Partition coefficient (English Wikipedia)

Collander R, Lindholm M, Haug CM, Stene J, Sörensen NA (1951). "The partition of organic compounds. between higher alcohols and water" (PDF). Acta Chem. Scand. 5: 774–780. doi:10.3891/acta.chem.scand.05-0774 (inactive 6 September 2025).{{cite journal}}: CS1 maint: DOI inactive as of September 2025 (link)

adsabs.harvard.edu (Global: 14^th place; English: 9^th place)

ui.adsabs.harvard.edu

Sangster J (1989). "Octanol–Water Partition Coefficients of Simple Organic Compounds" (PDF). Journal of Physical and Chemical Reference Data. 18 (3): 1111–1227. Bibcode:1989JPCRD..18.1111S. doi:10.1063/1.555833. Archived from the original (PDF) on 2016-03-04. Retrieved 2017-07-13.
Mannhold R, Poda GI, Ostermann C, Tetko IV (March 2009). "Calculation of molecular lipophilicity: State-of-the-art and comparison of log P methods on more than 96,000 compounds". Journal of Pharmaceutical Sciences. 98 (3): 861–93. Bibcode:2009JPhmS..98..861M. doi:10.1002/jps.21494. PMID 18683876. S2CID 9595034.
Leeson PD, Springthorpe B (November 2007). "The influence of drug-like concepts on decision-making in medicinal chemistry". Nature Reviews. Drug Discovery. 6 (11): 881–90. Bibcode:2007NRvDD...6..881L. doi:10.1038/nrd2445. PMID 17971784. S2CID 205476574.
Eisenberg D, McLachlan AD (1986). "Solvation energy in protein folding and binding". Nature. 319 (6050): 199–203. Bibcode:1986Natur.319..199E. doi:10.1038/319199a0. PMID 3945310. S2CID 21867582.
Miyamoto S, Kollman PA (September 1993). "What determines the strength of noncovalent association of ligands to proteins in aqueous solution?". Proceedings of the National Academy of Sciences of the United States of America. 90 (18): 8402–6. Bibcode:1993PNAS...90.8402M. doi:10.1073/pnas.90.18.8402. PMC 47364. PMID 8378312.
Valkó K (May 2004). "Application of high-performance liquid chromatography based measurements of lipophilicity to model biological distribution". Journal of Chromatography A. 1037 (1–2): 299–310. Bibcode:2004JChA.1037..299V. doi:10.1016/j.chroma.2003.10.084. PMID 15214672.
Karpińska, Aneta; Pilz, Marta; Buczkowska, Joanna; Żuk, Paweł J.; Kucharska, Karolina; Magiera, Gaweł; Kwapiszewska, Karina; Hołyst, Robert (2021). "Quantitative analysis of biochemical processes in living cells at a single-molecule level: a case of olaparib–PARP1 (DNA repair protein) interactions" (PDF). Analyst. 146 (23): 7131–7143. Bibcode:2021Ana...146.7131K. doi:10.1039/D1AN01769A. PMID 34726203. S2CID 240110114.
Karpinska, Aneta; Magiera, Gaweł; Kwapiszewska, Karina; Hołyst, Robert (2023). "Cellular Uptake of Bevacizumab in Cervical and Breast Cancer Cells Revealed by Single-Molecule Spectroscopy". J. Phys. Chem. Lett. 14 (5): 1272–1278. Bibcode:2023JPCL...14.1272K. doi:10.1021/acs.jpclett.2c03590. PMC 9923738. PMID 36719904. S2CID 256415374.
Judson R, Richard A, Dix DJ, Houck K, Martin M, Kavlock R, Dellarco V, Henry T, Holderman T, Sayre P, Tan S, Carpenter T, Smith E (May 2009). "The toxicity data landscape for environmental chemicals". Environmental Health Perspectives. 117 (5): 685–95. Bibcode:2009EnvHP.117..685J. doi:10.1289/ehp.0800168. PMC 2685828. PMID 19479008.
Ghose AK, Viswanadhan VN, Wendoloski JJ (1998). "Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragmental Methods: An Analysis of AlogP and ClogP Methods". Journal of Physical Chemistry A. 102 (21): 3762–3772. Bibcode:1998JPCA..102.3762G. doi:10.1021/jp980230o.
Pinsuwan S, Li A, Yalkowsky SH (May 1995). "Correlation of Octanol/Water Solubility Ratios and Partition Coefficients". Journal of Chemical & Engineering Data. 40 (3): 623–626. Bibcode:1995JCED...40..623P. doi:10.1021/je00019a019.
Skyner RE, McDonagh JL, Groom CR, van Mourik T, Mitchell JB (March 2015). "A review of methods for the calculation of solution free energies and the modelling of systems in solution" (PDF). Physical Chemistry Chemical Physics. 17 (9): 6174–91. Bibcode:2015PCCP...17.6174S. doi:10.1039/c5cp00288e. PMID 25660403.
Hodges G, Eadsforth C, Bossuyt B, Bouvy A, Enrici MH, Geurts M, et al. (2019). "A comparison of log Kow (n-octanol–water partition coefficient) values for non-ionic, anionic, cationic and amphoteric surfactants determined using predictions and experimental methods". Environmental Sciences Europe. 31 (1) 1. Bibcode:2019ESEur..31....1H. doi:10.1186/s12302-018-0176-7.
Hendriks AJ, van der Linde A, Cornelissen G, Sijm DT (July 2001). "The power of size. 1. Rate constants and equilibrium ratios for accumulation of organic substances related to octanol-water partition ratio and species weight". Environmental Toxicology and Chemistry. 20 (7): 1399–420. Bibcode:2001EnvTC..20.1399H. doi:10.1002/etc.5620200703. PMID 11434281. S2CID 25971836.
Cumming H, Rücker C (September 2017). "Octanol-Water Partition Coefficient Measurement by a Simple ¹H NMR Method". ACS Omega. 2 (9): 6244–6249. Bibcode:2017ACSOm...2.6244C. doi:10.1021/acsomega.7b01102. PMC 6644330. PMID 31457869.

