Nahmias Y, Schwartz RE, Hu WS, Verfaillie CM, Odde DJ. Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro. Tissue Engineering. June 2006, 12 (6): 1627–38. PMID 16846358. doi:10.1089/ten.2006.12.1627.
Peng H, Poovaiah N, Forrester M, Cochran E, Wang Q. Ex Vivo Culture of Primary Intestinal Stem Cells in Collagen Gels and Foams. ACS Biomaterials Science & Engineering. 2014 Dec 2;1(1):37–42. https://doi.org/10.1021/ab500041d. PMID: 33435081.
Peng H, Wang C, Xu X, Yu C, Wang Q. An intestinal Trojan horse for gene delivery. Nanoscale. 2015 Jan 6;7(10):4354–4360. https://doi.org/10.1039/C4NR06377E. PMID: 25619169.
Yui, S., Nakamura, T., Sato, T. et al. Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell. Nature Medicine 18, 618–623 (2012). https://doi.org/10.1038/nm.2695
Huch, M., Dorrell, C., Boj, S. et al. In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. Nature 494, 247–250 (2013). https://doi.org/10.1038/nature11826
Takebe T, Enomura M, Yoshizawa E, Kimura M, Koike H, Ueno Y, Matsuzaki T, Yamazaki T, Toyohara T, Osafune K, Nakauchi H, Yoshikawa HY, Taniguchi H. Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation. Cell Stem Cell. May 2015, 16 (5): 556–65. PMID 25891906. doi:10.1016/j.stem.2015.03.004.
Lavazza A, Massimini M. Cerebral organoids: ethical issues and consciousness assessment. Journal of Medical Ethics. September 2018, 44 (9): 606–610. PMID 29491041. doi:10.1136/medethics-2017-104555.
Cai T, Qi Y, Jergens A, Wannemuehler M, Barrett TA, Wang Q. Effects of six common dietary nutrients on murine intestinal organoid growth. PLoS One. 2018 Feb 1;13(2):e0191517. https://doi.org/10.1371/journal.pone.0191517. PMID: 29389993; PMCID: PMC5794098.
Qi Y, Lohman J, Bratlie KM, Peroutka-Bigus N, Bellaire B, Wannemuehler M, Yoon KJ, Barrett TA, Wang Q. Vitamin C and B3 as new biomaterials to alter intestinal stem cells. Journal of Biomedical Materials Research Part A. 2019 Sep;107(9):1886–1897. https://doi.org/10.1002/jbm.a.36715. Epub 2019 May 23. PMID: 31071241; PMCID: PMC6626554.
Davoudi Z, Peroutka-Bigus N, Bellaire B, Wannemuehler M, Barrett TA, Narasimhan B, Wang Q. Intestinal organoids containing poly(lactic-co-glycolic acid) nanoparticles for the treatment of inflammatory bowel diseases. Journal of Biomedical Materials Research Part A. 2018 Apr;106(4):876–886. https://doi.org/10.1002/jbm.a.36305. Epub 2017 Dec 21. PMID: 29226615; PMCID: PMC5826879.
Davoudi Z, Peroutka-Bigus N, Bellaire B, Jergens A, Wannemuehler M, Wang Q. Gut Organoid as a New Platform to Study Alginate and Chitosan Mediated PLGA Nanoparticles for Drug Delivery. Marine Drugs. 2021 May 20;19(5):282. https://doi.org/10.3390/md19050282. PMID: 34065505; PMCID: PMC8161322.
Qi Y, Shi E, Peroutka-Bigus N, Bellaire B, Wannemuehler M, Jergens A, Barrett T, Wu Y, Wang Q. Ex Vivo Study of Telluride Nanowires in Minigut. Journal of Biomedical Nanotechnology. 2018 May 1;14(5):978–986. https://doi.org/10.1166/jbn.2018.2578. PMID: 29883567
Reding B, Carter P, Qi Y, Li Z, Wu Y, Wannemuehler M, Bratlie KM, Wang Q. Manipulate intestinal organoids with niobium carbide nanosheets. Journal of Biomedical Materials Research Part A. 2021 Apr;109(4):479–487. https://doi.org/10.1002/jbm.a.37032. Epub 2020 Jun 17. PMID: 32506610.
