恩曲他滨/替诺福韦 (Chinese Wikipedia)
Analysis of information sources in references of the Wikipedia article "恩曲他滨/替诺福韦" in Chinese language version.
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aasld.org (Global: low place; Chinese: low place)
- Update on Prevention, Diagnosis, and Treatment of Chronic Hepatitis B: AASLD 2018 Hepatitis B Guidance (PDF). [2019-11-20]. （原始内容 (PDF)存档于2020-01-25）.
- Update on Prevention, Diagnosis, and Treatment of Chronic Hepatitis B: AASLD 2018 Hepatitis B Guidance (PDF). [2019-11-20]. （原始内容 (PDF)存档于2020-01-25）.
aidsmap.com (Global: low place; Chinese: low place)
- PrEP does not raise lipids or alter body fat, safety study finds. [2018-02-16]. （原始内容存档于2018-02-17）.
- European PrEP programs face two big issues: How to get more people coming forward, and how to serve them if they do. 2021-01-27 [2024-08-09]. （原始内容存档于2024-08-18）.
archive.org (Global: 6th place; Chinese: 4th place)
- World Health Organization. Stuart MC, Kouimtzi M, Hill SR , 编. WHO Model Formulary 2008. World Health Organization. 2009: 160. ISBN 9789241547659. hdl:10665/44053.
cdc.gov (Global: 218th place; Chinese: 198th place)
cdc.gov
- PrEP. Centers for Disease Control and Prevention (CDC). 2019-10-17 [2019-10-31]. （原始内容存档于2019-10-31）.
本文含有此來源中屬於公有领域的内容。 - Pre-Exposure Prophylaxis (PrEP). [2015-06-04]. （原始内容存档于2015-06-05）. 本文含有此來源中屬於公有领域的内容。
- Panlilio AL, Cardo DM, Grohskopf LA, Heneine W, Ross CS. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis (PDF). MMWR Recomm Rep. September 2005, 54 (RR-9): 1–17 [2024-08-09]. PMID 16195697. （原始内容存档 (PDF)于2020-07-31）.
stacks.cdc.gov
- Kuhar DT, Henderson DK, Struble KA, Heneine W, Thomas V, Cheever LW, Gomaa A, Panlilio AL. Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis (PDF). Infection Control and Hospital Epidemiology. September 2013, 34 (9): 875–92 [2024-08-09]. PMID 23917901. S2CID 17032413. doi:10.1086/672271. 20711. （原始内容存档 (PDF)于2019-10-30）. 本文含有此來源中屬於公有领域的内容。
clincalc.com (Global: 3,912th place; Chinese: 5,917th place)
- The Top 300 of 2020. ClinCalc. [2022-10-07]. （原始内容存档于2020-03-18）.
- Emtricitabine; Tenofovir Disoproxil - Drug Usage Statistics. ClinCalc. [2022-10-07]. （原始内容存档于2023-10-04）.
cms.gov (Global: low place; Chinese: low place)
- FAQS ABOUT AFFORDABLE CARE ACT IMPLEMENTATION PART 47 (PDF). Centers for Medicare & Medicaid Services. 2021-07-19 [2022-08-04].
doi.org (Global: 2nd place; Chinese: 23rd place)
- Okwundu CI, Uthman OA, Okoromah CA. Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals. Cochrane Database Syst Rev. 2012, 7 (7): CD007189. PMID 22786505. S2CID 35672491. doi:10.1002/14651858.CD007189.pub3.
