. 2022-03-24, 40 (8): 1250–1258. ISSN 1087-0156. PMC 9376243 . PMID 35332339. doi:10.1038/s41587-022-01245-x.

endocyte.com

SMDC technology. 互联网档案馆的存檔，存档日期2016-03-27. ENDOCYTE

investor.endocyte.com

Endocyte announces promising preclinical data for application of SMDC technology in CAR T cell therapy in late-breaking abstract at American Association for Cancer Research (AACR) annual meeting 2016 (新闻稿). Endocyte. April 19, 2016 [December 20, 2017]. （原始内容存档于July 30, 2017）.

fda.gov

Center for Biologics Evaluation and Research. Approved Cellular and Gene Therapy Products. FDA. 2022-03-01 [2023-10-07]. （原始内容存档于2023-12-20）（英语）.

gov.br

Anvisa aprova produto de terapia avançada para tratamento de câncer. Agência Nacional de Vigilância Sanitária - Anvisa. 2022-02-23 [2022-06-07]. （原始内容存档于2023-12-15）（巴西葡萄牙语）.

harvard.edu

ui.adsabs.harvard.edu

Gross G, Waks T, Eshhar Z. Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity. Proceedings of the National Academy of Sciences of the United States of America. December 1989, 86 (24): 10024–10028. Bibcode:1989PNAS...8610024G. JSTOR 34790. PMC 298636 . PMID 2513569. doi:10.1073/pnas.86.24.10024 .
Li, Nan; Fu, Haiying; Hewitt, Stephen M.; Dimitrov, Dimiter S.; Ho, Mitchell. Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America. 2017-08-08, 114 (32): E6623–E6631. Bibcode:2017PNAS..114E6623L. ISSN 1091-6490. PMC 5559039 . PMID 28739923. doi:10.1073/pnas.1706055114 .
Li N, Fu H, Hewitt SM, Dimitrov DS, Ho M. Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America. August 2017, 114 (32): E6623–E6631. Bibcode:2017PNAS..114E6623L. PMC 5559039 . PMID 28739923. doi:10.1073/pnas.1706055114 .
Li, Nan; Quan, Alex; Li, Dan; Pan, Jiajia; Ren, Hua; Hoeltzel, Gerard; de Val, Natalia; Ashworth, Dana; Ni, Weiming; Zhou, Jing; Mackay, Sean; Hewitt, Stephen M.; Cachau, Raul; Ho, Mitchell. The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer. Nature Communications. 2023-04-08, 14 (1): 1986. Bibcode:2023NatCo..14.1986L. ISSN 2041-1723. PMC 10082787 . PMID 37031249. doi:10.1038/s41467-023-37616-4 （英语）.
Wu CY, Roybal KT, Puchner EM, Onuffer J, Lim WA. Remote control of therapeutic T cells through a small molecule-gated chimeric receptor. Science. October 2015, 350 (6258): aab4077. Bibcode:2015Sci...350.4077W. PMC 4721629 . PMID 26405231. doi:10.1126/science.aab4077.
Kim CH, Axup JY, Lawson BR, Yun H, Tardif V, Choi SH, et al. Bispecific small molecule-antibody conjugate targeting prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. October 2013, 110 (44): 17796–17801. Bibcode:2013PNAS..11017796K. PMC 3816437 . PMID 24127589. doi:10.1073/pnas.1316026110 .

hematology.org

CAR T-cell Therapy: An Update on Coverage and Reimbursement - Hematology.org. www.hematology.org. [2021-03-22]. （原始内容存档于2022-01-24）（英语）.

jstor.org

Gross G, Waks T, Eshhar Z. Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity. Proceedings of the National Academy of Sciences of the United States of America. December 1989, 86 (24): 10024–10028. Bibcode:1989PNAS...8610024G. JSTOR 34790. PMC 298636 . PMID 2513569. doi:10.1073/pnas.86.24.10024 .

karger.com

Berg P, Schönefeld S, Ruppert-Seipp G, Funk MB. Regulatory Measures to Improve the Safety of CAR-T-Cell Treatment. Transfusion Medicine and Hemotherapy. 2022-11-29, 50 (3): 218–225 [2023-11-08]. ISSN 1660-3796. doi:10.1159/000526786 . （原始内容存档于2022-12-09）（英语）.

labiotech.eu

A Cure for Cancer? How CAR-T Therapy is Revolutionizing Oncology. (新闻稿). labiotech. March 8, 2018 [April 19, 2018]. （原始内容存档于2018-07-26）.

nature.com

Ledford, Heidi. Cancer-fighting CAR-T cells could be made inside body with viral injection. Nature. 2023-12-20 [2023-12-29]. doi:10.1038/d41586-023-03969-5. （原始内容存档于2023-12-28）（英语）.

nbcnews.com

Fox, Maggie. New Gene Therapy for Cancer Offers Hope to Those With No Options Left. NBC News. July 12, 2017 [2019-05-03]. （原始内容存档于2019-05-23）.