archive.org (Global: 6^th place; English: 6^th place)

Martin YC (2010). "Chapter 4: The Hydrophobic Properties of Molecules". Quantitative Drug Design: A critical introduction (2nd ed.). Boca Raton: CRC Press/Taylor & Francis. pp. 66–73. ISBN 978-1-4200-7099-6.
Leo A, Hoekman DH, Hansch C (1995). "Octanol log P". Exploring QSAR, Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society. ISBN 978-0-8412-3060-6.

books.google.com (Global: 3^rd place; English: 3^rd place)

Kwon Y (2001). "4.2.4: Partition and Distribution Coefficients". Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for Industrial Scientists. New York: Kluwer Academic/Plenum Publishers. p. 44. ISBN 978-1-4757-8693-4.
Golan DE, Tashjian AH, Armstrong EJ, Armstrong AP (2008). "Chapter 15: General Anesthetic Pharmacology". Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy (2nd ed.). Philadelphia, Pa.: Lippincott Williams & Wilkins. p. 243. ISBN 978-0-7817-8355-2.
Machlin ES (2007). "Chapter 3: Free Energy and Phase Diagrams". An Introduction to Aspects of Thermodynamics and Kinetics Relevant to Materials Science (3rd ed.). Amsterdam: Elsevier. p. 98. ISBN 978-0-08-054968-2. Solid–solid equilibria equivalent to the solid–liquid case
McAuley W (2013). "Hydrophobicity and Partitioning". In Denton P, Rostron C (eds.). Pharmaceutics: The Science of Medicine Design. OUP Oxford. p. 129. ISBN 978-0-19-965531-1.
Bodor N, Buchwald P (2012). "Chapter 2.2: Pharmacokinetic Phase: ADME". Retrometabolic Drug Design and Targeting. (secondary). John Wiley & Sons, Inc. ISBN 978-1-118-40776-9.
van Leeuwin CJ, Hermens JL, eds. (2012). "Transport, Accumulation and Transformation Processes (Ch. 3), Properties of Chemicals and Estimation Methodologies (Ch. 7), and Procedures of Hazard and Risk Assessment (Ch. 8)". Risk Assessment of Chemicals: An Introduction. Dordrecht: Kluwer Acad. Publ. pp. 37–102, and 239–338, esp. 39ff, 240ff, 306, and passim. ISBN 978-0-7923-3740-9.

ddbst.com (Global: low place; English: low place)

"Octanol–Water Partition Coefficients". ddbst.com. Retrieved 19 March 2016.
"Dortmund Data Bank (DDB)". Dortmund Data Bank Software & Separation Technology (DDBST) GmbH. Retrieved 2020-05-20.

doi.org (Global: 2^nd place; English: 2^nd place)