Sun L, Rollins D, Qi Y, Fredericks J, Mansell TJ, Jergens A, Phillips GJ, Wannemuehler M, Wang Q. TNFα regulates intestinal organoids from mice with both defined and conventional microbiota. International Journal of Biological Macromolecules. 2020 Dec 1;164:548–556. https://doi.org/10.1016/j.ijbiomac.2020.07.176. Epub 2020 Jul 18. PMID: 32693143; PMCID: PMC7657954.
Tong T, Qi Y, Rollins D, Bussiere LD, Dhar D, Miller CL, Yu C, Wang Q. Rational design of oral drugs targeting mucosa delivery with gut organoid platforms. Bioactive Materials. 2023; 30: 116–128. https://doi.org/10.1016/j.bioactmat.2023.07.014. PMID 37560199.
Davoudi Z, Atherly T, Borcherding DC, Jergens AE, Wannemuehler M, Barrett TA, Wang Q. Study Transportation of Drugs within Newly Established Murine Colon Organoid Systems. Advanced Biology. 2023; e2300103. https://doi.org/10.1002/adbi.202300103. PMID 37607116.
Lindemans C, Mertelsmann A, Dudakov JA, Velardi E, Hua G, O'Connor M, Kolesnick R, van den Brink MR, Hanash AM. IL-22 Administration Protects Intestinal Stem Cells from Gvhd. Biology of Blood and Marrow Transplantation. 2014, 20 (2): S53–S54. doi:10.1016/j.bbmt.2013.12.056.
Tong T, Qi Y, Bussiere LD, Wannemuehler M, Miller CL, Wang Q, Yu C . Transport of artificial virus-like nanocarriers through intestinal monolayers via microfold cells. Nanoscale. 2020 Aug 14;12(30):16339-16347. https://doi.org/10.1039/D0NR03680C. Epub 2020 Jul 29. PMID 32725029.
Barker N, Huch M, Kujala P, van de Wetering M, Snippert HJ, van Es JH, Sato T, Stange DE, Begthel H, van den Born M, Danenberg E, van den Brink S, Korving J, Abo A, Peters PJ, Wright N, Poulsom R, Clevers H. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell. January 2010, 6 (1): 25–36. PMID 20085740. doi:10.1016/j.stem.2009.11.013.
Martin A, Barbesino G, Davies TF. T-cell receptors and autoimmune thyroid disease—signposts for T-cell-antigen driven diseases. International Reviews of Immunology. 1999, 18 (1–2): 111–40. PMID 10614741. doi:10.3109/08830189909043021.
Takasato M, Er PX, Chiu HS, Maier B, Baillie GJ, Ferguson C, Parton RG, Wolvetang EJ, Roost MS, Chuva de Sousa Lopes SM, Little MH. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature. October 2015, 526 (7574): 564–8. Bibcode:2015Natur.526..564T. PMID 26444236. S2CID 4443766. doi:10.1038/nature15695.
Lee EJ, Kim DE, Azeloglu EU, Costa KD. Engineered cardiac organoid chambers: toward a functional biological model ventricle. Tissue Engineering. Part A. February 2008, 14 (2): 215–25. PMID 18333774. doi:10.1089/tea.2007.0351.
Engle SJ, Blaha L, Kleiman RJ. Best Practices for Translational Disease Modeling Using Human iPSC-Derived Neurons. Neuron. November 2018, 100 (4): 783–797. PMID 30465765. doi:10.1016/j.neuron.2018.10.033.
Dekkers JF, Wiegerinck CL, de Jonge HR, Bronsveld I, Janssens HM, de Winter-de Groot KM, Brandsma AM, de Jong NW, Bijvelds MJ, Scholte BJ, Nieuwenhuis EE, van den Brink S, Clevers H, van der Ent CK, Middendorp S, Beekman JM. A functional CFTR assay using primary cystic fibrosis intestinal organoids. Nature Medicine. July 2013, 19 (7): 939–45. PMID 23727931. S2CID 5369669. doi:10.1038/nm.3201.