nih.gov

ncbi.nlm.nih.gov

Srivastava S, Riddell SR. Engineering CAR-T cells: Design concepts. Trends in Immunology. August 2015, 36 (8): 494–502. PMC 4746114 . PMID 26169254. doi:10.1016/j.it.2015.06.004.
Hartmann J, Schüßler-Lenz M, Bondanza A, Buchholz CJ. Clinical development of CAR T cells-challenges and opportunities in translating innovative treatment concepts. EMBO Molecular Medicine. September 2017, 9 (9): 1183–1197. PMC 5582407 . PMID 28765140. doi:10.15252/emmm.201607485.
Tang XJ, Sun XY, Huang KM, Zhang L, Yang ZS, Zou DD, et al. Therapeutic potential of CAR-T cell-derived exosomes: a cell-free modality for targeted cancer therapy. Oncotarget. December 2015, 6 (42): 44179–44190. PMC 4792550 . PMID 26496034. doi:10.18632/oncotarget.6175.
Zhang H, Zhao P, Huang H. Engineering better chimeric antigen receptor T cells. Experimental Hematology & Oncology. December 2020, 9 (1): 34. PMC 7709221 . PMID 33292660. doi:10.1186/s40164-020-00190-2.
Bupha-Intr O, Haeusler G, Chee L, Thursky K, Slavin M, Teh B. CAR-T cell therapy and infection: a review. Expert Review of Anti-Infective Therapy. June 2021, 19 (6): 749–758. PMID 33249873. S2CID 227235627. doi:10.1080/14787210.2021.1855143.
Bonifant CL, Jackson HJ, Brentjens RJ, Curran KJ. Toxicity and management in CAR T-cell therapy. Molecular Therapy: Oncolytics. 2016, 3: 16011. PMC 5008265 . PMID 27626062. doi:10.1038/mto.2016.11.
Kuwana Y, Asakura Y, Utsunomiya N, Nakanishi M, Arata Y, Itoh S, et al. Expression of chimeric receptor composed of immunoglobulin-derived V regions and T-cell receptor-derived C regions. Biochemical and Biophysical Research Communications. December 1987, 149 (3): 960–968. PMID 3122749. doi:10.1016/0006-291x(87)90502-x.
Gross G, Gorochov G, Waks T, Eshhar Z. Generation of effector T cells expressing chimeric T cell receptor with antibody type-specificity. Transplantation Proceedings. February 1989, 21 (1 Pt 1): 127–130. PMID 2784887.
Rosenbaum L. Tragedy, Perseverance, and Chance - The Story of CAR-T Therapy. The New England Journal of Medicine. October 2017, 377 (14): 1313–1315. PMID 28902570. doi:10.1056/NEJMp1711886.
Gross G, Waks T, Eshhar Z. Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity. Proceedings of the National Academy of Sciences of the United States of America. December 1989, 86 (24): 10024–10028. Bibcode:1989PNAS...8610024G. JSTOR 34790. PMC 298636 . PMID 2513569. doi:10.1073/pnas.86.24.10024 .
Eshhar Z, Bach N, Fitzer-Attas CJ, Gross G, Lustgarten J, Waks T, Schindler DG. The T-body approach: potential for cancer immunotherapy. Springer Seminars in Immunopathology. 1996, 18 (2): 199–209. PMID 8908700. S2CID 19872173. doi:10.1007/BF00820666.
Irving BA, Weiss A. The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways. Cell. March 1991, 64 (5): 891–901. PMID 1705867. S2CID 23466990. doi:10.1016/0092-8674(91)90314-o.
Hege KM, Roberts MR. T-cell gene therapy. Current Opinion in Biotechnology. December 1996, 7 (6): 629–634. PMID 8939644. doi:10.1016/s0958-1669(96)80074-7.
June CH, Sadelain M. Chimeric Antigen Receptor Therapy. The New England Journal of Medicine. July 2018, 379 (1): 64–73. PMC 7433347 . PMID 29972754. doi:10.1056/NEJMra1706169.
Braendstrup P, Levine BL, Ruella M. The long road to the first FDA-approved gene therapy: chimeric antigen receptor T cells targeting CD19. Cytotherapy. February 2020, 22 (2): 57–69. PMC 7036015 . PMID 32014447. doi:10.1016/j.jcyt.2019.12.004.
Sadelain M, Rivière I, Brentjens R. Targeting tumours with genetically enhanced T lymphocytes. Nature Reviews. Cancer. January 2003, 3 (1): 35–45. PMID 12509765. S2CID 33707802. doi:10.1038/nrc971.
Jin C, Yu D, Hillerdal V, Wallgren A, Karlsson-Parra A, Essand M. Allogeneic lymphocyte-licensed DCs expand T cells with improved antitumor activity and resistance to oxidative stress and immunosuppressive factors. Molecular Therapy: Methods & Clinical Development. 2014-03-05, 1: 14001. PMC 4362340 . PMID 26015949. doi:10.1038/mtm.2014.1.
Li, Nan; Ho, Mitchell. Development of Glypican-2 Targeting Single-Domain Antibody CAR T Cells for Neuroblastoma. Single-Domain Antibodies. Methods in Molecular Biology 2446. 2022: 451–468 [2023-10-11]. ISBN 978-1-0716-2074-8. ISSN 1940-6029. PMID 35157288. S2CID 246813053. doi:10.1007/978-1-0716-2075-5_23. （原始内容存档于2023-12-16）.
Makita S, Yoshimura K, Tobinai K. Clinical development of anti-CD19 chimeric antigen receptor T-cell therapy for B-cell non-Hodgkin lymphoma. Cancer Science. June 2017, 108 (6): 1109–1118. PMC 5480083 . PMID 28301076. doi:10.1111/cas.13239.