Leo A, Hansch C, Elkins D (1971). "Partition coefficients and their uses". Chem. Rev. 71 (6): 525–616. doi:10.1021/cr60274a001.
Wilkinson AM, McNaught AD (1997). "Partition Coefficient". In Miloslav N, Jirát J, Košata B, Jenkins A, McNaught A (eds.). Compendium of Chemical Terminology: IUPAC Recommendations. Oxford: Blackwell Science. doi:10.1351/goldbook. ISBN 978-0-86542-684-9.
Comer J, Tam K (2001). "Lipophilicity Profiles: Theory and Measurement". In Testa B, van de Waterbed H, Folkers G, Guy R, Comer J, Tam K (eds.). Pharmacokinetic Optimization in Drug Research: Biological, Physicochemical, and Computational Strategies. Weinheim: Wiley-VCH. pp. 275–304. doi:10.1002/9783906390437.ch17. ISBN 978-3-906390-22-2.
Pagliara A, Carrupt PA, Caron G, Gaillard P, Testa B (1997). "Lipophilicity Profiles of Ampholytes". Chemical Reviews. 97 (8): 3385–3400. doi:10.1021/cr9601019. PMID 11851494.
Scherrer RA, Howard SM (January 1977). "Use of distribution coefficients in quantitative structure-activity relationships". Journal of Medicinal Chemistry. 20 (1): 53–8. doi:10.1021/jm00211a010. PMID 13215.
Manners CN, Payling DW, Smith DA (March 1988). "Distribution coefficient, a convenient term for the relation of predictable physico-chemical properties to metabolic processes". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 18 (3): 331–50. doi:10.3109/00498258809041669. PMID 3289270.
Wolfenden R (January 1978). "Interaction of the peptide bond with solvent water: a vapor phase analysis". (primary). Biochemistry. 17 (1): 201–4. doi:10.1021/bi00594a030. PMID 618544.
Collander R, Lindholm M, Haug CM, Stene J, Sörensen NA (1951). "The partition of organic compounds. between higher alcohols and water" (PDF). Acta Chem. Scand. 5: 774–780. doi:10.3891/acta.chem.scand.05-0774 (inactive 6 September 2025).{{cite journal}}: CS1 maint: DOI inactive as of September 2025 (link)
Whitehead KE, Geankoplis CJ (1955). "Separation of Formic and Sulfuric Acids by Extraction". Ind. Eng. Chem. 47 (10): 2114–2122. doi:10.1021/ie50550a029.
Brodsky J, Ballschmiter K (1988). "Reversed phase liquid chromatography of PCBs as a basis for calculation of water solubility and K_ow for polychlorobiphenyls". Fresenius' Z. Anal. Chem. 331 (3–4): 295–301. doi:10.1007/BF00481899. S2CID 91775126.
Sangster J (1989). "Octanol–Water Partition Coefficients of Simple Organic Compounds" (PDF). Journal of Physical and Chemical Reference Data. 18 (3): 1111–1227. Bibcode:1989JPCRD..18.1111S. doi:10.1063/1.555833. Archived from the original (PDF) on 2016-03-04. Retrieved 2017-07-13.
Mannhold R, Poda GI, Ostermann C, Tetko IV (March 2009). "Calculation of molecular lipophilicity: State-of-the-art and comparison of log P methods on more than 96,000 compounds". Journal of Pharmaceutical Sciences. 98 (3): 861–93. Bibcode:2009JPhmS..98..861M. doi:10.1002/jps.21494. PMID 18683876. S2CID 9595034.
Leeson PD, Springthorpe B (November 2007). "The influence of drug-like concepts on decision-making in medicinal chemistry". Nature Reviews. Drug Discovery. 6 (11): 881–90. Bibcode:2007NRvDD...6..881L. doi:10.1038/nrd2445. PMID 17971784. S2CID 205476574.
Edwards MP, Price DA (2010). Role of Physicochemical Properties and Ligand Lipophilicity Efficiency in Addressing Drug Safety Risks. Annual Reports in Medicinal Chemistry. Vol. 45. pp. 381–391. doi:10.1016/S0065-7743(10)45023-X. ISBN 978-0-12-380902-5.
Bodor N, Buchwald P (April 1999). "Recent advances in the brain targeting of neuropharmaceuticals by chemical delivery systems". Advanced Drug Delivery Reviews. 36 (2–3): 229–254. doi:10.1016/S0169-409X(98)00090-8. PMID 10837718.
Eisenberg D, McLachlan AD (1986). "Solvation energy in protein folding and binding". Nature. 319 (6050): 199–203. Bibcode:1986Natur.319..199E. doi:10.1038/319199a0. PMID 3945310. S2CID 21867582.
