弗林蛋白酶 (Chinese Wikipedia)

Analysis of information sources in references of the Wikipedia article "弗林蛋白酶" in Chinese language version.

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24doi.org

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16nih.gov

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11worldcat.org

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3archive.org

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2ensembl.org

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2web.archive.org

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1wikipedia.org

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1semanticscholar.org

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archive.org

Roebroek, A.J.; Schalken, J.A.; Leunissen, J.A.; Onnekink, C.; Bloemers, H.P.; Van de Ven, W.J. Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein.. The EMBO Journal. 1986, 5 (9): 2197–2202. ISSN 0261-4189. doi:10.1002/j.1460-2075.1986.tb04484.x.
van de Ven, Wim J. M.; Voorberg, Jan; Fontijn, Ruud; Pannekoek, Hans; van den Ouweland, Ans M. W.; van Duijnhoven, Hans L. P.; Roebroek, Anton J. M.; Siezen, Roland J. Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes. Molecular Biology Reports. 1990, 14 (4): 265–275. ISSN 0301-4851. doi:10.1007/BF00429896.
Roebroek AJ, Schalken JA, Leunissen JA, Onnekink C, Bloemers HP, Van de Ven WJ. Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein. The EMBO Journal. 1986, 5 (9): 2197–202. PMC 1167100 . PMID 3023061. doi:10.1002/j.1460-2075.1986.tb04484.x.