Jin C, Fotaki G, Ramachandran M, Nilsson B, Essand M, Yu D. Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer. EMBO Molecular Medicine. July 2016, 8 (7): 702–711. PMC 4931286 . PMID 27189167. doi:10.15252/emmm.201505869.
Jensen TI, Axelgaard E, Bak RO. Therapeutic gene editing in haematological disorders with CRISPR/Cas9. British Journal of Haematology. June 2019, 185 (5): 821–835. PMID 30864164. doi:10.1111/bjh.15851 .
Muranski P, Boni A, Wrzesinski C, Citrin DE, Rosenberg SA, Childs R, Restifo NP. Increased intensity lymphodepletion and adoptive immunotherapy--how far can we go?. Nature Clinical Practice. Oncology. December 2006, 3 (12): 668–681. PMC 1773008 . PMID 17139318. doi:10.1038/ncponc0666.
Xin Yu J, Hubbard-Lucey VM, Tang J. The global pipeline of cell therapies for cancer. Nature Reviews. Drug Discovery. October 2019, 18 (11): 821–822. PMID 31673124. S2CID 190862546. doi:10.1038/d41573-019-00090-z.
Almåsbak H, Aarvak T, Vemuri MC. CAR T Cell Therapy: A Game Changer in Cancer Treatment. Journal of Immunology Research. 2016, 2016: 5474602. PMC 4889848 . PMID 27298832. doi:10.1155/2016/5474602 .
Jacobson CA, Ritz J. Time to put the CAR-T before the horse. Blood. November 2011, 118 (18): 4761–4762. PMID 22053170. doi:10.1182/blood-2011-09-376137 .
Li, Nan; Spetz, Madeline R.; Li, Dan; Ho, Mitchell. Advances in immunotherapeutic targets for childhood cancers: A focus on glypican-2 and B7-H3. Pharmacology & Therapeutics. July 2021, 223: 107892. ISSN 1879-016X. PMC 8202769 . PMID 33992682. doi:10.1016/j.pharmthera.2021.107892.
Li, Dan; Lin, Shaoli; Hong, Jessica; Ho, Mitchell. Immunotherapy for hepatobiliary cancers: Emerging targets and translational advances. Advances in Cancer Research. 2022, 156: 415–449 [2023-10-19]. ISBN 9780323983921. ISSN 2162-5557. PMID 35961708. S2CID 246978004. doi:10.1016/bs.acr.2022.01.013. （原始内容存档于2023-12-16）.
Kochenderfer JN, Wilson WH, Janik JE, Dudley ME, Stetler-Stevenson M, Feldman SA, et al. Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19. Blood. November 2010, 116 (20): 4099–4102. PMC 2993617 . PMID 20668228. doi:10.1182/blood-2010-04-281931 .
Kochenderfer JN, Dudley ME, Kassim SH, Somerville RP, Carpenter RO, Stetler-Stevenson M, et al. Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor. Journal of Clinical Oncology. February 2015, 33 (6): 540–549. PMC 4322257 . PMID 25154820. doi:10.1200/JCO.2014.56.2025.
Schultz L, Mackall C. Driving CAR T cell translation forward. Science Translational Medicine. February 2019, 11 (481): eaaw2127. PMID 30814337. doi:10.1126/scitranslmed.aaw2127 .
Lim WA, June CH. The Principles of Engineering Immune Cells to Treat Cancer. Cell. February 2017, 168 (4): 724–740. PMC 5553442 . PMID 28187291. doi:10.1016/j.cell.2017.01.016.
Li D, Li N, Zhang YF, Fu H, Feng M, Schneider D, et al. Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice. Gastroenterology. June 2020, 158 (8): 2250–2265.e20. PMC 7282931 . PMID 32060001. doi:10.1053/j.gastro.2020.02.011.
Li, Nan; Fu, Haiying; Hewitt, Stephen M.; Dimitrov, Dimiter S.; Ho, Mitchell. Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America. 2017-08-08, 114 (32): E6623–E6631. Bibcode:2017PNAS..114E6623L. ISSN 1091-6490. PMC 5559039 . PMID 28739923. doi:10.1073/pnas.1706055114 .
Li, Nan; Torres, Madeline B.; Spetz, Madeline R.; Wang, Ruixue; Peng, Luyi; Tian, Meijie; Dower, Christopher M.; Nguyen, Rosa; Sun, Ming; Tai, Chin-Hsien; de Val, Natalia; Cachau, Raul; Wu, Xiaolin; Hewitt, Stephen M.; Kaplan, Rosandra N. CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice. Cell Reports. Medicine. 2021-06-15, 2 (6): 100297. ISSN 2666-3791. PMC 8233664 . PMID 34195677. doi:10.1016/j.xcrm.2021.100297.
Zhang Q, Lu W, Liang CL, Chen Y, Liu H, Qiu F, Dai Z. Chimeric Antigen Receptor (CAR) Treg: A Promising Approach to Inducing Immunological Tolerance. Frontiers in Immunology. 2018, 9: 2359. PMC 6194362 . PMID 30369931. doi:10.3389/fimmu.2018.02359 .
Mougiakakos D, Krönke G, Völkl S, Kretschmann S, Aigner M, Kharboutli S, et al. CD19-Targeted CAR T Cells in Refractory Systemic Lupus Erythematosus. The New England Journal of Medicine. August 2021, 385 (6): 567–569. PMID 34347960. S2CID 236927691. doi:10.1056/NEJMc2107725 .
Breslin S. Cytokine-release syndrome: overview and nursing implications. Clinical Journal of Oncology Nursing. February 2007, 11 (1 Suppl): 37–42. PMID 17471824. S2CID 35773028. doi:10.1188/07.CJON.S1.37-42.
Lee DW, Gardner R, Porter DL, Louis CU, Ahmed N, Jensen M, et al. Current concepts in the diagnosis and management of cytokine release syndrome. Blood. July 2014, 124 (2): 188–195. PMC 4093680 . PMID 24876563. doi:10.1182/blood-2014-05-552729.