Miyamoto S, Kollman PA (September 1993). "What determines the strength of noncovalent association of ligands to proteins in aqueous solution?". Proceedings of the National Academy of Sciences of the United States of America. 90 (18): 8402–6. Bibcode:1993PNAS...90.8402M. doi:10.1073/pnas.90.18.8402. PMC 47364. PMID 8378312.
Cronin D, Mark T (2006). "The Role of Hydrophobicity in Toxicity Prediction". Current Computer-Aided Drug Design. 2 (4): 405–413. doi:10.2174/157340906778992346.
Heuel-Fabianek B (2006). "Partition Coefficients (K_d) for the Modelling of Transport Processes of Radionuclides in Groundwater" (PDF). Current Computer-Aided Drug Design. 2 (4): 405–413. doi:10.2174/157340906778992346.
Noble A (July 1993). "Partition coefficients (n-octanol—water) for pesticides". Journal of Chromatography A. 642 (1–2): 3–14. doi:10.1016/0021-9673(93)80072-G.
Dearden JC, Bresnan GM (1988). "The Measurement of Partition Coefficients". Quantitative Structure-Activity Relationships. 7 (3): 133–144. doi:10.1002/qsar.19880070304.
Andrés A, Rosés M, Ràfols C, Bosch E, Espinosa S, Segarra V, Huerta JM (August 2015). "Setup and validation of shake-flask procedures for the determination of partition coefficients (log D) from low drug amounts". European Journal of Pharmaceutical Sciences. 76: 181–91. doi:10.1016/j.ejps.2015.05.008. hdl:2445/143737. PMID 25968358.
Valkó K (May 2004). "Application of high-performance liquid chromatography based measurements of lipophilicity to model biological distribution". Journal of Chromatography A. 1037 (1–2): 299–310. Bibcode:2004JChA.1037..299V. doi:10.1016/j.chroma.2003.10.084. PMID 15214672.
Ulmeanu SM, Jensen H, Bouchard G, Carrupt PA, Girault HH (August 2003). "Water-oil partition profiling of ionized drug molecules using cyclic voltammetry and a 96-well microfilter plate system" (PDF). Pharmaceutical Research. 20 (8): 1317–22. doi:10.1023/A:1025025804196. PMID 12948031. S2CID 9917932.
Scholz F, Komorsky-Lovrić Š, Lovrić M (February 2000). "A new access to Gibbs energies of transfer of ions across liquid|liquid interfaces and a new method to study electrochemical processes at well-defined three-phase junctions". Electrochemistry Communications. 2 (2): 112–118. doi:10.1016/S1388-2481(99)00156-3.
Bond AM, Marken F (1994). "Mechanistic aspects of the electron and ion transport processes across the electrode". Journal of Electroanalytical Chemistry. 372 (1–2): 125–135. doi:10.1016/0022-0728(93)03257-P.
Karpińska, Aneta; Pilz, Marta; Buczkowska, Joanna; Żuk, Paweł J.; Kucharska, Karolina; Magiera, Gaweł; Kwapiszewska, Karina; Hołyst, Robert (2021). "Quantitative analysis of biochemical processes in living cells at a single-molecule level: a case of olaparib–PARP1 (DNA repair protein) interactions" (PDF). Analyst. 146 (23): 7131–7143. Bibcode:2021Ana...146.7131K. doi:10.1039/D1AN01769A. PMID 34726203. S2CID 240110114.
Karpinska, Aneta; Magiera, Gaweł; Kwapiszewska, Karina; Hołyst, Robert (2023). "Cellular Uptake of Bevacizumab in Cervical and Breast Cancer Cells Revealed by Single-Molecule Spectroscopy". J. Phys. Chem. Lett. 14 (5): 1272–1278. Bibcode:2023JPCL...14.1272K. doi:10.1021/acs.jpclett.2c03590. PMC 9923738. PMID 36719904. S2CID 256415374.
Nieto-Draghi C, Fayet G, Creton B, Rozanska X, Rotureau P, de Hemptinne JC, Ungerer P, Rousseau B, Adamo C (December 2015). "A General Guidebook for the Theoretical Prediction of Physicochemical Properties of Chemicals for Regulatory Purposes". Chemical Reviews. 115 (24): 13093–164. doi:10.1021/acs.chemrev.5b00215. PMID 26624238.
Judson R, Richard A, Dix DJ, Houck K, Martin M, Kavlock R, Dellarco V, Henry T, Holderman T, Sayre P, Tan S, Carpenter T, Smith E (May 2009). "The toxicity data landscape for environmental chemicals". Environmental Health Perspectives. 117 (5): 685–95. Bibcode:2009EnvHP.117..685J. doi:10.1289/ehp.0800168. PMC 2685828. PMID 19479008.
Matter H, Baringhaus KH, Naumann T, Klabunde T, Pirard B (September 2001). "Computational approaches towards the rational design of drug-like compound libraries". Combinatorial Chemistry & High Throughput Screening. 4 (6): 453–75. doi:10.2174/1386207013330896. PMID 11562252.
