(英文)Whitby FG, Masters EI, Kramer L, Knowlton JR, Yao Y, Wang CC, Hill CP. Structural basis for the activation of 20S proteasomes by 11S regulators. Nature. 2000, 408 (6808): 115–120. PMID 11081519.
(英文)Ciehanover A, Hod Y, Hershko A. (1978). A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes. Biochem Biophys Res Commun. 81(4):1100–1105. PMID 666810
(英文)Goldknopf IL, Busch H. (1977). Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24. Proc Natl Acad Sci USA 74(3):864-8. PMID 265581
(英文)Ciechanover A. (2000). Early work on the ubiquitin proteasome system, an interview with Aaron Ciechanover. Cell Death Differ Sep;12(9):1167–77. PMID 16094393
(英文)Hershko A. (2005). Early work on the ubiquitin proteasome system, an interview with Avram Hershko. Cell Death Differ 12, 1158–1161. PMID 16094391
(英文)Kopp F, Steiner R, Dahlmann B, Kuehn L, Reinauer H. (1986). Size and shape of the multicatalytic proteinase from rat skeletal muscle. Biochim Biophys Acta 872(3):253-60. PMID 3524688
(英文)Löwe J, Stock D, Jap B, Zwickl P, Baumeister W, Huber R. (1995). Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 Å resolution. Science 268, 533–539. PMID 7725097
(英文)Wang J, Maldonado MA. (2006). The Ubiquitin-Proteasome System and Its Role in Inflammatory and Autoimmune Diseases. Cell Mol Immunol 3(4): 255. PMID 16978533
(英文)Nandi D, Tahiliani P, Kumar A, Chandu D. (2006). The ubiquitin-proteasome system. J Biosci Mar;31(1):137-55. PMID 16595883
(英文)Heinemeyer W, Fischer M, Krimmer T, Stachon U, Wolf DH. (1997). The Active Sites of the Eukaryotic 20S Proteasome and Their Involvement in Subunit Precursor Processing J Biol Chem 272(40):25200–25209. PMID 9312134
(英文)Liu CW, Li X, Thompson D, Wooding K, Chang TL, Tang Z, Yu H, Thomas PJ, DeMartino GN. (2006). ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome. Mol Cell October 6;24(1):39–50. PMID 17018291
(英文)Lam YA, Lawson TG, Velayutham M, Zweier JL, Pickart CM. (2002). A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal. Nature 416(6882):763-7. PMID 11961560
(英文)Sharon M, Taverner T, Ambroggio XI, Deshaies RJ, Robinson CV. (2006). Structural Organization of the 19S Proteasome Lid: Insights from MS of Intact Complexes. PLoS Biol Aug;4(8):e267. PMID 16869714
(英文)Higashitsuji H, Liu Y, Mayer RJ, Fujita J. (2005). The oncoprotein gankyrin negatively regulates both p53 and RB by enhancing proteasomal degradation. Cell Cycle 4(10):1335–7. PMID 16177571
(英文)Forster A, Masters EI, Whitby FG, Robinson H, Hill CP. (2005). The 1.9 Å Structure of a Proteasome-11S Activator Complex and Implications for Proteasome-PAN/PA700 Interactions. Mol Cell May 27;18(5):589-99. PMID 15916965
(英文)Ortega, J., J. B. Heymann, A. V. Kajava, V. Ustrell, M. Rechsteiner, and A. C. Steven. The axial channel of the 20S proteasome opens upon binding of the PA200 activator. J. Mol. Biol. 2005, 346: 1221–1227. PMID 15713476.
(英文)Ustrell, V., L. Hoffman, G. Pratt, and M. Rechsteiner. PA200, a nuclear proteasome activator involved in DNA repair. EMBO J. 2002, 21: 3516–3525. PMID 12093752.