Gardner RA, Ceppi F, Rivers J, Annesley C, Summers C, Taraseviciute A, et al. Preemptive mitigation of CD19 CAR T-cell cytokine release syndrome without attenuation of antileukemic efficacy. Blood. December 2019, 134 (24): 2149–2158. PMC 6908832 . PMID 31697826. doi:10.1182/blood.2019001463.
Brudno JN, Kochenderfer JN. Toxicities of chimeric antigen receptor T cells: recognition and management. Blood. June 2016, 127 (26): 3321–3330. PMC 4929924 . PMID 27207799. doi:10.1182/blood-2016-04-703751.
Turtle CJ, Hanafi LA, Berger C, Gooley TA, Cherian S, Hudecek M, et al. CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients. The Journal of Clinical Investigation. June 2016, 126 (6): 2123–2138. PMC 4887159 . PMID 27111235. doi:10.1172/JCI85309.
Chandran SS, Klebanoff CA. T cell receptor-based cancer immunotherapy: Emerging efficacy and pathways of resistance. Immunological Reviews. July 2019, 290 (1): 127–147. PMC 7027847 . PMID 31355495. doi:10.1111/imr.12772 . Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License （页面存档备份，存于互联网档案馆）.
Dotti G, Gottschalk S, Savoldo B, Brenner MK. Design and development of therapies using chimeric antigen receptor-expressing T cells. Immunological Reviews. January 2014, 257 (1): 107–126. PMC 3874724 . PMID 24329793. doi:10.1111/imr.12131.
Zhang C, Liu J, Zhong JF, Zhang X. Engineering CAR-T cells. Biomarker Research. 2017-06-24, 5: 22. PMC 5482931 . PMID 28652918. doi:10.1186/s40364-017-0102-y .
Baldo BA. Chimeric fusion proteins used for therapy: indications, mechanisms, and safety. Drug Safety. May 2015, 38 (5): 455–479. PMID 25832756. S2CID 23852865. doi:10.1007/s40264-015-0285-9.
Li N, Fu H, Hewitt SM, Dimitrov DS, Ho M. Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America. August 2017, 114 (32): E6623–E6631. Bibcode:2017PNAS..114E6623L. PMC 5559039 . PMID 28739923. doi:10.1073/pnas.1706055114 .
Li, Nan; Quan, Alex; Li, Dan; Pan, Jiajia; Ren, Hua; Hoeltzel, Gerard; de Val, Natalia; Ashworth, Dana; Ni, Weiming; Zhou, Jing; Mackay, Sean; Hewitt, Stephen M.; Cachau, Raul; Ho, Mitchell. The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer. Nature Communications. 2023-04-08, 14 (1): 1986. Bibcode:2023NatCo..14.1986L. ISSN 2041-1723. PMC 10082787 . PMID 37031249. doi:10.1038/s41467-023-37616-4 （英语）.
Kolluri, Aarti; Li, Dan; Li, Nan; Duan, Zhijian; Roberts, Lewis R.; Ho, Mitchell. Human VH-based chimeric antigen receptor T cells targeting glypican 3 eliminate tumors in preclinical models of HCC. Hepatology Communications. 2023-02-01, 7 (2): e0022. ISSN 2471-254X. PMC 9851680 . PMID 36691969. doi:10.1097/HC9.0000000000000022.
Li, Dan; English, Hejiao; Hong, Jessica; Liang, Tianyuzhou; Merlino, Glenn; Day, Chi-Ping; Ho, Mitchell. A novel PD-L1-targeted shark VNAR single-domain-based CAR-T cell strategy for treating breast cancer and liver cancer. Molecular Therapy: Oncolytics. 2022-03-17, 24: 849–863. ISSN 2372-7705. PMC 8917269 . PMID 35317524. doi:10.1016/j.omto.2022.02.015.
Hudecek M, Sommermeyer D, Kosasih PL, Silva-Benedict A, Liu L, Rader C, et al. The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity. Cancer Immunology Research. February 2015, 3 (2): 125–135. PMC 4692801 . PMID 25212991. doi:10.1158/2326-6066.CIR-14-0127.
Qin L, Lai Y, Zhao R, Wei X, Weng J, Lai P, et al. Incorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells. Journal of Hematology & Oncology. March 2017, 10 (1): 68. PMC 5347831 . PMID 28288656. doi:10.1186/s13045-017-0437-8 .
Bridgeman JS, Hawkins RE, Bagley S, Blaylock M, Holland M, Gilham DE. The optimal antigen response of chimeric antigen receptors harboring the CD3zeta transmembrane domain is dependent upon incorporation of the receptor into the endogenous TCR/CD3 complex. Journal of Immunology. June 2010, 184 (12): 6938–6949. PMID 20483753. doi:10.4049/jimmunol.0901766 .
Sadelain M, Brentjens R, Rivière I. The basic principles of chimeric antigen receptor design. Cancer Discovery. April 2013, 3 (4): 388–398. PMC 3667586 . PMID 23550147. doi:10.1158/2159-8290.CD-12-0548.
Cho JH, Collins JJ, Wong WW. Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses. Cell. May 2018, 173 (6): 1426–1438.e11. PMC 5984158 . PMID 29706540. doi:10.1016/j.cell.2018.03.038.
Kueberuwa G, Kalaitsidou M, Cheadle E, Hawkins RE, Gilham DE. CD19 CAR T Cells Expressing IL-12 Eradicate Lymphoma in Fully Lymphoreplete Mice through Induction of Host Immunity. Molecular Therapy: Oncolytics. March 2018, 8: 41–51. PMC 5772011 . PMID 29367945. doi:10.1016/j.omto.2017.12.003.