Schuffenhauer A, Ruedisser S, Marzinzik AL, Jahnke W, Blommers M, Selzer P, Jacoby E (2005). "Library design for fragment based screening". Current Topics in Medicinal Chemistry. 5 (8): 751–62. doi:10.2174/1568026054637700. PMID 16101415.
Ghose AK, Crippen GM (1986). "Atomic Physicochemical Parameters for Three-Dimensional Structure-Directed Quantitative Structure–Activity Relationships I. Partition Coefficients as a Measure of Hydrophobicity" (PDF). Journal of Computational Chemistry. 7 (4): 565–577. doi:10.1002/jcc.540070419. hdl:2027.42/38274. S2CID 4272062.
Cheng T, Zhao Y, Li X, Lin F, Xu Y, Zhang X, Li Y, Wang R, Lai L (2007). "Computation of octanol-water partition coefficients by guiding an additive model with knowledge". Journal of Chemical Information and Modeling. 47 (6): 2140–8. doi:10.1021/ci700257y. PMID 17985865.
Moriguchi I, Hirono S, Liu Q, Nakagome I, Matsushita Y (1992). "Simple method of calculating octanol/water partition coefficient". Chem. Pharm. Bull. 40 (1): 127–130. doi:10.1248/cpb.40.127.
Ghose AK, Viswanadhan VN, Wendoloski JJ (1998). "Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragmental Methods: An Analysis of AlogP and ClogP Methods". Journal of Physical Chemistry A. 102 (21): 3762–3772. Bibcode:1998JPCA..102.3762G. doi:10.1021/jp980230o.
Liao Q, Yao J, Yuan S (August 2006). "SVM approach for predicting LogP". Molecular Diversity. 10 (3): 301–9. doi:10.1007/s11030-006-9036-2. PMID 17031534. S2CID 1196330.
Molnár L, Keseru GM, Papp A, Gulyás Z, Darvas F (February 2004). "A neural network based prediction of octanol-water partition coefficients using atomic5 fragmental descriptors". Bioorganic & Medicinal Chemistry Letters. 14 (4): 851–3. doi:10.1016/j.bmcl.2003.12.024. PMID 15012980.
Perrin DD, Dempsey B, Serjeant EP (1981). "Chapter 3: Methods of pK_a Prediction". pK_a Prediction for Organic Acids and Bases. London: Chapman & Hall. pp. 21–26. doi:10.1007/978-94-009-5883-8. ISBN 978-0-412-22190-3.
Fraczkiewicz R (2013). "In Silico Prediction of Ionization". In Reedijk J (ed.). Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering [Online]. Vol. 5. Amsterdam, the Netherlands: Elsevier. doi:10.1016/B978-0-12-409547-2.02610-X. ISBN 9780124095472.
Pinsuwan S, Li A, Yalkowsky SH (May 1995). "Correlation of Octanol/Water Solubility Ratios and Partition Coefficients". Journal of Chemical & Engineering Data. 40 (3): 623–626. Bibcode:1995JCED...40..623P. doi:10.1021/je00019a019.
Wang J, Hou T (June 2011). "Recent advances on aqueous solubility prediction". Combinatorial Chemistry & High Throughput Screening. 14 (5): 328–38. doi:10.2174/138620711795508331. PMID 21470182.
Skyner RE, McDonagh JL, Groom CR, van Mourik T, Mitchell JB (March 2015). "A review of methods for the calculation of solution free energies and the modelling of systems in solution" (PDF). Physical Chemistry Chemical Physics. 17 (9): 6174–91. Bibcode:2015PCCP...17.6174S. doi:10.1039/c5cp00288e. PMID 25660403.
Hodges G, Eadsforth C, Bossuyt B, Bouvy A, Enrici MH, Geurts M, et al. (2019). "A comparison of log Kow (n-octanol–water partition coefficient) values for non-ionic, anionic, cationic and amphoteric surfactants determined using predictions and experimental methods". Environmental Sciences Europe. 31 (1) 1. Bibcode:2019ESEur..31....1H. doi:10.1186/s12302-018-0176-7.
Hendriks AJ, van der Linde A, Cornelissen G, Sijm DT (July 2001). "The power of size. 1. Rate constants and equilibrium ratios for accumulation of organic substances related to octanol-water partition ratio and species weight". Environmental Toxicology and Chemistry. 20 (7): 1399–420. Bibcode:2001EnvTC..20.1399H. doi:10.1002/etc.5620200703. PMID 11434281. S2CID 25971836.
Cumming H, Rücker C (September 2017). "Octanol-Water Partition Coefficient Measurement by a Simple ¹H NMR Method". ACS Omega. 2 (9): 6244–6249. Bibcode:2017ACSOm...2.6244C. doi:10.1021/acsomega.7b01102. PMC 6644330. PMID 31457869.

