Analysis of information sources in references of the Wikipedia article "维生素C" in Chinese language version.
Antioxidant vitamin supplementation has no effect on the incidence of major cardiovascular events, myocardial infarction, stroke, total death, and cardiac death.
The HIFalpha hydroxylases belong to a superfamily of dioxygenases that require the co-substrates oxygen and 2-oxoglutarate as well as the cofactors Fe2+ and ascorbate. The regulation of enzyme turnover by the concentration of the cosubstrate oxygen constitutes the interface between tissue oxygen level and the activity of HIF. The HIFalpha prolyl hydroxylases, termed PHDs/EGLNs (prolyl hydroxylase domain proteins/EGL nine homologues), bind to a conserved Leu-Xaa-Xaa-Leu-Ala-Pro motif present in all substrates identified so far.
"Plasma vitamin C concentrations are maintained between 10 and 160 μM, and any excess of the vitamin is excreted by the kidney. In contrast, the vitamin is concentrated to at least 100 times the plasma level in specific tissues such as the adrenal glands, pituitary gland, thymus, retina, corpus luteum, and a variety of neuronal cell types."
Antioxidant vitamin supplementation has no effect on the incidence of major cardiovascular events, myocardial infarction, stroke, total death, and cardiac death.
The HIFalpha hydroxylases belong to a superfamily of dioxygenases that require the co-substrates oxygen and 2-oxoglutarate as well as the cofactors Fe2+ and ascorbate. The regulation of enzyme turnover by the concentration of the cosubstrate oxygen constitutes the interface between tissue oxygen level and the activity of HIF. The HIFalpha prolyl hydroxylases, termed PHDs/EGLNs (prolyl hydroxylase domain proteins/EGL nine homologues), bind to a conserved Leu-Xaa-Xaa-Leu-Ala-Pro motif present in all substrates identified so far.
Federal approval of a clinical trial on intravenous vitamin C as a cancer treatment lends credence to alternative cancer care, U.S. researchers said.
In recognition of this medical breakthrough, some scientists believe that King deserved a Nobel Prize.
"Plasma vitamin C concentrations are maintained between 10 and 160 μM, and any excess of the vitamin is excreted by the kidney. In contrast, the vitamin is concentrated to at least 100 times the plasma level in specific tissues such as the adrenal glands, pituitary gland, thymus, retina, corpus luteum, and a variety of neuronal cell types."
In recognition of this medical breakthrough, some scientists believe that King deserved a Nobel Prize.
Federal approval of a clinical trial on intravenous vitamin C as a cancer treatment lends credence to alternative cancer care, U.S. researchers said.