Dekkers JF, Berkers G, Kruisselbrink E, Vonk A, de Jonge HR, Janssens HM, Bronsveld I, van de Graaf EA, Nieuwenhuis EE, Houwen RH, Vleggaar FP, Escher JC, de Rijke YB, Majoor CJ, Heijerman HG, de Winter-de Groot KM, Clevers H, van der Ent CK, Beekman JM. Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis. Science Translational Medicine. June 2016, 8 (344): 344ra84. PMID 27334259. S2CID 19462535. doi:10.1126/scitranslmed.aad8278.
Schwank G, Koo BK, Sasselli V, Dekkers JF, Heo I, Demircan T, Sasaki N, Boymans S, Cuppen E, van der Ent CK, Nieuwenhuis EE, Beekman JM, Clevers H. Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell. December 2013, 13 (6): 653–8. PMID 24315439. doi:10.1016/j.stem.2013.11.002.
Takasato M, Er PX, Chiu HS, Maier B, Baillie GJ, Ferguson C, Parton RG, Wolvetang EJ, Roost MS, Chuva de Sousa Lopes SM, Little MH. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature. October 2015, 526 (7574): 564–8. Bibcode:2015Natur.526..564T. PMID 26444236. S2CID 4443766. doi:10.1038/nature15695.
Nahmias Y, Schwartz RE, Hu WS, Verfaillie CM, Odde DJ. Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro. Tissue Engineering. June 2006, 12 (6): 1627–38. PMID 16846358. doi:10.1089/ten.2006.12.1627.
Takebe T, Enomura M, Yoshizawa E, Kimura M, Koike H, Ueno Y, Matsuzaki T, Yamazaki T, Toyohara T, Osafune K, Nakauchi H, Yoshikawa HY, Taniguchi H. Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation. Cell Stem Cell. May 2015, 16 (5): 556–65. PMID 25891906. doi:10.1016/j.stem.2015.03.004.
Lavazza A, Massimini M. Cerebral organoids: ethical issues and consciousness assessment. Journal of Medical Ethics. September 2018, 44 (9): 606–610. PMID 29491041. doi:10.1136/medethics-2017-104555.
Tong T, Qi Y, Rollins D, Bussiere LD, Dhar D, Miller CL, Yu C, Wang Q. Rational design of oral drugs targeting mucosa delivery with gut organoid platforms. Bioactive Materials. 2023; 30: 116–128. https://doi.org/10.1016/j.bioactmat.2023.07.014. PMID 37560199.
Davoudi Z, Atherly T, Borcherding DC, Jergens AE, Wannemuehler M, Barrett TA, Wang Q. Study Transportation of Drugs within Newly Established Murine Colon Organoid Systems. Advanced Biology. 2023; e2300103. https://doi.org/10.1002/adbi.202300103. PMID 37607116.
Tong T, Qi Y, Bussiere LD, Wannemuehler M, Miller CL, Wang Q, Yu C . Transport of artificial virus-like nanocarriers through intestinal monolayers via microfold cells. Nanoscale. 2020 Aug 14;12(30):16339-16347. https://doi.org/10.1039/D0NR03680C. Epub 2020 Jul 29. PMID 32725029.
Barker N, Huch M, Kujala P, van de Wetering M, Snippert HJ, van Es JH, Sato T, Stange DE, Begthel H, van den Born M, Danenberg E, van den Brink S, Korving J, Abo A, Peters PJ, Wright N, Poulsom R, Clevers H. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell. January 2010, 6 (1): 25–36. PMID 20085740. doi:10.1016/j.stem.2009.11.013.
Martin A, Barbesino G, Davies TF. T-cell receptors and autoimmune thyroid disease—signposts for T-cell-antigen driven diseases. International Reviews of Immunology. 1999, 18 (1–2): 111–40. PMID 10614741. doi:10.3109/08830189909043021.