elsevier.com (Global: 365^th place; English: 372^nd place)

linkinghub.elsevier.com

Scholz F, Komorsky-Lovrić Š, Lovrić M (February 2000). "A new access to Gibbs energies of transfer of ions across liquid|liquid interfaces and a new method to study electrochemical processes at well-defined three-phase junctions". Electrochemistry Communications. 2 (2): 112–118. doi:10.1016/S1388-2481(99)00156-3.

epa.gov (Global: 961^st place; English: 595^th place)

nepis.epa.gov

Wasik SP, Tewari YB, Miller MM, Martire DE (1981). "Octanol–Water Partition Coefficients and Aqueous Solubilities of Organic Compounds". NBS Techn. Rep. 81 (2406): S1–56.

epfl.ch (Global: 3,783^rd place; English: 3,769^th place)

infoscience.epfl.ch

Ulmeanu SM, Jensen H, Bouchard G, Carrupt PA, Girault HH (August 2003). "Water-oil partition profiling of ionized drug molecules using cyclic voltammetry and a 96-well microfilter plate system" (PDF). Pharmaceutical Research. 20 (8): 1317–22. doi:10.1023/A:1025025804196. PMID 12948031. S2CID 9917932.

fz-juelich.de (Global: low place; English: low place)

juser.fz-juelich.de

Heuel-Fabianek B (2006). "Partition Coefficients (K_d) for the Modelling of Transport Processes of Radionuclides in Groundwater" (PDF). Current Computer-Aided Drug Design. 2 (4): 405–413. doi:10.2174/157340906778992346.

hdl.handle.net (Global: 66^th place; English: 34^th place)

Andrés A, Rosés M, Ràfols C, Bosch E, Espinosa S, Segarra V, Huerta JM (August 2015). "Setup and validation of shake-flask procedures for the determination of partition coefficients (log D) from low drug amounts". European Journal of Pharmaceutical Sciences. 76: 181–91. doi:10.1016/j.ejps.2015.05.008. hdl:2445/143737. PMID 25968358.
Ghose AK, Crippen GM (1986). "Atomic Physicochemical Parameters for Three-Dimensional Structure-Directed Quantitative Structure–Activity Relationships I. Partition Coefficients as a Measure of Hydrophobicity" (PDF). Journal of Computational Chemistry. 7 (4): 565–577. doi:10.1002/jcc.540070419. hdl:2027.42/38274. S2CID 4272062.

iupac.org (Global: 1,291^st place; English: 1,832^nd place)

goldbook.iupac.org

Wilkinson AM, McNaught AD (1997). "Partition Coefficient". In Miloslav N, Jirát J, Košata B, Jenkins A, McNaught A (eds.). Compendium of Chemical Terminology: IUPAC Recommendations. Oxford: Blackwell Science. doi:10.1351/goldbook. ISBN 978-0-86542-684-9.

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eprints.lancs.ac.uk

Karpińska, Aneta; Pilz, Marta; Buczkowska, Joanna; Żuk, Paweł J.; Kucharska, Karolina; Magiera, Gaweł; Kwapiszewska, Karina; Hołyst, Robert (2021). "Quantitative analysis of biochemical processes in living cells at a single-molecule level: a case of olaparib–PARP1 (DNA repair protein) interactions" (PDF). Analyst. 146 (23): 7131–7143. Bibcode:2021Ana...146.7131K. doi:10.1039/D1AN01769A. PMID 34726203. S2CID 240110114.

nih.gov (Global: 5^th place; English: 5^th place)