Chmielewski M, Abken H. TRUCKs: the fourth generation of CARs. Expert Opinion on Biological Therapy. 2015, 15 (8): 1145–1154. PMID 25985798. S2CID 42535203. doi:10.1517/14712598.2015.1046430.
Zhang E, Xu H. A new insight in chimeric antigen receptor-engineered T cells for cancer immunotherapy. Journal of Hematology & Oncology. January 2017, 10 (1): 1. PMC 5210295 . PMID 28049484. doi:10.1186/s13045-016-0379-6 .
Bonini C, Ferrari G, Verzeletti S, Servida P, Zappone E, Ruggieri L, et al. HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia. Science. June 1997, 276 (5319): 1719–1724. PMID 9180086. doi:10.1126/science.276.5319.1719.
Quintarelli C, Vera JF, Savoldo B, Giordano Attianese GM, Pule M, Foster AE, et al. Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes. Blood. October 2007, 110 (8): 2793–2802. PMC 2018664 . PMID 17638856. doi:10.1182/blood-2007-02-072843.
Riddell SR, Elliott M, Lewinsohn DA, Gilbert MJ, Wilson L, Manley SA, et al. T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients. Nature Medicine. February 1996, 2 (2): 216–223. PMID 8574968. S2CID 35503876. doi:10.1038/nm0296-216.
Maher J, Brentjens RJ, Gunset G, Rivière I, Sadelain M. Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta /CD28 receptor. Nature Biotechnology. January 2002, 20 (1): 70–75. PMID 11753365. S2CID 20302096. doi:10.1038/nbt0102-70.
Wilkie S, van Schalkwyk MC, Hobbs S, Davies DM, van der Stegen SJ, Pereira AC, et al. Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling. Journal of Clinical Immunology. October 2012, 32 (5): 1059–1070. PMID 22526592. S2CID 17660404. doi:10.1007/s10875-012-9689-9.
Wu CY, Roybal KT, Puchner EM, Onuffer J, Lim WA. Remote control of therapeutic T cells through a small molecule-gated chimeric receptor. Science. October 2015, 350 (6258): aab4077. Bibcode:2015Sci...350.4077W. PMC 4721629 . PMID 26405231. doi:10.1126/science.aab4077.
Frankel SR, Baeuerle PA. Targeting T cells to tumor cells using bispecific antibodies. Current Opinion in Chemical Biology. June 2013, 17 (3): 385–392. PMID 23623807. doi:10.1016/j.cbpa.2013.03.029.
Sun LL, Ellerman D, Mathieu M, Hristopoulos M, Chen X, Li Y, et al. Anti-CD20/CD3 T cell-dependent bispecific antibody for the treatment of B cell malignancies. Science Translational Medicine. May 2015, 7 (287): 287ra70. PMID 25972002. S2CID 24939667. doi:10.1126/scitranslmed.aaa4802.
Kim CH, Axup JY, Lawson BR, Yun H, Tardif V, Choi SH, et al. Bispecific small molecule-antibody conjugate targeting prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. October 2013, 110 (44): 17796–17801. Bibcode:2013PNAS..11017796K. PMC 3816437 . PMID 24127589. doi:10.1073/pnas.1316026110 .
Lyman GH, Nguyen A, Snyder S, Gitlin M, Chung KC. Economic Evaluation of Chimeric Antigen Receptor T-Cell Therapy by Site of Care Among Patients With Relapsed or Refractory Large B-Cell Lymphoma. JAMA Network Open. April 2020, 3 (4): e202072. PMC 7136832 . PMID 32250433. doi:10.1001/jamanetworkopen.2020.2072.
Smith, Tyrel T.; Stephan, Sirkka B.; Moffett, Howell F.; McKnight, Laura E.; Ji, Weihang; Reiman, Diana; Bonagofski, Emmy; Wohlfahrt, Martin E.; Pillai, Smitha P. S.; Stephan, Matthias T. In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers. Nature Nanotechnology. 2017-04-17, 12 (8): 813–820. ISSN 1748-3387. PMC 5646367 . PMID 28416815. doi:10.1038/nnano.2017.57.
Agarwal, Shiwani; Weidner, Tatjana; Thalheimer, Frederic B.; Buchholz, Christian J. In vivo generated human CAR T cells eradicate tumor cells. OncoImmunology. 2019-10-10, 8 (12): e1671761. ISSN 2162-402X. PMC 6844313 . PMID 31741773. doi:10.1080/2162402x.2019.1671761.
Agarwalla, Pritha; Ogunnaike, Edikan A.; Ahn, Sarah; Froehlich, Kristen A.; Jansson, Anton; Ligler, Frances S.; Dotti, Gianpietro; Brudno, Yevgeny. Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells. Nature Biotechnology. 2022-03-24, 40 (8): 1250–1258. ISSN 1087-0156. PMC 9376243 . PMID 35332339. doi:10.1038/s41587-022-01245-x.
Ghassemi, Saba; Durgin, Joseph S.; Nunez-Cruz, Selene; Patel, Jai; Leferovich, John; Pinzone, Marilia; Shen, Feng; Cummins, Katherine D.; Plesa, Gabriela; Cantu, Vito Adrian; Reddy, Shantan; Bushman, Frederic D.; Gill, Saar I.; O'Doherty, Una; O'Connor, Roddy S. Rapid manufacturing of non-activated potent CAR T cells. Nature Biomedical Engineering. February 2022, 6 (2): 118–128. ISSN 2157-846X. PMC 8860360 . PMID 35190680. doi:10.1038/s41551-021-00842-6 （英语）.
Fiorenza S, Ritchie DS, Ramsey SD, Turtle CJ, Roth JA. Value and affordability of CAR T-cell therapy in the United States. Bone Marrow Transplantation. September 2020, 55 (9): 1706–1715. PMID 32474570. S2CID 218987876. doi:10.1038/s41409-020-0956-8.