doi.org

Jaaks P, Bernasconi M. The proprotein convertase furin in tumour progression.. Int J Cancer. 2017, 141 (4): 654–663. PMID 28369813. doi:10.1002/ijc.30714.
Braun E, Sauter D. Furin-mediated protein processing in infectious diseases and cancer.. Clin Transl Immunology. 2019, 8 (8): e1073. PMC 6682551 . PMID 31406574. doi:10.1002/cti2.1073.
Roebroek, A.J.; Schalken, J.A.; Leunissen, J.A.; Onnekink, C.; Bloemers, H.P.; Van de Ven, W.J. Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein.. The EMBO Journal. 1986, 5 (9): 2197–2202. ISSN 0261-4189. doi:10.1002/j.1460-2075.1986.tb04484.x.
van de Ven, Wim J. M.; Voorberg, Jan; Fontijn, Ruud; Pannekoek, Hans; van den Ouweland, Ans M. W.; van Duijnhoven, Hans L. P.; Roebroek, Anton J. M.; Siezen, Roland J. Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes. Molecular Biology Reports. 1990, 14 (4): 265–275. ISSN 0301-4851. doi:10.1007/BF00429896.
Ayoubi, T.A.; Creemers, J.W.; Roebroek, A.J.; Van de Ven, W.J. Expression of the dibasic proprotein processing enzyme furin is directed by multiple promoters.. Journal of Biological Chemistry. 1994, 269 (12): 9298–9303. ISSN 0021-9258. doi:10.1016/S0021-9258(17)37107-7.
Tian S, Huang Q, Fang Y, Wu J. FurinDB: A database of 20-residue furin cleavage site motifs, substrates and their associated drugs.. Int J Mol Sci. 2011, 12 (2): 1060–5. PMC 3083689 . PMID 21541042. doi:10.3390/ijms12021060.
Wise RJ, Barr PJ, Wong PA, Kiefer MC, Brake AJ, Kaufman RJ. Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site. Proceedings of the National Academy of Sciences of the United States of America. 1990, 87 (23): 9378–82. PMC 55168 . PMID 2251280. doi:10.1073/pnas.87.23.9378.
Kiefer MC, Tucker JE, Joh R, Landsberg KE, Saltman D, Barr PJ. Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome 15. DNA and Cell Biology. Dec 1991, 10 (10): 757–69. PMID 1741956. doi:10.1089/dna.1991.10.757.
Roebroek AJ, Schalken JA, Leunissen JA, Onnekink C, Bloemers HP, Van de Ven WJ. Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein. The EMBO Journal. 1986, 5 (9): 2197–202. PMC 1167100 . PMID 3023061. doi:10.1002/j.1460-2075.1986.tb04484.x.
Essalmani, Rachid; Susan-Resiga, Delia; Chamberland, Ann; Abifadel, Marianne; Creemers, John W.; Boileau, Catherine; Seidah, Nabil G.; Prat, Annik. In Vivo Evidence That Furin from Hepatocytes Inactivates PCSK9. Journal of Biological Chemistry. 2011, 286 (6): 4257–4263. ISSN 0021-9258. doi:10.1074/jbc.M110.192104.
Jin, Weijun; Fuki, Ilia V.; Seidah, Nabil G.; Benjannet, Suzanne; Glick, Jane M.; Rader, Daniel J. Proprotein Covertases Are Responsible for Proteolysis and Inactivation of Endothelial Lipase. Journal of Biological Chemistry. 2005, 280 (44): 36551–36559. ISSN 0021-9258. doi:10.1074/jbc.M502264200.
Chen, Y.; Molloy, S. S.; Thomas, L.; Gambee, J.; Bachinger, H. P.; Ferguson, B.; Zonana, J.; Thomas, G.; Morris, N. P. Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia. Proceedings of the National Academy of Sciences. 2001, 98 (13): 7218–7223. ISSN 0027-8424. doi:10.1073/pnas.131076098.
Hallenberger S, Bosch V, Angliker H, Shaw E, Klenk HD, Garten W. Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160. Nature. 1992, 360 (6402): 358–61. PMID 1360148. S2CID 4306605. doi:10.1038/360358a0.
Izaguirre G. The Proteolytic Regulation of Virus Cell Entry by Furin and Other Proprotein Convertases.. Viruses. 2019, 11 (9). PMC 6784293 . PMID 31505793. doi:10.3390/v11090837.
Matsuyama, Shutoku; Shirato, Kazuya; Kawase, Miyuki; Terada, Yutaka; Kawachi, Kengo; Fukushi, Shuetsu; Kamitani, Wataru; Gallagher, Tom. Middle East Respiratory Syndrome Coronavirus Spike Protein Is Not Activated Directly by Cellular Furin during Viral Entry into Target Cells. Journal of Virology. 2018, 92 (19). ISSN 0022-538X. doi:10.1128/JVI.00683-18.
Örd, Mihkel; Faustova, Ilona; Loog, Mart. The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV. Scientific Reports. 2020, 10 (1). ISSN 2045-2322. doi:10.1038/s41598-020-74101-0.
Wu Y, Zhao S. Furin cleavage sites naturally occur in coronaviruses.. Stem Cell Res. 2020, 50: 102115 [2021-06-10]. PMC 7836551 . PMID 33340798. doi:10.1016/j.scr.2020.102115. （原始内容存档于2021-06-10）.
Coutard B, Valle C, de Lamballerie X, Canard B, Seidah NG, Decroly E. The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade. Antiviral Research. February 2020, 176: 104742. PMC 7114094 . PMID 32057769. doi:10.1016/j.antiviral.2020.104742 .
Hoffmann, Markus. A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells. Molecular Cell. 2020, 78 (4): 779–784.e5. PMC 7194065 . PMID 32362314. doi:10.1016/j.molcel.2020.04.022.
Shang, Jian; Wan, Yushun; Luo, Chuming; Ye, Gang; Geng, Qibin; Auerbach, Ashley; Li, Fang. Cell entry mechanisms of SARS-CoV-2. Proceedings of the National Academy of Sciences. 2020, 117 (21): 11727–11734. ISSN 0027-8424. doi:10.1073/pnas.2003138117.
Hartenian, Ella; Nandakumar, Divya; Lari, Azra; Ly, Michael; Tucker, Jessica M.; Glaunsinger, Britt A. The molecular virology of coronaviruses. Journal of Biological Chemistry. 2020, 295 (37): 12910–12934. ISSN 0021-9258. doi:10.1074/jbc.REV120.013930.
Papa G, Mallery DL, Albecka A, Welch LG, Cattin-Ortolá J, Luptak J; et al. Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion.. PLoS Pathog. 2021, 17 (1): e1009246 [2021-06-10]. PMC 7861537 . PMID 33493182. doi:10.1371/journal.ppat.1009246. （原始内容存档于2021-06-10）.
Zhou, Hong; Chen, Xing; Hu, Tao; Li, Juan; Song, Hao; Liu, Yanran; Wang, Peihan; Liu, Di; Yang, Jing; Holmes, Edward C.; Hughes, Alice C.; Bi, Yuhai; Shi, Weifeng. A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein. Current Biology. 2020, 30 (11): 2196–2203.e3. ISSN 0960-9822. doi:10.1016/j.cub.2020.05.023.
Shiryaev SA, Remacle AG, Ratnikov BI, Nelson NA, Savinov AY, Wei G, Bottini M, Rega MF, Parent A, Desjardins R, Fugere M, Day R, Sabet M, Pellecchia M, Liddington RC, Smith JW, Mustelin T, Guiney DG, Lebl M, Strongin AY. Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens. The Journal of Biological Chemistry. Jul 2007, 282 (29): 20847–53. PMID 17537721. doi:10.1074/jbc.M703847200 .