pubmed.ncbi.nlm.nih.gov

Pagliara A, Carrupt PA, Caron G, Gaillard P, Testa B (1997). "Lipophilicity Profiles of Ampholytes". Chemical Reviews. 97 (8): 3385–3400. doi:10.1021/cr9601019. PMID 11851494.
Scherrer RA, Howard SM (January 1977). "Use of distribution coefficients in quantitative structure-activity relationships". Journal of Medicinal Chemistry. 20 (1): 53–8. doi:10.1021/jm00211a010. PMID 13215.
Manners CN, Payling DW, Smith DA (March 1988). "Distribution coefficient, a convenient term for the relation of predictable physico-chemical properties to metabolic processes". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 18 (3): 331–50. doi:10.3109/00498258809041669. PMID 3289270.
Wolfenden R (January 1978). "Interaction of the peptide bond with solvent water: a vapor phase analysis". (primary). Biochemistry. 17 (1): 201–4. doi:10.1021/bi00594a030. PMID 618544.
Mannhold R, Poda GI, Ostermann C, Tetko IV (March 2009). "Calculation of molecular lipophilicity: State-of-the-art and comparison of log P methods on more than 96,000 compounds". Journal of Pharmaceutical Sciences. 98 (3): 861–93. Bibcode:2009JPhmS..98..861M. doi:10.1002/jps.21494. PMID 18683876. S2CID 9595034.
Leeson PD, Springthorpe B (November 2007). "The influence of drug-like concepts on decision-making in medicinal chemistry". Nature Reviews. Drug Discovery. 6 (11): 881–90. Bibcode:2007NRvDD...6..881L. doi:10.1038/nrd2445. PMID 17971784. S2CID 205476574.
Bodor N, Buchwald P (April 1999). "Recent advances in the brain targeting of neuropharmaceuticals by chemical delivery systems". Advanced Drug Delivery Reviews. 36 (2–3): 229–254. doi:10.1016/S0169-409X(98)00090-8. PMID 10837718.
Kubinyi H (March 1979). "Nonlinear dependence of biological activity on hydrophobic character: the bilinear model". Il Farmaco; Edizione Scientifica. 34 (3): 248–76. PMID 43264.
Kubinyi H (1979). "Lipophilicity and biological activity. Drug transport and drug distribution in model systems and in biological systems". Arzneimittel-Forschung. 29 (8): 1067–80. PMID 40579.
Eisenberg D, McLachlan AD (1986). "Solvation energy in protein folding and binding". Nature. 319 (6050): 199–203. Bibcode:1986Natur.319..199E. doi:10.1038/319199a0. PMID 3945310. S2CID 21867582.
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Karpińska, Aneta; Pilz, Marta; Buczkowska, Joanna; Żuk, Paweł J.; Kucharska, Karolina; Magiera, Gaweł; Kwapiszewska, Karina; Hołyst, Robert (2021). "Quantitative analysis of biochemical processes in living cells at a single-molecule level: a case of olaparib–PARP1 (DNA repair protein) interactions" (PDF). Analyst. 146 (23): 7131–7143. Bibcode:2021Ana...146.7131K. doi:10.1039/D1AN01769A. PMID 34726203. S2CID 240110114.
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Cheng T, Zhao Y, Li X, Lin F, Xu Y, Zhang X, Li Y, Wang R, Lai L (2007). "Computation of octanol-water partition coefficients by guiding an additive model with knowledge". Journal of Chemical Information and Modeling. 47 (6): 2140–8. doi:10.1021/ci700257y. PMID 17985865.
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Hendriks AJ, van der Linde A, Cornelissen G, Sijm DT (July 2001). "The power of size. 1. Rate constants and equilibrium ratios for accumulation of organic substances related to octanol-water partition ratio and species weight". Environmental Toxicology and Chemistry. 20 (7): 1399–420. Bibcode:2001EnvTC..20.1399H. doi:10.1002/etc.5620200703. PMID 11434281. S2CID 25971836.
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ncbi.nlm.nih.gov

Miyamoto S, Kollman PA (September 1993). "What determines the strength of noncovalent association of ligands to proteins in aqueous solution?". Proceedings of the National Academy of Sciences of the United States of America. 90 (18): 8402–6. Bibcode:1993PNAS...90.8402M. doi:10.1073/pnas.90.18.8402. PMC 47364. PMID 8378312.
Karpinska, Aneta; Magiera, Gaweł; Kwapiszewska, Karina; Hołyst, Robert (2023). "Cellular Uptake of Bevacizumab in Cervical and Breast Cancer Cells Revealed by Single-Molecule Spectroscopy". J. Phys. Chem. Lett. 14 (5): 1272–1278. Bibcode:2023JPCL...14.1272K. doi:10.1021/acs.jpclett.2c03590. PMC 9923738. PMID 36719904. S2CID 256415374.
Judson R, Richard A, Dix DJ, Houck K, Martin M, Kavlock R, Dellarco V, Henry T, Holderman T, Sayre P, Tan S, Carpenter T, Smith E (May 2009). "The toxicity data landscape for environmental chemicals". Environmental Health Perspectives. 117 (5): 685–95. Bibcode:2009EnvHP.117..685J. doi:10.1289/ehp.0800168. PMC 2685828. PMID 19479008.
Cumming H, Rücker C (September 2017). "Octanol-Water Partition Coefficient Measurement by a Simple ¹H NMR Method". ACS Omega. 2 (9): 6244–6249. Bibcode:2017ACSOm...2.6244C. doi:10.1021/acsomega.7b01102. PMC 6644330. PMID 31457869.

nist.gov (Global: 708^th place; English: 742^nd place)

Sangster J (1989). "Octanol–Water Partition Coefficients of Simple Organic Compounds" (PDF). Journal of Physical and Chemical Reference Data. 18 (3): 1111–1227. Bibcode:1989JPCRD..18.1111S. doi:10.1063/1.555833. Archived from the original (PDF) on 2016-03-04. Retrieved 2017-07-13.

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Rutkowska E, Pajak K, Jóźwiak K (2013). "Lipophilicity--methods of determination and its role in medicinal chemistry" (PDF). Acta Poloniae Pharmaceutica. 70 (1): 3–18. PMID 23610954.