Takasato M, Er PX, Chiu HS, Maier B, Baillie GJ, Ferguson C, Parton RG, Wolvetang EJ, Roost MS, Chuva de Sousa Lopes SM, Little MH. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature. October 2015, 526 (7574): 564–8. Bibcode:2015Natur.526..564T. PMID 26444236. S2CID 4443766. doi:10.1038/nature15695.
Lee EJ, Kim DE, Azeloglu EU, Costa KD. Engineered cardiac organoid chambers: toward a functional biological model ventricle. Tissue Engineering. Part A. February 2008, 14 (2): 215–25. PMID 18333774. doi:10.1089/tea.2007.0351.
Engle SJ, Blaha L, Kleiman RJ. Best Practices for Translational Disease Modeling Using Human iPSC-Derived Neurons. Neuron. November 2018, 100 (4): 783–797. PMID 30465765. doi:10.1016/j.neuron.2018.10.033.
Dekkers JF, Wiegerinck CL, de Jonge HR, Bronsveld I, Janssens HM, de Winter-de Groot KM, Brandsma AM, de Jong NW, Bijvelds MJ, Scholte BJ, Nieuwenhuis EE, van den Brink S, Clevers H, van der Ent CK, Middendorp S, Beekman JM. A functional CFTR assay using primary cystic fibrosis intestinal organoids. Nature Medicine. July 2013, 19 (7): 939–45. PMID 23727931. S2CID 5369669. doi:10.1038/nm.3201.
Dekkers JF, Berkers G, Kruisselbrink E, Vonk A, de Jonge HR, Janssens HM, Bronsveld I, van de Graaf EA, Nieuwenhuis EE, Houwen RH, Vleggaar FP, Escher JC, de Rijke YB, Majoor CJ, Heijerman HG, de Winter-de Groot KM, Clevers H, van der Ent CK, Beekman JM. Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis. Science Translational Medicine. June 2016, 8 (344): 344ra84. PMID 27334259. S2CID 19462535. doi:10.1126/scitranslmed.aad8278.
Schwank G, Koo BK, Sasselli V, Dekkers JF, Heo I, Demircan T, Sasaki N, Boymans S, Cuppen E, van der Ent CK, Nieuwenhuis EE, Beekman JM, Clevers H. Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell. December 2013, 13 (6): 653–8. PMID 24315439. doi:10.1016/j.stem.2013.11.002.
Takasato M, Er PX, Chiu HS, Maier B, Baillie GJ, Ferguson C, Parton RG, Wolvetang EJ, Roost MS, Chuva de Sousa Lopes SM, Little MH. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature. October 2015, 526 (7574): 564–8. Bibcode:2015Natur.526..564T. PMID 26444236. S2CID 4443766. doi:10.1038/nature15695.
Dekkers JF, Wiegerinck CL, de Jonge HR, Bronsveld I, Janssens HM, de Winter-de Groot KM, Brandsma AM, de Jong NW, Bijvelds MJ, Scholte BJ, Nieuwenhuis EE, van den Brink S, Clevers H, van der Ent CK, Middendorp S, Beekman JM. A functional CFTR assay using primary cystic fibrosis intestinal organoids. Nature Medicine. July 2013, 19 (7): 939–45. PMID 23727931. S2CID 5369669. doi:10.1038/nm.3201.
Dekkers JF, Berkers G, Kruisselbrink E, Vonk A, de Jonge HR, Janssens HM, Bronsveld I, van de Graaf EA, Nieuwenhuis EE, Houwen RH, Vleggaar FP, Escher JC, de Rijke YB, Majoor CJ, Heijerman HG, de Winter-de Groot KM, Clevers H, van der Ent CK, Beekman JM. Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis. Science Translational Medicine. June 2016, 8 (344): 344ra84. PMID 27334259. S2CID 19462535. doi:10.1126/scitranslmed.aad8278.