ensembl.org

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000140564 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000030530 - Ensembl, May 2017

nih.gov

ncbi.nlm.nih.gov

Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
Jaaks P, Bernasconi M. The proprotein convertase furin in tumour progression.. Int J Cancer. 2017, 141 (4): 654–663. PMID 28369813. doi:10.1002/ijc.30714.
Braun E, Sauter D. Furin-mediated protein processing in infectious diseases and cancer.. Clin Transl Immunology. 2019, 8 (8): e1073. PMC 6682551 . PMID 31406574. doi:10.1002/cti2.1073.
Tian S, Huang Q, Fang Y, Wu J. FurinDB: A database of 20-residue furin cleavage site motifs, substrates and their associated drugs.. Int J Mol Sci. 2011, 12 (2): 1060–5. PMC 3083689 . PMID 21541042. doi:10.3390/ijms12021060.
Wise RJ, Barr PJ, Wong PA, Kiefer MC, Brake AJ, Kaufman RJ. Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site. Proceedings of the National Academy of Sciences of the United States of America. 1990, 87 (23): 9378–82. PMC 55168 . PMID 2251280. doi:10.1073/pnas.87.23.9378.
Kiefer MC, Tucker JE, Joh R, Landsberg KE, Saltman D, Barr PJ. Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome 15. DNA and Cell Biology. Dec 1991, 10 (10): 757–69. PMID 1741956. doi:10.1089/dna.1991.10.757.
Entrez Gene: FURIN furin (paired basic amino acid cleaving enzyme).
Roebroek AJ, Schalken JA, Leunissen JA, Onnekink C, Bloemers HP, Van de Ven WJ. Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein. The EMBO Journal. 1986, 5 (9): 2197–202. PMC 1167100 . PMID 3023061. doi:10.1002/j.1460-2075.1986.tb04484.x.
Hallenberger S, Bosch V, Angliker H, Shaw E, Klenk HD, Garten W. Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160. Nature. 1992, 360 (6402): 358–61. PMID 1360148. S2CID 4306605. doi:10.1038/360358a0.
Izaguirre G. The Proteolytic Regulation of Virus Cell Entry by Furin and Other Proprotein Convertases.. Viruses. 2019, 11 (9). PMC 6784293 . PMID 31505793. doi:10.3390/v11090837.
Wu Y, Zhao S. Furin cleavage sites naturally occur in coronaviruses.. Stem Cell Res. 2020, 50: 102115 [2021-06-10]. PMC 7836551 . PMID 33340798. doi:10.1016/j.scr.2020.102115. （原始内容存档于2021-06-10）.
Coutard B, Valle C, de Lamballerie X, Canard B, Seidah NG, Decroly E. The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade. Antiviral Research. February 2020, 176: 104742. PMC 7114094 . PMID 32057769. doi:10.1016/j.antiviral.2020.104742 .
Hoffmann, Markus. A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells. Molecular Cell. 2020, 78 (4): 779–784.e5. PMC 7194065 . PMID 32362314. doi:10.1016/j.molcel.2020.04.022.
Papa G, Mallery DL, Albecka A, Welch LG, Cattin-Ortolá J, Luptak J; et al. Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion.. PLoS Pathog. 2021, 17 (1): e1009246 [2021-06-10]. PMC 7861537 . PMID 33493182. doi:10.1371/journal.ppat.1009246. （原始内容存档于2021-06-10）.
Shiryaev SA, Remacle AG, Ratnikov BI, Nelson NA, Savinov AY, Wei G, Bottini M, Rega MF, Parent A, Desjardins R, Fugere M, Day R, Sabet M, Pellecchia M, Liddington RC, Smith JW, Mustelin T, Guiney DG, Lebl M, Strongin AY. Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens. The Journal of Biological Chemistry. Jul 2007, 282 (29): 20847–53. PMID 17537721. doi:10.1074/jbc.M703847200 .

semanticscholar.org

api.semanticscholar.org

Hallenberger S, Bosch V, Angliker H, Shaw E, Klenk HD, Garten W. Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160. Nature. 1992, 360 (6402): 358–61. PMID 1360148. S2CID 4306605. doi:10.1038/360358a0.

web.archive.org

Wu Y, Zhao S. Furin cleavage sites naturally occur in coronaviruses.. Stem Cell Res. 2020, 50: 102115 [2021-06-10]. PMC 7836551 . PMID 33340798. doi:10.1016/j.scr.2020.102115. （原始内容存档于2021-06-10）.
Papa G, Mallery DL, Albecka A, Welch LG, Cattin-Ortolá J, Luptak J; et al. Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion.. PLoS Pathog. 2021, 17 (1): e1009246 [2021-06-10]. PMC 7861537 . PMID 33493182. doi:10.1371/journal.ppat.1009246. （原始内容存档于2021-06-10）.