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Eisenberg D, McLachlan AD (1986). "Solvation energy in protein folding and binding". Nature. 319 (6050): 199–203. Bibcode:1986Natur.319..199E. doi:10.1038/319199a0. PMID 3945310. S2CID 21867582.
Ulmeanu SM, Jensen H, Bouchard G, Carrupt PA, Girault HH (August 2003). "Water-oil partition profiling of ionized drug molecules using cyclic voltammetry and a 96-well microfilter plate system" (PDF). Pharmaceutical Research. 20 (8): 1317–22. doi:10.1023/A:1025025804196. PMID 12948031. S2CID 9917932.
Karpińska, Aneta; Pilz, Marta; Buczkowska, Joanna; Żuk, Paweł J.; Kucharska, Karolina; Magiera, Gaweł; Kwapiszewska, Karina; Hołyst, Robert (2021). "Quantitative analysis of biochemical processes in living cells at a single-molecule level: a case of olaparib–PARP1 (DNA repair protein) interactions" (PDF). Analyst. 146 (23): 7131–7143. Bibcode:2021Ana...146.7131K. doi:10.1039/D1AN01769A. PMID 34726203. S2CID 240110114.
Karpinska, Aneta; Magiera, Gaweł; Kwapiszewska, Karina; Hołyst, Robert (2023). "Cellular Uptake of Bevacizumab in Cervical and Breast Cancer Cells Revealed by Single-Molecule Spectroscopy". J. Phys. Chem. Lett. 14 (5): 1272–1278. Bibcode:2023JPCL...14.1272K. doi:10.1021/acs.jpclett.2c03590. PMC 9923738. PMID 36719904. S2CID 256415374.
Ghose AK, Crippen GM (1986). "Atomic Physicochemical Parameters for Three-Dimensional Structure-Directed Quantitative Structure–Activity Relationships I. Partition Coefficients as a Measure of Hydrophobicity" (PDF). Journal of Computational Chemistry. 7 (4): 565–577. doi:10.1002/jcc.540070419. hdl:2027.42/38274. S2CID 4272062.
Liao Q, Yao J, Yuan S (August 2006). "SVM approach for predicting LogP". Molecular Diversity. 10 (3): 301–9. doi:10.1007/s11030-006-9036-2. PMID 17031534. S2CID 1196330.
Hendriks AJ, van der Linde A, Cornelissen G, Sijm DT (July 2001). "The power of size. 1. Rate constants and equilibrium ratios for accumulation of organic substances related to octanol-water partition ratio and species weight". Environmental Toxicology and Chemistry. 20 (7): 1399–420. Bibcode:2001EnvTC..20.1399H. doi:10.1002/etc.5620200703. PMID 11434281. S2CID 25971836.

sioc-ccbg.ac.cn (Global: low place; English: low place)

Cheng T, Zhao Y, Li X, Lin F, Xu Y, Zhang X, Li Y, Wang R, Lai L (2007). "Computation of octanol-water partition coefficients by guiding an additive model with knowledge". Journal of Chemical Information and Modeling. 47 (6): 2140–8. doi:10.1021/ci700257y. PMID 17985865.

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Skyner RE, McDonagh JL, Groom CR, van Mourik T, Mitchell JB (March 2015). "A review of methods for the calculation of solution free energies and the modelling of systems in solution" (PDF). Physical Chemistry Chemical Physics. 17 (9): 6174–91. Bibcode:2015PCCP...17.6174S. doi:10.1039/c5cp00288e. PMID 25660403.

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Ghose AK, Crippen GM (1986). "Atomic Physicochemical Parameters for Three-Dimensional Structure-Directed Quantitative Structure–Activity Relationships I. Partition Coefficients as a Measure of Hydrophobicity" (PDF). Journal of Computational Chemistry. 7 (4): 565–577. doi:10.1002/jcc.540070419. hdl:2027.42/38274. S2CID 4272062.

web.archive.org (Global: 1^st place; English: 1^st place)

Sangster J (1989). "Octanol–Water Partition Coefficients of Simple Organic Compounds" (PDF). Journal of Physical and Chemical Reference Data. 18 (3): 1111–1227. Bibcode:1989JPCRD..18.1111S. doi:10.1063/1.555833. Archived from the original (PDF) on 2016-03-04. Retrieved 2017-07-13.

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Sangster J (1997). Octanol-water partition coefficients : fundamentals and physical chemistry. Chichester: Wiley. ISBN 0-471-97397-1. OCLC 36430034.
Mackay, D; Parnis, J. Mark (2021). Multimedia Environmental Models: The Fugacity Approach (Third ed.). Boca Raton, FL: CRC Press. ISBN 978-1-000-09499-2. OCLC 1182869019.

Partition coefficient (English Wikipedia)

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