An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Nat. Genet. December 1997, 17 (4): 399–403. PMID 9398840. doi:10.1038/ng1297-399.
Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D. Projection of an immunological self shadow within the thymus by the aire protein. Science. November 2002, 298 (5597): 1395–401. PMID 12376594. doi:10.1126/science.1075958.
Liston A, Lesage S, Wilson J, Peltonen L, Goodnow CC. Aire regulates negative selection of organ-specific T cells. Nat. Immunol. April 2003, 4 (4): 350–4. PMID 12612579. doi:10.1038/ni906.
Lindmark E, Chen Y, Georgoudaki AM, Dudziak D, Lindh E, Adams WC, Loré K, Winqvist O, Chambers BJ, Karlsson MC, et al. AIRE expressing marginal zone dendritic cells balances adaptive immunity and T-follicular helper cell recruitment.. Journal of Autoimmunity. 2013, 42: 62–70. PMID 23265639. doi:10.1016/j.jaut.2012.11.004.
Ramsey C, Winqvist O, Puhakka L, Halonen M, Moro A, Kämpe O, Eskelin P, Pelto-Huikko M, Peltonen L. Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. Hum. Mol. Genet. 2002, 11 (4): 397–409. PMID 11854172. doi:10.1093/hmg/11.4.397.
Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Nat. Genet. December 1997, 17 (4): 399–403. PMID 9398840. doi:10.1038/ng1297-399.
Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D. Projection of an immunological self shadow within the thymus by the aire protein. Science. November 2002, 298 (5597): 1395–401. PMID 12376594. doi:10.1126/science.1075958.
Liston A, Lesage S, Wilson J, Peltonen L, Goodnow CC. Aire regulates negative selection of organ-specific T cells. Nat. Immunol. April 2003, 4 (4): 350–4. PMID 12612579. doi:10.1038/ni906.
Ramsey C, Winqvist O, Puhakka L, Halonen M, Moro A, Kämpe O, Eskelin P, Pelto-Huikko M, Peltonen L. Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. Hum. Mol. Genet. 2002, 11 (4): 397–409. PMID 11854172. doi:10.1093/hmg/11.4.397.