pubmed.ncbi.nlm.nih.gov

Li, Nan; Ho, Mitchell. Development of Glypican-2 Targeting Single-Domain Antibody CAR T Cells for Neuroblastoma. Single-Domain Antibodies. Methods in Molecular Biology 2446. 2022: 451–468 [2023-10-11]. ISBN 978-1-0716-2074-8. ISSN 1940-6029. PMID 35157288. S2CID 246813053. doi:10.1007/978-1-0716-2075-5_23. （原始内容存档于2023-12-16）.
Li, Dan; Lin, Shaoli; Hong, Jessica; Ho, Mitchell. Immunotherapy for hepatobiliary cancers: Emerging targets and translational advances. Advances in Cancer Research. 2022, 156: 415–449 [2023-10-19]. ISBN 9780323983921. ISSN 2162-5557. PMID 35961708. S2CID 246978004. doi:10.1016/bs.acr.2022.01.013. （原始内容存档于2023-12-16）.

semanticscholar.org

api.semanticscholar.org

Bupha-Intr O, Haeusler G, Chee L, Thursky K, Slavin M, Teh B. CAR-T cell therapy and infection: a review. Expert Review of Anti-Infective Therapy. June 2021, 19 (6): 749–758. PMID 33249873. S2CID 227235627. doi:10.1080/14787210.2021.1855143.
Eshhar Z, Bach N, Fitzer-Attas CJ, Gross G, Lustgarten J, Waks T, Schindler DG. The T-body approach: potential for cancer immunotherapy. Springer Seminars in Immunopathology. 1996, 18 (2): 199–209. PMID 8908700. S2CID 19872173. doi:10.1007/BF00820666.
Irving BA, Weiss A. The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways. Cell. March 1991, 64 (5): 891–901. PMID 1705867. S2CID 23466990. doi:10.1016/0092-8674(91)90314-o.
Sadelain M, Rivière I, Brentjens R. Targeting tumours with genetically enhanced T lymphocytes. Nature Reviews. Cancer. January 2003, 3 (1): 35–45. PMID 12509765. S2CID 33707802. doi:10.1038/nrc971.
Li, Nan; Ho, Mitchell. Development of Glypican-2 Targeting Single-Domain Antibody CAR T Cells for Neuroblastoma. Single-Domain Antibodies. Methods in Molecular Biology 2446. 2022: 451–468 [2023-10-11]. ISBN 978-1-0716-2074-8. ISSN 1940-6029. PMID 35157288. S2CID 246813053. doi:10.1007/978-1-0716-2075-5_23. （原始内容存档于2023-12-16）.
Xin Yu J, Hubbard-Lucey VM, Tang J. The global pipeline of cell therapies for cancer. Nature Reviews. Drug Discovery. October 2019, 18 (11): 821–822. PMID 31673124. S2CID 190862546. doi:10.1038/d41573-019-00090-z.
Li, Dan; Lin, Shaoli; Hong, Jessica; Ho, Mitchell. Immunotherapy for hepatobiliary cancers: Emerging targets and translational advances. Advances in Cancer Research. 2022, 156: 415–449 [2023-10-19]. ISBN 9780323983921. ISSN 2162-5557. PMID 35961708. S2CID 246978004. doi:10.1016/bs.acr.2022.01.013. （原始内容存档于2023-12-16）.
Mougiakakos D, Krönke G, Völkl S, Kretschmann S, Aigner M, Kharboutli S, et al. CD19-Targeted CAR T Cells in Refractory Systemic Lupus Erythematosus. The New England Journal of Medicine. August 2021, 385 (6): 567–569. PMID 34347960. S2CID 236927691. doi:10.1056/NEJMc2107725 .
Breslin S. Cytokine-release syndrome: overview and nursing implications. Clinical Journal of Oncology Nursing. February 2007, 11 (1 Suppl): 37–42. PMID 17471824. S2CID 35773028. doi:10.1188/07.CJON.S1.37-42.
Baldo BA. Chimeric fusion proteins used for therapy: indications, mechanisms, and safety. Drug Safety. May 2015, 38 (5): 455–479. PMID 25832756. S2CID 23852865. doi:10.1007/s40264-015-0285-9.
Chmielewski M, Abken H. TRUCKs: the fourth generation of CARs. Expert Opinion on Biological Therapy. 2015, 15 (8): 1145–1154. PMID 25985798. S2CID 42535203. doi:10.1517/14712598.2015.1046430.
Riddell SR, Elliott M, Lewinsohn DA, Gilbert MJ, Wilson L, Manley SA, et al. T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients. Nature Medicine. February 1996, 2 (2): 216–223. PMID 8574968. S2CID 35503876. doi:10.1038/nm0296-216.
Maher J, Brentjens RJ, Gunset G, Rivière I, Sadelain M. Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta /CD28 receptor. Nature Biotechnology. January 2002, 20 (1): 70–75. PMID 11753365. S2CID 20302096. doi:10.1038/nbt0102-70.
Wilkie S, van Schalkwyk MC, Hobbs S, Davies DM, van der Stegen SJ, Pereira AC, et al. Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling. Journal of Clinical Immunology. October 2012, 32 (5): 1059–1070. PMID 22526592. S2CID 17660404. doi:10.1007/s10875-012-9689-9.
Sun LL, Ellerman D, Mathieu M, Hristopoulos M, Chen X, Li Y, et al. Anti-CD20/CD3 T cell-dependent bispecific antibody for the treatment of B cell malignancies. Science Translational Medicine. May 2015, 7 (287): 287ra70. PMID 25972002. S2CID 24939667. doi:10.1126/scitranslmed.aaa4802.
Fiorenza S, Ritchie DS, Ramsey SD, Turtle CJ, Roth JA. Value and affordability of CAR T-cell therapy in the United States. Bone Marrow Transplantation. September 2020, 55 (9): 1706–1715. PMID 32474570. S2CID 218987876. doi:10.1038/s41409-020-0956-8.