- Chou R, Evans C, Hoverman A, Sun C, Dana T, Bougatsos C, Grusing S, Korthuis PT. Preexposure Prophylaxis for the Prevention of HIV Infection: Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2019-06-11, 321 (22): 2214–2230. ISSN 0098-7484. PMID 31184746. S2CID 184485546. doi:10.1001/jama.2019.2591
. - Kuhar DT, Henderson DK, Struble KA, Heneine W, Thomas V, Cheever LW, Gomaa A, Panlilio AL. Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis (PDF). Infection Control and Hospital Epidemiology. September 2013, 34 (9): 875–92 [2024-08-09]. PMID 23917901. S2CID 17032413. doi:10.1086/672271. 20711. （原始内容存档 (PDF)于2019-10-30）. 本文含有此來源中屬於公有领域的内容。
- Glidden DV, Mulligan K, McMahan V, Anderson PL, Guanira J, Chariyalertsak S, Buchbinder SP, Bekker LG, Schechter M, Grinsztejn B, Grant RM. Metabolic Effects of Preexposure Prophylaxis With Coformulated Tenofovir Disoproxil Fumarate and Emtricitabine. Clin. Infect. Dis. July 2018, 67 (3): 411–419. PMC 6051460 . PMID 29415175. doi:10.1093/cid/ciy083.* Template:Lay source
- Ramanathan S, Shen G, Cheng A, Kearney BP. Pharmacokinetics of emtricitabine, tenofovir, and GS-9137 following coadministration of emtricitabine/tenofovir disoproxil fumarate and ritonavir-boosted GS-9137. J. Acquir. Immune Defic. Syndr. July 2007, 45 (3): 274–9. PMID 17414929. S2CID 31756102. doi:10.1097/QAI.0b013e318050d88c .
- Keith, Katie. New Guidance On PrEP: Support Services Must Be Covered Without Cost-Sharing | Health Affairs Forefront. Health Affairs Forefront. 2021 [2022-08-04]. doi:10.1377/forefront.20210728.333084 （英语）.
drugs.com (Global: 399th place; Chinese: 208th place)
- Emtricitabine / tenofovir Pregnancy and Breastfeeding Warnings. Drugs.com. 2018-08-01 [2019-10-10]. （原始内容存档于2019-10-10）.
- Truvada. Drugs.com. [2016-12-12]. （原始内容存档于2016-12-20）.
- Generic Truvada Availability. Drugs.com. 2024-07-11 [2024-07-25].
- Emtricitabine / tenofovir Use During Pregnancy. Drugs.com. [2019 -10-23]. （原始内容存档于2019-10-10）.
espacenet.com (Global: 800th place; Chinese: 1,214th place)
worldwide.espacenet.com
- EP0915894B1 - NUCLEOTIDE ANALOGS. Espacenet. [2017-12-13]. （原始内容存档于2019-01-30）.
europa.eu (Global: 68th place; Chinese: 209th place)
ema.europa.eu
- Truvada EPAR. European Medicines Agency. 2005-02-21 [2024-06-13]. （原始内容存档于2024-05-12）.
fiercepharma.com (Global: low place; Chinese: low place)
- U.K. Court invalidates Gilead's Truvada patent extension, allowing PrEP generics. 2018-09-19 [2024-08-09]. （原始内容存档于2023-12-06）.
gilead.com (Global: low place; Chinese: low place)
- Petitions to US Patent and Trademark Office on HIV PrEP Patents. Gilead Sciences (新闻稿). 2019-08-21 [2019-10-29]. （原始内容存档于2019-10-30）.
gov.uk (Global: 432nd place; Chinese: 770th place)
- HIV drug PrEP to be available across England. [2024-08-09]. （原始内容存档于2024-04-10）.
handle.net (Global: 102nd place; Chinese: 492nd place)
hdl.handle.net
- World Health Organization. Stuart MC, Kouimtzi M, Hill SR , 编. WHO Model Formulary 2008. World Health Organization. 2009: 160. ISBN 9789241547659. hdl:10665/44053.
- World Health Organization. World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. 2019. hdl:10665/325771 . WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
healthaffairs.org (Global: low place; Chinese: low place)
- Keith, Katie. New Guidance On PrEP: Support Services Must Be Covered Without Cost-Sharing | Health Affairs Forefront. Health Affairs Forefront. 2021 [2022-08-04]. doi:10.1377/forefront.20210728.333084 （英语）.
irishtimes.com (Global: 266th place; Chinese: 1,051st place)
- Gilead loss of generic HIV drug battle a boost for gay community. The Irish Times. [2018-05-18]. （原始内容存档于2018-05-18）.