wikipedia.org

en.wikipedia.org

全稱為枯草桿菌蛋白酶/kexin（英语：kexin）型前体蛋白转化酶（proprotein convertase subtilisin/kexin type），因結構與細菌的枯草桿菌蛋白酶以及酵母菌的kexin蛋白酶相似而得名^[6]。

worldcat.org

Roebroek, A.J.; Schalken, J.A.; Leunissen, J.A.; Onnekink, C.; Bloemers, H.P.; Van de Ven, W.J. Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein.. The EMBO Journal. 1986, 5 (9): 2197–2202. ISSN 0261-4189. doi:10.1002/j.1460-2075.1986.tb04484.x.
van de Ven, Wim J. M.; Voorberg, Jan; Fontijn, Ruud; Pannekoek, Hans; van den Ouweland, Ans M. W.; van Duijnhoven, Hans L. P.; Roebroek, Anton J. M.; Siezen, Roland J. Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes. Molecular Biology Reports. 1990, 14 (4): 265–275. ISSN 0301-4851. doi:10.1007/BF00429896.
Ayoubi, T.A.; Creemers, J.W.; Roebroek, A.J.; Van de Ven, W.J. Expression of the dibasic proprotein processing enzyme furin is directed by multiple promoters.. Journal of Biological Chemistry. 1994, 269 (12): 9298–9303. ISSN 0021-9258. doi:10.1016/S0021-9258(17)37107-7.
Essalmani, Rachid; Susan-Resiga, Delia; Chamberland, Ann; Abifadel, Marianne; Creemers, John W.; Boileau, Catherine; Seidah, Nabil G.; Prat, Annik. In Vivo Evidence That Furin from Hepatocytes Inactivates PCSK9. Journal of Biological Chemistry. 2011, 286 (6): 4257–4263. ISSN 0021-9258. doi:10.1074/jbc.M110.192104.
Jin, Weijun; Fuki, Ilia V.; Seidah, Nabil G.; Benjannet, Suzanne; Glick, Jane M.; Rader, Daniel J. Proprotein Covertases Are Responsible for Proteolysis and Inactivation of Endothelial Lipase. Journal of Biological Chemistry. 2005, 280 (44): 36551–36559. ISSN 0021-9258. doi:10.1074/jbc.M502264200.
Chen, Y.; Molloy, S. S.; Thomas, L.; Gambee, J.; Bachinger, H. P.; Ferguson, B.; Zonana, J.; Thomas, G.; Morris, N. P. Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia. Proceedings of the National Academy of Sciences. 2001, 98 (13): 7218–7223. ISSN 0027-8424. doi:10.1073/pnas.131076098.
Matsuyama, Shutoku; Shirato, Kazuya; Kawase, Miyuki; Terada, Yutaka; Kawachi, Kengo; Fukushi, Shuetsu; Kamitani, Wataru; Gallagher, Tom. Middle East Respiratory Syndrome Coronavirus Spike Protein Is Not Activated Directly by Cellular Furin during Viral Entry into Target Cells. Journal of Virology. 2018, 92 (19). ISSN 0022-538X. doi:10.1128/JVI.00683-18.
Örd, Mihkel; Faustova, Ilona; Loog, Mart. The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV. Scientific Reports. 2020, 10 (1). ISSN 2045-2322. doi:10.1038/s41598-020-74101-0.
Shang, Jian; Wan, Yushun; Luo, Chuming; Ye, Gang; Geng, Qibin; Auerbach, Ashley; Li, Fang. Cell entry mechanisms of SARS-CoV-2. Proceedings of the National Academy of Sciences. 2020, 117 (21): 11727–11734. ISSN 0027-8424. doi:10.1073/pnas.2003138117.
Hartenian, Ella; Nandakumar, Divya; Lari, Azra; Ly, Michael; Tucker, Jessica M.; Glaunsinger, Britt A. The molecular virology of coronaviruses. Journal of Biological Chemistry. 2020, 295 (37): 12910–12934. ISSN 0021-9258. doi:10.1074/jbc.REV120.013930.
Zhou, Hong; Chen, Xing; Hu, Tao; Li, Juan; Song, Hao; Liu, Yanran; Wang, Peihan; Liu, Di; Yang, Jing; Holmes, Edward C.; Hughes, Alice C.; Bi, Yuhai; Shi, Weifeng. A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein. Current Biology. 2020, 30 (11): 2196–2203.e3. ISSN 0960-9822. doi:10.1016/j.cub.2020.05.023.