(英文)Kruger E, Kloetzel PM, Enenkel C. (2001). 20S proteasome biogenesis. Biochimie Mar-Apr;83(3-4):289-93. PMID 11295488
(英文)Witt S, Kwon YD, Sharon M, Felderer K, Beuttler M, Robinson CV, Baumeister W, Jap BK. (2006). Proteasome assembly triggers a switch required for active-site maturation. Structure Jul;14(7):1179–88. PMID 16843899
(英文)Gorbea C, Taillandier D, Rechsteiner M. (1999). Assembly of the regulatory complex of the 26S proteasome. Mol Biol Rep Apr;26(1-2):15-9. PMID 10363641
(英文)Haas AL, Warms JV, Hershko A, Rose IA. Ubiquitin-activating enzyme: Mechanism and role in protein-ubiquitin conjugation. J Biol Chem. 1982 March 10;257(5):2543–8. PMID 6277905
(英文)Thrower JS, Hoffman L, Rechsteiner M, Pickart CM. (2000). Recognition of the polyubiquitin proteolytic signal. EMBO J 19, 94–102. PMID 10619848
(英文)Risseeuw EP, Daskalchuk TE, Banks TW, Liu E, Cotelesage J, Hellmann H, Estelle M, Somers DE, Crosby WL. Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis. Plant J. 2003 Jun;34(6):753-67. PMID 12795696
(英文)Elsasser S, Finley D. (2005). Delivery of ubiquitinated substrates to protein-unfolding machines. Nat Cell Biol 7(8):742-9. PMID 16056265
(英文)Husnjak K, Elsasser S, Zhang N, Chen X, Randles L, Shi Y, Hofmann K, Walters KJ, Finley D, Dikic I. (2008). Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature 22, 481–488. PMID 18497817
(英文)Schreiner P, Chen X, Husnjak K, Randles L, Zhang N, Elsasser S, Finley D, Dikic I, Walters KJ, Groll M. (2008). Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature 22, 548–552. PMID 18497827
(英文)Sharp PM, Li WH. (1987). Ubiquitin genes as a paradigm of concerted evolution of tandem repeats. J Mol Evol 25(1):1432–1432. PMID 3041010
(英文)Zhu Q, Wani G, Wang QE, El-mahdy M, Snapka RM, Wani AA. (2005). Deubiquitination by proteasome is coordinated with substrate translocation for proteolysis in vivo. Exp Cell Res 307(2):436-51. PMID 15950624
(英文)Wenzel T, Baumeister W. (1995). Conformational constraints in protein degradation by the 20S proteasome. Nat Struct Biol 2: 199–204. PMID 7773788
(英文)Smith DM, Kafri G, Cheng Y, Ng D, Walz T, Goldberg AL. (2005). ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins. Mol Cell 20(5):687-98. PMID 16337593
(英文)Smith DM, Benaroudj N, Goldberg A. (2006). Proteasomes and their associated ATPases: a destructive combination. J Struct Biol 156(1):72–83. PMID 16919475
(英文)Hoyt MA, Zich J, Takeuchi J, Zhang M, Govaerts C, Coffino P. (2006). Glycine-alanine repeats impair proper substrate unfolding by the proteasome. EMBO J 25(8):1720–9. PMID 16601692
(英文)Zhang M, Coffino P. (2004). Repeat sequence of Epstein-Barr virus-encoded nuclear antigen 1 protein interrupts proteasome substrate processing. J Biol Chem 279(10):8635–41. PMID 14688254
(英文)Voges D, Zwickl P, Baumeister W. (1999). The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem 68: 1015–1068. PMID 10872471
(英文)Rape M, Jentsch S. (2002). Taking a bite: proteasomal protein processing. Nat Cell Biol 4(5):E113-6. PMID 11988749
(英文)Rape M, Jentsch S. (2004). Productive RUPture: activation of transcription factors by proteasomal processing. Biochim Biophys Acta 1695(1-3):209-13. PMID 15571816
(英文)Asher G, Reuven N, Shaul Y. (2006). 20S proteasomes and protein degradation "by default". Bioessays 28(8):844-9. PMID 16927316
(英文)Zhang M, Pickart CM, Coffino P. (2003). Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate. EMBO J 22(7):1488–96. PMID 12660156
(英文)Asher G, Shaul Y. (2005). p53 proteasomal degradation: poly-ubiquitination is not the whole story. Cell Cycle 4(8):1015–8. PMID 16082197
(英文)Shringarpure R, Grune T, Mehlhase J, Davies KJ. (2003). Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome. J Biol Chem 278(1):311-8. PMID 12401807