- Gilead in row with generics manufacturers over HIV drug in Ireland. The Irish Times. [2017-10-30]. （原始内容存档于2017-11-07）.
iwantprepnow.co.uk (Global: low place; Chinese: low place)
medicalxpress.com (Global: 8,255th place; Chinese: low place)
- EU door opens for generic version of AIDS medicine Truvada. [2024-08-09]. （原始内容存档于2023-12-04）.
medicines.org.uk (Global: 3,823rd place; Chinese: 3,456th place)
- UK label Truvada film-coated tablets. Electronic Medicines Compendium. August 2016. （原始内容存档于2016-12-20）.
nice.org.uk (Global: 3,258th place; Chinese: 2,433rd place)
- Pre-exposure prophylaxis of HIV in adults at high risk: Truvada (emtricitabine/tenofovir disoproxil). 2016-10-05 [2024-08-09]. （原始内容存档于2019-11-02）.
nih.gov (Global: 4th place; Chinese: 5th place)
ncbi.nlm.nih.gov
- Okwundu CI, Uthman OA, Okoromah CA. Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals. Cochrane Database Syst Rev. 2012, 7 (7): CD007189. PMID 22786505. S2CID 35672491. doi:10.1002/14651858.CD007189.pub3.
- Chou R, Evans C, Hoverman A, Sun C, Dana T, Bougatsos C, Grusing S, Korthuis PT. Preexposure Prophylaxis for the Prevention of HIV Infection: Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2019-06-11, 321 (22): 2214–2230. ISSN 0098-7484. PMID 31184746. S2CID 184485546. doi:10.1001/jama.2019.2591 .
- Panlilio AL, Cardo DM, Grohskopf LA, Heneine W, Ross CS. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis (PDF). MMWR Recomm Rep. September 2005, 54 (RR-9): 1–17 [2024-08-09]. PMID 16195697. （原始内容存档 (PDF)于2020-07-31）.
- Kuhar DT, Henderson DK, Struble KA, Heneine W, Thomas V, Cheever LW, Gomaa A, Panlilio AL. Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis (PDF). Infection Control and Hospital Epidemiology. September 2013, 34 (9): 875–92 [2024-08-09]. PMID 23917901. S2CID 17032413. doi:10.1086/672271. 20711. （原始内容存档 (PDF)于2019-10-30）. 本文含有此來源中屬於公有领域的内容。
- Tenofovir. Drugs and Lactation Database (LactMed) (National Library of Medicine (US)). 2006 [2019-10-23]. PMID 30000609. （原始内容存档于2021-02-26）.
- Glidden DV, Mulligan K, McMahan V, Anderson PL, Guanira J, Chariyalertsak S, Buchbinder SP, Bekker LG, Schechter M, Grinsztejn B, Grant RM. Metabolic Effects of Preexposure Prophylaxis With Coformulated Tenofovir Disoproxil Fumarate and Emtricitabine. Clin. Infect. Dis. July 2018, 67 (3): 411–419. PMC 6051460 . PMID 29415175. doi:10.1093/cid/ciy083.* Template:Lay source
- Ramanathan S, Shen G, Cheng A, Kearney BP. Pharmacokinetics of emtricitabine, tenofovir, and GS-9137 following coadministration of emtricitabine/tenofovir disoproxil fumarate and ritonavir-boosted GS-9137. J. Acquir. Immune Defic. Syndr. July 2007, 45 (3): 274–9. PMID 17414929. S2CID 31756102. doi:10.1097/QAI.0b013e318050d88c .
aidsinfo.nih.gov
- Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV (PDF). AIDSinfo Clinical Guidelines. July 2019 [2019-10-30]. （原始内容 (PDF)存档于2016-12-04）.
- Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV (PDF). [2019-10-30]. （原始内容 (PDF)存档于2016-12-02-04）.