susupport.com

Eder M. Which countries is CAR T-cell therapy available in? | SingleUseSupport. 25 November 2021 [13 May 2022]. （原始内容存档于2021-12-06）.

web.archive.org

Fox, Maggie. New Gene Therapy for Cancer Offers Hope to Those With No Options Left. NBC News. July 12, 2017 [2019-05-03]. （原始内容存档于2019-05-23）.
Center for Biologics Evaluation and Research. Approved Cellular and Gene Therapy Products. FDA. 2022-03-01 [2023-10-07]. （原始内容存档于2023-12-20）（英语）.
Li, Nan; Ho, Mitchell. Development of Glypican-2 Targeting Single-Domain Antibody CAR T Cells for Neuroblastoma. Single-Domain Antibodies. Methods in Molecular Biology 2446. 2022: 451–468 [2023-10-11]. ISBN 978-1-0716-2074-8. ISSN 1940-6029. PMID 35157288. S2CID 246813053. doi:10.1007/978-1-0716-2075-5_23. （原始内容存档于2023-12-16）.
Li, Dan; Lin, Shaoli; Hong, Jessica; Ho, Mitchell. Immunotherapy for hepatobiliary cancers: Emerging targets and translational advances. Advances in Cancer Research. 2022, 156: 415–449 [2023-10-19]. ISBN 9780323983921. ISSN 2162-5557. PMID 35961708. S2CID 246978004. doi:10.1016/bs.acr.2022.01.013. （原始内容存档于2023-12-16）.
Berg P, Schönefeld S, Ruppert-Seipp G, Funk MB. Regulatory Measures to Improve the Safety of CAR-T-Cell Treatment. Transfusion Medicine and Hemotherapy. 2022-11-29, 50 (3): 218–225 [2023-11-08]. ISSN 1660-3796. doi:10.1159/000526786 . （原始内容存档于2022-12-09）（英语）.
Study Evaluating the Efficacy and Safety of JCAR015 in Adult B-cell Acute Lymphoblastic Leukemia (B-ALL). ClinicalTrials.gov. [2018-02-21]. （原始内容存档于2023-04-05）.
Chandran SS, Klebanoff CA. T cell receptor-based cancer immunotherapy: Emerging efficacy and pathways of resistance. Immunological Reviews. July 2019, 290 (1): 127–147. PMC 7027847 . PMID 31355495. doi:10.1111/imr.12772 . Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License （页面存档备份，存于互联网档案馆）.
A Cure for Cancer? How CAR-T Therapy is Revolutionizing Oncology. (新闻稿). labiotech. March 8, 2018 [April 19, 2018]. （原始内容存档于2018-07-26）.
SMDC technology. 互联网档案馆的存檔，存档日期2016-03-27. ENDOCYTE
Endocyte announces promising preclinical data for application of SMDC technology in CAR T cell therapy in late-breaking abstract at American Association for Cancer Research (AACR) annual meeting 2016 (新闻稿). Endocyte. April 19, 2016 [December 20, 2017]. （原始内容存档于July 30, 2017）.
Ledford, Heidi. Cancer-fighting CAR-T cells could be made inside body with viral injection. Nature. 2023-12-20 [2023-12-29]. doi:10.1038/d41586-023-03969-5. （原始内容存档于2023-12-28）（英语）.
Decision Memo for Chimeric Antigen Receptor (CAR) T-cell Therapy for Cancers (CAG-00451N). www.cms.gov. [2021-03-22]. （原始内容存档于2021-05-14）（美国英语）.
CAR T-cell Therapy: An Update on Coverage and Reimbursement - Hematology.org. www.hematology.org. [2021-03-22]. （原始内容存档于2022-01-24）（英语）.
Eder M. Which countries is CAR T-cell therapy available in? | SingleUseSupport. 25 November 2021 [13 May 2022]. （原始内容存档于2021-12-06）.
Anvisa aprova produto de terapia avançada para tratamento de câncer. Agência Nacional de Vigilância Sanitária - Anvisa. 2022-02-23 [2022-06-07]. （原始内容存档于2023-12-15）（巴西葡萄牙语）.