(英文)Gille C, Goedel A, Schloetelburg C, Preißner R, Kloetzel PM, Gobel UB, Frommell C. (2003). A Comprehensive View on Proteasomal Sequences: Implications for the Evolution of the Proteasome. J Mol Biol 326: 1437–1448. PMID 12595256
(英文)Bochtler M, Ditzel L, Groll M, Hartmann C, Huber R. (1999). The proteasome. Annu. Rev. Biophys. Biomol. Struct. 28: 295–317. PMID 10410804
(英文)Chesnel F, Bazile F, Pascal A, Kubiak JZ. (2006). Cyclin B dissociation from CDK1 precedes its degradation upon MPF inactivation in mitotic extracts of Xenopus laevis embryos. Cell Cycle 5(15):1687–98. PMID 16921258
(英文)Havens CG, Ho A, Yoshioka N, Dowdy SF. (2006). Regulation of late G1/S phase transition and APC Cdh1 by reactive oxygen species. Mol Cell Biol 26(12):4701–11. PMID 16738333
(英文)Bashir T, Dorrello NV, Amador V, Guardavaccaro D, Pagano M. (2004). Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase. Nature 428(6979):190-3. PMID 15014502
(英文)Dharmasiri S, Estelle M. (2002). The role of regulated protein degradation in auxin response. Plant Mol Biol 49(3-4):401-9. PMID 12036263
(英文)Weijers D, Benkova E, Jager KE, Schlereth A, Hamann T, Kientz M, Wilmoth JC, Reed JW, Jurgens G. (2005). Developmental specificity of auxin response by pairs of ARF and Aux/IAA transcriptional regulators. EMBO J 24(10):1874–85. PMID 15889151
(英文)Haas AL, Baboshina O, Williams B and Schwartz LM (1995) Coordinated induction of the ubiquitin conjugation pathway accompanies the developmentally programmed death of insect skeletal muscle. J. Biol. Chem. 270: 9407–9412. PMID 7721865
(英文)Schwartz LM, Myer A, Kosz L, Engelstein M and Maier C. (1990) Activation of polyubiquitin gene expression during developmentally programmed cell death. Neuron 5: 411–419. PMID 2169771
(英文)Low P, Bussell K, Dawson SP, Billett MA, Mayer RJ and Reynolds SE (1997) Expression of a 26S proteasome ATPase subunit, MS73, in muscles that undergo developmentally programmed cell death, and its control by ecdysteroid hormones in the insect Manduca sexta. FEBS Lett. 400: 345–349. PMID 9009228
(英文)Pitzer F, Dantes A, Fuchs T, Baumeister W, Amsterdam A (1996) Removal of proteasomes from the nucleus and their accumulation in apoptotic blebs during programmed cell death. FEBS Lett. 394: 47–50. PMID 8925925
(英文)Orlowski RZ. (1999). The role of the ubiquitin-proteasome pathway in apoptosis. Cell Death Differ 6: 303–313. PMID 10381632
(英文)Garrido C, Brunet M, Didelot C, Zermati Y, Schmitt E, Kroemer G. (2006). Heat Shock Proteins 27 and 70: Anti-Apoptotic Proteins with Tumorigenic Properties. Cell Cycle 5(22). PMID 17106261
(英文)Park SH, Bolender N, Eisele F, Kostova Z, Takeuchi J, Coffino P, Wolf DH. (2006). The Cytoplasmic Hsp70 Chaperone Machinery Subjects Misfolded and ER Import Incompetent Proteins to Degradation via the Ubiquitin-Proteasome System. Mol Biol Cell Epub. PMID 17065559
(英文)Dai Q, Qian SB, Li HH, McDonough H, Borchers C, Huang D, Takayama S, Younger JM, Ren HY, Cyr DM, Patterson C. (2005). Regulation of the cytoplasmic quality control protein degradation pathway by BAG2. J Biol Chem 280(46):38673-81. PMID 16169850
(英文)Bader N, Grune T. (2006). Protein oxidation and proteolysis. Biol Chem 387(10-11):1351–5. PMID 17081106
(英文)Davies KJ. (2003). Degradation of oxidized proteins by the 20S proteasome. Biochimie 83(3-4):301-10. PMID 11295490
(英文)McNaught KS, Jackson T, JnoBaptiste R, Kapustin A, Olanow CW. (2006). Proteasomal dysfunction in sporadic Parkinson's disease. Neurology 66(10 Suppl 4):S37–49. PMID 16717251
(英文)Sharma N, Brandis KA, Herrera SK, Johnson BE, Vaidya T, Shrestha R, Debburman SK. (2006). Alpha-Synuclein budding yeast model: toxicity enhanced by impaired proteasome and oxidative stress. J Mol Neurosci 28(2):161-78. PMID 16679556
(英文)Murata S, Sasaki K, Kishimoto T, Niwa S, Hayashi H, Takahama Y, Tanaka K. Regulation of CD8+ T cell development by thymus-specific proteasomes. Science: 1349–1353. PMID 17540904.