- Brief What's New in the Guidelines Perinatal. AIDSinfo. [2019-10-23]. （原始内容存档于2019-10-23）.
- Recommendations for use of antiretroviral drugs in pregnant HIV-1-infected women for maternal health and interventions to reduce perinatal HIV transmission in the United States (PDF). National Institutes of Health (NIH). [2014-10-21]. （原始内容存档 (PDF)于2014-04-12）.
dailymed.nlm.nih.gov
- Truvada- emtricitabine and tenofovir disoproxil fumarate tablet, film coated label. DailyMed. 2018-05-18 [2019-10-31]. （原始内容存档于2019-10-31）.
- DailyMed - XENICAL- orlistat capsule. dailymed.nlm.nih.gov. [2019-10-30]. （原始内容存档于2019-02-27）.
nwsource.com (Global: 907th place; Chinese: 1,343rd place)
seattletimes.nwsource.com
- Perrone, Matthew. FDA approves first pill to help prevent HIV. The Seattle Times. Associated Press. 2012-07-16. （原始内容存档于2012-07-19）.
pharmacy-xl.org (Global: low place; Chinese: low place)
- Generic Sovaldi. [2024-08-09]. （原始内容存档于2024-07-16）.
pharmaphorum.com (Global: low place; Chinese: low place)
- Truvada ruling could allow cheap HIV prevention in the UK -. 2018-09-19 [2024-08-09]. （原始内容存档于2024-04-21）.
reuters.com (Global: 49th place; Chinese: 81st place)
- Blake Brittain. Gilead Sciences prevails in US government lawsuit over HIV drug patents. Reuter. 2023-05-10 [2024-0724]. （原始内容存档于2023-05-20）.
semanticscholar.org (Global: 11th place; Chinese: 332nd place)
api.semanticscholar.org
- Okwundu CI, Uthman OA, Okoromah CA. Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals. Cochrane Database Syst Rev. 2012, 7 (7): CD007189. PMID 22786505. S2CID 35672491. doi:10.1002/14651858.CD007189.pub3.
- Chou R, Evans C, Hoverman A, Sun C, Dana T, Bougatsos C, Grusing S, Korthuis PT. Preexposure Prophylaxis for the Prevention of HIV Infection: Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2019-06-11, 321 (22): 2214–2230. ISSN 0098-7484. PMID 31184746. S2CID 184485546. doi:10.1001/jama.2019.2591 .
- Kuhar DT, Henderson DK, Struble KA, Heneine W, Thomas V, Cheever LW, Gomaa A, Panlilio AL. Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis (PDF). Infection Control and Hospital Epidemiology. September 2013, 34 (9): 875–92 [2024-08-09]. PMID 23917901. S2CID 17032413. doi:10.1086/672271. 20711. （原始内容存档 (PDF)于2019-10-30）. 本文含有此來源中屬於公有领域的内容。
- Ramanathan S, Shen G, Cheng A, Kearney BP. Pharmacokinetics of emtricitabine, tenofovir, and GS-9137 following coadministration of emtricitabine/tenofovir disoproxil fumarate and ritonavir-boosted GS-9137. J. Acquir. Immune Defic. Syndr. July 2007, 45 (3): 274–9. PMID 17414929. S2CID 31756102. doi:10.1097/QAI.0b013e318050d88c .
statnews.com (Global: 8,771st place; Chinese: 9,752nd place)
- Silverman, Ed. Biden administration appeals jury finding in battle over patents for HIV prevention pills. STAT News. 2024-07-08 [2024-07-08]. （原始内容存档于2024-08-02）.
tga.gov.au (Global: 3,984th place; Chinese: 1,603rd place)
- Prescription medicines: registration of new generic medicines and biosimilar medicines, 2017. Therapeutic Goods Administration (TGA). 2022-06-21 [2024-03-30]. （原始内容存档于2023-07-06）.
uptodate.com (Global: 3,771st place; Chinese: 4,225th place)
- Administration of pre-exposure prophylaxis against HIV infection. UpToDate. [2019-10-31]. （原始内容存档于2019-11-01）.
washingtonpost.com (Global: 34th place; Chinese: 129th place)
- Rowland, Christopher. Gilead defied a government HIV patent. The Justice Department has opened a review.. The Washington Post. 2019-04-24 [2019-10-31]. （原始内容存档于2019-11-01）.