worldcat.org

Li, Nan; Ho, Mitchell. Development of Glypican-2 Targeting Single-Domain Antibody CAR T Cells for Neuroblastoma. Single-Domain Antibodies. Methods in Molecular Biology 2446. 2022: 451–468 [2023-10-11]. ISBN 978-1-0716-2074-8. ISSN 1940-6029. PMID 35157288. S2CID 246813053. doi:10.1007/978-1-0716-2075-5_23. （原始内容存档于2023-12-16）.
Li, Nan; Spetz, Madeline R.; Li, Dan; Ho, Mitchell. Advances in immunotherapeutic targets for childhood cancers: A focus on glypican-2 and B7-H3. Pharmacology & Therapeutics. July 2021, 223: 107892. ISSN 1879-016X. PMC 8202769 . PMID 33992682. doi:10.1016/j.pharmthera.2021.107892.
Li, Dan; Lin, Shaoli; Hong, Jessica; Ho, Mitchell. Immunotherapy for hepatobiliary cancers: Emerging targets and translational advances. Advances in Cancer Research. 2022, 156: 415–449 [2023-10-19]. ISBN 9780323983921. ISSN 2162-5557. PMID 35961708. S2CID 246978004. doi:10.1016/bs.acr.2022.01.013. （原始内容存档于2023-12-16）.
Li, Nan; Fu, Haiying; Hewitt, Stephen M.; Dimitrov, Dimiter S.; Ho, Mitchell. Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America. 2017-08-08, 114 (32): E6623–E6631. Bibcode:2017PNAS..114E6623L. ISSN 1091-6490. PMC 5559039 . PMID 28739923. doi:10.1073/pnas.1706055114 .
Li, Nan; Torres, Madeline B.; Spetz, Madeline R.; Wang, Ruixue; Peng, Luyi; Tian, Meijie; Dower, Christopher M.; Nguyen, Rosa; Sun, Ming; Tai, Chin-Hsien; de Val, Natalia; Cachau, Raul; Wu, Xiaolin; Hewitt, Stephen M.; Kaplan, Rosandra N. CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice. Cell Reports. Medicine. 2021-06-15, 2 (6): 100297. ISSN 2666-3791. PMC 8233664 . PMID 34195677. doi:10.1016/j.xcrm.2021.100297.
Berg P, Schönefeld S, Ruppert-Seipp G, Funk MB. Regulatory Measures to Improve the Safety of CAR-T-Cell Treatment. Transfusion Medicine and Hemotherapy. 2022-11-29, 50 (3): 218–225 [2023-11-08]. ISSN 1660-3796. doi:10.1159/000526786 . （原始内容存档于2022-12-09）（英语）.
Li, Nan; Quan, Alex; Li, Dan; Pan, Jiajia; Ren, Hua; Hoeltzel, Gerard; de Val, Natalia; Ashworth, Dana; Ni, Weiming; Zhou, Jing; Mackay, Sean; Hewitt, Stephen M.; Cachau, Raul; Ho, Mitchell. The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer. Nature Communications. 2023-04-08, 14 (1): 1986. Bibcode:2023NatCo..14.1986L. ISSN 2041-1723. PMC 10082787 . PMID 37031249. doi:10.1038/s41467-023-37616-4 （英语）.
Kolluri, Aarti; Li, Dan; Li, Nan; Duan, Zhijian; Roberts, Lewis R.; Ho, Mitchell. Human VH-based chimeric antigen receptor T cells targeting glypican 3 eliminate tumors in preclinical models of HCC. Hepatology Communications. 2023-02-01, 7 (2): e0022. ISSN 2471-254X. PMC 9851680 . PMID 36691969. doi:10.1097/HC9.0000000000000022.
Li, Dan; English, Hejiao; Hong, Jessica; Liang, Tianyuzhou; Merlino, Glenn; Day, Chi-Ping; Ho, Mitchell. A novel PD-L1-targeted shark VNAR single-domain-based CAR-T cell strategy for treating breast cancer and liver cancer. Molecular Therapy: Oncolytics. 2022-03-17, 24: 849–863. ISSN 2372-7705. PMC 8917269 . PMID 35317524. doi:10.1016/j.omto.2022.02.015.
Smith, Tyrel T.; Stephan, Sirkka B.; Moffett, Howell F.; McKnight, Laura E.; Ji, Weihang; Reiman, Diana; Bonagofski, Emmy; Wohlfahrt, Martin E.; Pillai, Smitha P. S.; Stephan, Matthias T. In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers. Nature Nanotechnology. 2017-04-17, 12 (8): 813–820. ISSN 1748-3387. PMC 5646367 . PMID 28416815. doi:10.1038/nnano.2017.57.
Agarwal, Shiwani; Weidner, Tatjana; Thalheimer, Frederic B.; Buchholz, Christian J. In vivo generated human CAR T cells eradicate tumor cells. OncoImmunology. 2019-10-10, 8 (12): e1671761. ISSN 2162-402X. PMC 6844313 . PMID 31741773. doi:10.1080/2162402x.2019.1671761.
Agarwalla, Pritha; Ogunnaike, Edikan A.; Ahn, Sarah; Froehlich, Kristen A.; Jansson, Anton; Ligler, Frances S.; Dotti, Gianpietro; Brudno, Yevgeny. Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells. Nature Biotechnology. 2022-03-24, 40 (8): 1250–1258. ISSN 1087-0156. PMC 9376243 . PMID 35332339. doi:10.1038/s41587-022-01245-x.
Ghassemi, Saba; Durgin, Joseph S.; Nunez-Cruz, Selene; Patel, Jai; Leferovich, John; Pinzone, Marilia; Shen, Feng; Cummins, Katherine D.; Plesa, Gabriela; Cantu, Vito Adrian; Reddy, Shantan; Bushman, Frederic D.; Gill, Saar I.; O'Doherty, Una; O'Connor, Roddy S. Rapid manufacturing of non-activated potent CAR T cells. Nature Biomedical Engineering. February 2022, 6 (2): 118–128. ISSN 2157-846X. PMC 8860360 . PMID 35190680. doi:10.1038/s41551-021-00842-6 （英语）.