(英文)Adams J, Palombella VJ, Sausville EA, Johnson J, Destree A, Lazarus DD, Maas J, Pien CS, Prakash S, Elliott PJ. (1999). Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res 59(11):2615–22. PMID 10363983
(英文)Fisher RI, Bernstein SH, Kahl BS, Djulbegovic B, Robertson MJ, de Vos S, Epner E, Krishnan A, Leonard JP, Lonial S, Stadtmauer EA, O'Connor OA, Shi H, Boral AL, Goy A. (2006). Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol 24(30):4867–74. PMID 17001068
(英文)Jakob C, Egerer K, Liebisch P, Turkmen S, Zavrski I, Kuckelkorn U, Heider U, Kaiser M, Fleissner C, Sterz J, Kleeberg L, Feist E, Burmester GR, Kloetzel PM, Sezer O. (2006). Circulating proteasome levels are an independent prognostic factor for survival in multiple myeloma. Blood Epub. PMID 17095627
(英文)Shah SA, Potter MW, McDade TP, Ricciardi R, Perugini RA, Elliott PJ, Adams J, Callery MP. (2001). 26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer. J Cell Biochem 82(1):110-22. PMID 11400168
(英文)Nawrocki ST, Sweeney-Gotsch B, Takamori R, McConkey DJ. (2004). The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts. Mol Cancer Ther 3(1):59–70. PMID 14749476
(英文)Schenkein D. (2002). Proteasome inhibitors in the treatment of B-cell malignancies. Clin Lymphoma 3(1):49–55. PMID 12141956
(英文)O'Connor OA, Wright J, Moskowitz C, Muzzy J, MacGregor-Cortelli B, Stubblefield M, Straus D, Portlock C, Hamlin P, Choi E, Dumetrescu O, Esseltine D, Trehu E, Adams J, Schenkein D, Zelenetz AD. (2005). Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma. J Clin Oncol 23(4):676-84. PMID 15613699
(英文)Schmidtke G, Holzhutter HG, Bogyo M, Kairies N, Groll M, de Giuli R, Emch S, Groettrup M. (1999). How an inhibitor of the HIV-I protease modulates proteasome activity. J Biol Chem 274(50):35734-40. PMID 10585454
(英文)Laurent N, de Bouard S, Guillamo JS, Christov C, Zini R, Jouault H, Andre P, Lotteau V, Peschanski M. (2004). Effects of the proteasome inhibitor ritonavir on glioma growth in vitro and in vivo. Mol Cancer Ther 3(2):129-36. PMID 14985453
(英文)Zollner TM, Podda M, Pien C, Elliott PJ, Kaufmann R, Boehncke WH. (2002). Proteasome inhibition reduces superantigenmediated T cell activation and the severity of psoriasis in a SCID-hu model. J Clin Invest. 109:671–679. PMID 11877475
(英文)Elliott PJ, Pien CS, McCormack TA, Chapman ID, Adams J. (1999). Proteasome inhibition: A novel mechanism to combat asthma. J Allergy Clin Immunol. 104:294–300. PMID 10452747
(英文)Verdoes M, Florea BI, Menendez-Benito V, Maynard CJ, Witte MD, van der Linden WA, van den Nieuwendijk AM, Hofmann T, Berkers CR, van Leeuwen FW, Groothuis TA, Leeuwenburgh MA, Ovaa H, Neefjes JJ, Filippov DV, van der Marel GA, Dantuma NP, Overkleeft HS. (2006). A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. Chem Biol 13(11):1217–26. PMID 17114003