- Rowland, Christopher. Gilead files challenge to government patents for HIV prevention pill. The Washington Post. 2019-08-21 [2019-10-29]. （原始内容存档于2019-11-01）.
web.archive.org (Global: 1st place; Chinese: 1st place)
- Emtricitabine / tenofovir Pregnancy and Breastfeeding Warnings. Drugs.com. 2018-08-01 [2019-10-10]. （原始内容存档于2019-10-10）.
- Prescription medicines: registration of new generic medicines and biosimilar medicines, 2017. Therapeutic Goods Administration (TGA). 2022-06-21 [2024-03-30]. （原始内容存档于2023-07-06）.
- Truvada EPAR. European Medicines Agency. 2005-02-21 [2024-06-13]. （原始内容存档于2024-05-12）.
- Truvada. Drugs.com. [2016-12-12]. （原始内容存档于2016-12-20）.
- UK label Truvada film-coated tablets. Electronic Medicines Compendium. August 2016. （原始内容存档于2016-12-20）.
- Truvada- emtricitabine and tenofovir disoproxil fumarate tablet, film coated label. DailyMed. 2018-05-18 [2019-10-31]. （原始内容存档于2019-10-31）.
- The Top 300 of 2020. ClinCalc. [2022-10-07]. （原始内容存档于2020-03-18）.
- Emtricitabine; Tenofovir Disoproxil - Drug Usage Statistics. ClinCalc. [2022-10-07]. （原始内容存档于2023-10-04）.
- Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV (PDF). AIDSinfo Clinical Guidelines. July 2019 [2019-10-30]. （原始内容 (PDF)存档于2016-12-04）.
- PrEP. Centers for Disease Control and Prevention (CDC). 2019-10-17 [2019-10-31]. （原始内容存档于2019-10-31）. 本文含有此來源中屬於公有领域的内容。
- Perrone, Matthew. FDA approves first pill to help prevent HIV. The Seattle Times. Associated Press. 2012-07-16. （原始内容存档于2012-07-19）.
- Pre-Exposure Prophylaxis (PrEP). [2015-06-04]. （原始内容存档于2015-06-05）. 本文含有此來源中屬於公有领域的内容。
- Administration of pre-exposure prophylaxis against HIV infection. UpToDate. [2019-10-31]. （原始内容存档于2019-11-01）.
- Pre-exposure prophylaxis of HIV in adults at high risk: Truvada (emtricitabine/tenofovir disoproxil). 2016-10-05 [2024-08-09]. （原始内容存档于2019-11-02）.
- Panlilio AL, Cardo DM, Grohskopf LA, Heneine W, Ross CS. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis (PDF). MMWR Recomm Rep. September 2005, 54 (RR-9): 1–17 [2024-08-09]. PMID 16195697. （原始内容存档 (PDF)于2020-07-31）.
- Kuhar DT, Henderson DK, Struble KA, Heneine W, Thomas V, Cheever LW, Gomaa A, Panlilio AL. Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis (PDF). Infection Control and Hospital Epidemiology. September 2013, 34 (9): 875–92 [2024-08-09]. PMID 23917901. S2CID 17032413. doi:10.1086/672271. 20711. （原始内容存档 (PDF)于2019-10-30）. 本文含有此來源中屬於公有领域的内容。
- Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV (PDF). [2019-10-30]. （原始内容 (PDF)存档于2016-12-02-04）.
- Update on Prevention, Diagnosis, and Treatment of Chronic Hepatitis B: AASLD 2018 Hepatitis B Guidance (PDF). [2019-11-20]. （原始内容 (PDF)存档于2020-01-25）.
- Update on Prevention, Diagnosis, and Treatment of Chronic Hepatitis B: AASLD 2018 Hepatitis B Guidance (PDF). [2019-11-20]. （原始内容 (PDF)存档于2020-01-25）.
- Brief What's New in the Guidelines Perinatal. AIDSinfo. [2019-10-23]. （原始内容存档于2019-10-23）.
- Recommendations for use of antiretroviral drugs in pregnant HIV-1-infected women for maternal health and interventions to reduce perinatal HIV transmission in the United States (PDF). National Institutes of Health (NIH). [2014-10-21]. （原始内容存档 (PDF)于2014-04-12）.
- Emtricitabine / tenofovir Use During Pregnancy. Drugs.com. [2019 -10-23]. （原始内容存档于2019-10-10）.
- Tenofovir. Drugs and Lactation Database (LactMed) (National Library of Medicine (US)). 2006 [2019-10-23]. PMID 30000609. （原始内容存档于2021-02-26）.
- PrEP does not raise lipids or alter body fat, safety study finds. [2018-02-16]. （原始内容存档于2018-02-17）.
- DailyMed - XENICAL- orlistat capsule. dailymed.nlm.nih.gov. [2019-10-30]. （原始内容存档于2019-02-27）.
- EP0915894B1 - NUCLEOTIDE ANALOGS. Espacenet. [2017-12-13]. （原始内容存档于2019-01-30）.
- U.K. Court invalidates Gilead's Truvada patent extension, allowing PrEP generics. 2018-09-19 [2024-08-09]. （原始内容存档于2023-12-06）.
- Truvada ruling could allow cheap HIV prevention in the UK -. 2018-09-19 [2024-08-09]. （原始内容存档于2024-04-21）.
- EU door opens for generic version of AIDS medicine Truvada. [2024-08-09]. （原始内容存档于2023-12-04）.
- Gilead loss of generic HIV drug battle a boost for gay community. The Irish Times. [2018-05-18]. （原始内容存档于2018-05-18）.
- Gilead in row with generics manufacturers over HIV drug in Ireland. The Irish Times. [2017-10-30]. （原始内容存档于2017-11-07）.
- European PrEP programs face two big issues: How to get more people coming forward, and how to serve them if they do. 2021-01-27 [2024-08-09]. （原始内容存档于2024-08-18）.
- Rowland, Christopher. Gilead defied a government HIV patent. The Justice Department has opened a review.. The Washington Post. 2019-04-24 [2019-10-31]. （原始内容存档于2019-11-01）.
- Rowland, Christopher. Gilead files challenge to government patents for HIV prevention pill. The Washington Post. 2019-08-21 [2019-10-29]. （原始内容存档于2019-11-01）.
- Petitions to US Patent and Trademark Office on HIV PrEP Patents. Gilead Sciences (新闻稿). 2019-08-21 [2019-10-29]. （原始内容存档于2019-10-30）.
- Blake Brittain. Gilead Sciences prevails in US government lawsuit over HIV drug patents. Reuter. 2023-05-10 [2024-0724]. （原始内容存档于2023-05-20）.
- Silverman, Ed. Biden administration appeals jury finding in battle over patents for HIV prevention pills. STAT News. 2024-07-08 [2024-07-08]. （原始内容存档于2024-08-02）.
- HIV drug PrEP to be available across England. [2024-08-09]. （原始内容存档于2024-04-10）.
- Generic Sovaldi. [2024-08-09]. （原始内容存档于2024-07-16）.
worldcat.org (Global: 5th place; Chinese: 12th place)
- Chou R, Evans C, Hoverman A, Sun C, Dana T, Bougatsos C, Grusing S, Korthuis PT. Preexposure Prophylaxis for the Prevention of HIV Infection: Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2019-06-11, 321 (22): 2214–2230. ISSN 0098-7484. PMID 31184746. S2CID 184485546. doi:10.1001/jama.2019.2591 .